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A Novel Detection protocols for REliable prostate cancer Assays

Objective

The technology validation was successfully completed indicating a great commercial potential, and the innovative and inventive aspects of the assay platform are now covered by the filed priority European Patent Office (EPO) patent applications. Validated glycoprofiling of the proteins now uses lectins in a format, fully compatible with clinical PSA assay kits. This PoC grant focuses on 1. Pre-clinical retrospective validation of the early stage biomarker of prostate cancer (PCa) and 2. Commercialisation of the PCa diagnostics kit. Pre-clinical (60 human serum samples) is ongoing and retrospective validation study (450 human serum samples) of the assay will be performed by statistical analysis using a receiver operating characteristic (ROC) curve. The PoC describes all steps, which have been developed so far and all necessary steps, which need to be done for retrospective validation study, product development and commercialisation through our newly incorporated start-up Glycanostics Ltd. (www.glycanostics.com). We will provide PCa diagnostic test resulting in a second opinion to guide the right decision if the biopsy is needed. This will avoid the needless and unreliable biopsies and in the future rival an inaccurate PSA testing.

Host institution

CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED
Net EU contribution
€ 87 500,00
Address
Dubravska Cesta 9
845 Bratislava
Slovakia

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Region
Slovensko Bratislavský kraj Bratislavský kraj
Activity type
Research Organisations
Other funding
€ 87 500,00

Beneficiaries (2)

CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED
Slovakia
Net EU contribution
€ 87 500,00
Address
Dubravska Cesta 9
845 Bratislava

See on map

Region
Slovensko Bratislavský kraj Bratislavský kraj
Activity type
Research Organisations
Other funding
€ 87 500,00
GLYCANOSTICS SRO
Slovakia
Net EU contribution
€ 61 999,93
Address
Kudlakova 1848/7
841 01 Bratislava

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Slovensko Bratislavský kraj Bratislavský kraj
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 61 999,93