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CORDIS - Forschungsergebnisse der EU
CORDIS

Ensuring long-term sustainability of excellence in chemical biology within Europe and beyond

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Recommendations for data reproducibility training (öffnet in neuem Fenster)

D64 Recommendations for data reproducibility training M36 EUOS

Improved protocols for compound sourcing and acquisition based on EU-OS Ambassador feedback, including a directory of cooperating chemists from each country (öffnet in neuem Fenster)

D2.1 Improved protocols for compound sourcing and acquisition based on EU-OS Ambassador feedback, including a directory of cooperating chemists from each country (M12) (UH, USC)

Report on implementation of enhanced transfer procedures for data from EU-OS partner sites (öffnet in neuem Fenster)

D62 Report on implementation of enhanced transfer procedures for data from EUOS partner sites M55 EUOS

Publication describing the performance of the fragment library in screening campaigns (öffnet in neuem Fenster)

D42 Publication describing the performance of the fragment library in screening campaigns M40 OSI EMBL

Report on scientific publications and dissemination / outreach activities to new communities (öffnet in neuem Fenster)

D93 Report on scientific publications and dissemination outreach activities to new communities M56 EUOS

Gender action plan (öffnet in neuem Fenster)

D9.2 Gender action plan (M12) (EU-OS)

Report on outcomes of the chemical optimisation projects (öffnet in neuem Fenster)

D32 Report on outcomes of the chemical optimisation projects including of gaps in medicinal chemistry services and recommendation for process improvements for EUOS operation M55 EUOS

Mode of action or compound distribution report for compounds from selected projects from phase 1 (responsibility of sites providing access) (öffnet in neuem Fenster)

D51 Mode of action or compound distribution report for compounds from selected projects from phase 1 responsibility of sites providing access M33 IME

Mode of action or compound distribution report for compounds from selected projects from phase 2 (responsibility of sites providing access) (öffnet in neuem Fenster)

D52 Mode of action or compound distribution report for compounds from selected projects from phase 2 responsibility of sites providing access M48 IME

Report on the status of co-developed screening technologies (öffnet in neuem Fenster)

D72 Report on the status of codeveloped screening technologies M56 USC UiO

Report on available courses relevant for users and staff of EU-OS (öffnet in neuem Fenster)

D8.1 Report on available courses relevant for users and staff of EU-OS (M12) (IMG)

Report on outcomes of the screening projects (öffnet in neuem Fenster)

D31 Report on outcomes of the screening projects including identification of gaps in screening services and recommendation for process improvements for EUOS operation M35 EUOS

Report on improvements to the access and workflows. (öffnet in neuem Fenster)

D1.1 Report on improvements to the access and workflows (M12) (EU-OS)

Innovation management plan (öffnet in neuem Fenster)

D73 Innovation management plan M56 USC UiO

Report on the translation module for EU-OS screening centres (öffnet in neuem Fenster)

D63 Report on the translation module for EUOS screening centres M55 EUOS

FBDD chemical evolution consultation service guidelines (öffnet in neuem Fenster)

D4.1 FBDD chemical evolution consultation service guidelines (M12) (OSI, HZI)

Management guidelines (öffnet in neuem Fenster)

D9.1 Management guidelines (M2) (EU-OS)

Report on engagement measures and successes for extension of EU-OS membership (öffnet in neuem Fenster)

D13 Report on engagement measures and successes for extension of EUOS membership M55 EUOS

Enhanced Business Plan and financial sustainability model based on EU-OS-DRIVE outcomes (öffnet in neuem Fenster)

D15 Enhanced Business Plan and financial sustainability model based on EUOSDRIVE outcomes M56 EUOS

Data Management Plan (öffnet in neuem Fenster)

D6.5 Data Management Plan (M6) (EU-OS)

Final report on the EU-OS academic compound library (öffnet in neuem Fenster)

D23 Final report on the EUOS academic compound library to include metrics on compound acquisition quality diversity uniqueness etc summaries of training events organized and recommendations for future acquisition campaigns M56 UH USC

Report on report on sustainability aspects and future perspectives for forming major strategic cooperations in the fields of chemical biology and academic drug discovery. Audiences are policy makers and funding bodies (öffnet in neuem Fenster)

D94 Report on report on sustainability aspects and future perspectives for forming major strategic cooperations in the fields of chemical biology and academic drug discovery Audiences are policy makers and funding bodies M57 EUOS

Report on co-ordination of joined training with other BMS ESFRI projects and establishing new collaborative links (öffnet in neuem Fenster)

D8.3 Report on co-ordination of joined training with other BMS ESFRI projects and establishing new collaborative links (M18) (IMG)

Report on existing data transfer procedures and gap analysis (öffnet in neuem Fenster)

D6.1 Report on existing data transfer procedures and gap analysis (M6) (EU-OS)

Report on the evaluation of tools to improve compound registration (öffnet in neuem Fenster)

D2.2 Report on the evaluation of tools to improve compound registration (M18) (UH, USC)

Roadmap for industry interactions and establishment of industry involvement in EU-OS’s activities (öffnet in neuem Fenster)

D7.1 Roadmap for industry interactions and establishment of industry involvement in EU-OS’s activities (M8) (USC, UiO)

Report on newly developed courses organized by EU-OS-DRIVE (öffnet in neuem Fenster)

D8.2 Report on newly developed courses organized by EU-OS-DRIVE (M18) (IMG)

Handbook and defined user workflows for two new categories of partner sites (öffnet in neuem Fenster)

D12 Handbook and defined user workflows for two new categories of partner sites M46 EUOS

Delivery of periodic, mid-term and final reports (öffnet in neuem Fenster)

D9.5 Delivery of periodic, mid-term and final reports (M12, 24, 36, 48) (EU-OS) due M12, M24, M36, M48

Socio-economic impact study and documented refined KPIs (öffnet in neuem Fenster)

D1.4 Socio-economic impact study and documented refined KPIs (M56) (EU-OS)

Open Research Data Pilot (öffnet in neuem Fenster)

Note The Assay Providing User may request an optional grace period which allows for an indepth characterisation of the identified compounds and facilitates the publication of research findings in highlevel peerreviewed journals or the application for a patent If an IP position is being sought then a grace period of up to 24 month with the possibility to extend to 36 months in exceptional circumstances may be granted These grace periods align with current practice of other initiatives eg the IMI European Lead Factory which plans to release the Qualifiedhitlists of their projects after a defined grace period

Veröffentlichungen

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking (öffnet in neuem Fenster)

Autoren: Schuller, Marion Correy, Galen J. Gahbauer, Stefan Fearon, Daren Wu, Taiasean Díaz, Roberto Efraín Young, Iris D. Martins, Luan Carvalho Smith, Dominique H. Schulze-Gahmen, Ursula Owens, Tristan W. Deshpande, Ishan Merz, Gregory E. Thwin, Aye C. Biel, Justin T. Peters, Jessica K. Moritz, Michelle Herrera, Nadia Kratochvil, Huong T. Aimon, Anthony Bennett, James M. Neto, Jose Brandao Cohen, Aina
Veröffentlicht in: Science Advances, Ausgabe Vol 7, Ausgabe 16, 2021, Seite(n) eabf8711, ISSN 2375-2548
Herausgeber: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abf8711

HTSDSF Explorer, A Novel Tool to Analyze High-throughput DSF Screenings (öffnet in neuem Fenster)

Autoren: Pau Martin-Malpartida, Emil Hausvik, Jarl Underhaug, CarlesTorner, AuroraMartinez, Maria J.Macias
Veröffentlicht in: JMB Journal of Molecular Biology, Ausgabe Volume 434, Ausgabe 11, 15 June 2022, 167372, 2022, ISSN 0022-2836
Herausgeber: Academic Press
DOI: 10.1016/j.jmb.2021.167372

Modulation of Mitochondria–Endoplasmic Reticulum Contacts (MERCs) by Small Molecules as a New Strategy for Restoring Lipid Metabolism in an Amyotrophic Lateral Sclerosis Model (öffnet in neuem Fenster)

Autoren: Mikel Etxebeste-Mitxeltorena, Hector Flores-Romero, Sandra Ramos-Inza, Esther Masiá, Maria Nenchova, Jorge Montesinos, Loreto Martinez-Gonzalez, Gracia Porras, Mar Orzáez, María J. Vicent, Carmen Gil, Estela Area-Gomez, Ana J. Garcia-Saez, Ana Martinez
Veröffentlicht in: Journal of Medicinal Chemistry, 2025, ISSN 0022-2623
Herausgeber: American Chemical Society
DOI: 10.1021/acs.jmedchem.4c01368

Academic collaborative models fostering the translation of physiological in vitro systems from basic research into drug discovery (öffnet in neuem Fenster)

Autoren: Alessandra Silvestri, Francisca Vicente, María J.Vicent, Bahne Stechmann, Wolfgang Fecke
Veröffentlicht in: Drug Discovery Today, Ausgabe Volume 26, Ausgabe 6, June 2021, 2021, Seite(n) Pages 1369-1381, ISSN 1359-6446
Herausgeber: Elsevier BV
DOI: 10.1016/j.drudis.2021.02.024

MBC and ECBL libraries: outstanding tools for drug discovery (öffnet in neuem Fenster)

Autoren: Tiziana Ginex; Enrique Madruga; Ana Martinez; Carmen Gil
Veröffentlicht in: Frontiers in Pharmacology, Ausgabe Volume 14 - 2023, 2023, ISSN 1663-9812
Herausgeber: Frontiers Media S.A.
DOI: 10.3389/fphar.2023.1244317

A Rapid, Convergent Approach to the Identification of Exosome Inhibitors in Breast Cancer Models (öffnet in neuem Fenster)

Autoren: Zoraida Andreu; Esther Masiá; David Charbonnier; María J. Vicent
Veröffentlicht in: Nanotheranostics, Ausgabe 2023 Jan 1;7(1):1-21., 2023, ISSN 2206-7418
Herausgeber: Ivyspring International Publisher
DOI: 10.7150/ntno.73606

Development and Characterization of a FKBP51FK1 Affinity Matrix for Protein-Protein Interaction Studies

Autoren: Stephanie Merz
Veröffentlicht in: 2022
Herausgeber: TU Darmstadt, Germany

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