CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease

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Pubblicazioni

Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis

Autori: Isidore Mushimiyimana, Henri Niskanen, Mustafa Beter, Johanna P Laakkonen, Minna U Kaikkonen, Seppo Ylä-Herttuala, Nihay Laham-Karam
Pubblicato in: Nucleic Acids Research, Numero 49, 2021, Pagina/e 8078-8096, ISSN 0305-1048
Editore: Oxford University Press
DOI: 10.1093/nar/gkab633

Antagonism of miRNA in heart failure: first evidence in human

Autori: Andrew H. Baker and Mauro Giacca
Pubblicato in: European Heart Journal, 2021, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehaa967

AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes

Autori: Laura Rode; Christian Bär; Sonja Groß; Axel Rossi; Nadja Meumann; Janika Viereck; Naisam Abbas; Ke Xiao; Isabelle Riedel; Anika Gietz; Karina Zimmer; Margarete Odenthal; Hildegard Büning; Thomas Thum
Pubblicato in: Crossref, Numero 4, 2023, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.ymthe.2022.07.003

Neuro-oncological Ventral Antigen 2 Regulates Splicing of Vascular Endothelial Growth Factor Receptor 1 and Is Required for Endothelial Function

Autori: Veerle Kremer, Jetta J. Oppelaar, Theresa Gimbel, Susanne Koziarek, Wessel Ganzevoort, Mariëlle G. van Pampus, Bert-Jan van den Born, Liffert Vogt, Christianne de Groot, Reinier A. Boon
Pubblicato in: Reproductive Sciences, Numero 30, 2023, Pagina/e 678-689, ISSN 1933-7191
Editore: SAGE Publications
DOI: 10.1007/s43032-022-01044-4

MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease

Autori: João P. Monteiro, Julie Rodor, Axelle Caudrillier, Jessica P. Scanlon, Ana-Mishel Spiroski, Tatiana Dudnakova, Beatrice Pflüger-Müller, Alena Shmakova, Alex von Kriegsheim, Lin Deng, Richard S. Taylor, John R. Wilson-Kanamori, Shiau-Haln Chen, Kevin Stewart, Adrian Thomson, Tijana Mitić, John D. McClure, Jean Iynikkel, Patrick W.F. Hadoke, Laura Denby, Angela C. Bradshaw, Paola Caruso, Nichola
Pubblicato in: Circulation Research, Numero 128, 2024, Pagina/e 1173-1190, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.318124

Gene editing for cardiomyopathy takes a step forward

Autori: Mauro Giacca
Pubblicato in: Cardiovascular Research, Numero 118, 2023, Pagina/e 3011-3012, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvac164

Fulfilling the Promise of RNA Therapies for Cardiac Repair and Regeneration

Autori: Mauro Giacca
Pubblicato in: Stem Cells Translational Medicine, Numero 12, 2023, Pagina/e 527-535, ISSN 2157-6564
Editore: AlphaMed Press
DOI: 10.1093/stcltm/szad038

<i>CARMN</i> Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice

Autori: Francesca Vacante, Julie Rodor, Mukesh K. Lalwani, Amira D. Mahmoud, Matthew Bennett, Azzurra L. De Pace, Eileen Miller, Kim Van Kuijk, Jenny de Bruijn, Marion Gijbels, Thomas C. Williams, Michael B. Clark, Jessica P. Scanlon, Amanda C. Doran, Rusty Montgomery, David E. Newby, Mauro Giacca, Dónal O’Carroll, Patrick W.F. Hadoke, Laura Denby, Judith C. Sluimer, Andrew H. Baker
Pubblicato in: Circulation Research, Numero 128, 2024, Pagina/e 1258-1275, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.318688

The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing

Autori: Veerle Kremer, Laura Stanicek, Eva van Ingen, Diewertje I. Bink, Sarah Hilderink, Anke J. Tijsen, Ilka Wittig, Lars Mägdefessel, Anne Yaël Nossent, Reinier A. Boon
Pubblicato in: Journal of Cell Science, Numero 135, 2022, ISSN 0021-9533
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jcs.259671

Cardiovascular RNA markers and artificial intelligence may improve COVID-19 outcome: a position paper from the EU-CardioRNA COST Action CA17129

Autori: Lina Badimon, Emma L Robinson, Amela Jusic, Irina Carpusca, Leon J deWindt, Costanza Emanueli, Péter Ferdinandy, Wei Gu, Mariann Gyöngyösi, Matthias Hackl, Kanita Karaduzovic-Hadziabdic, Mitja Lustrek, Fabio Martelli, Eric Nham, Ines Potočnjak, Venkata Satagopam, Reinhard Schneider, Thomas Thum, Yvan Devaux
Pubblicato in: Cardiovascular Research, Numero 117, 2023, Pagina/e 1823-1840, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab094

Persistent <scp>SARS‐CoV</scp>‐2 infection in patients seemingly recovered from <scp>COVID</scp>‐19

Autori: Rossana Bussani, Lorena Zentilin, Ricardo Correa, Andrea Colliva, Furio Silvestri, Serena Zacchigna, Chiara Collesi, Mauro Giacca
Pubblicato in: The Journal of Pathology, Numero 259, 2023, Pagina/e 254-263, ISSN 0022-3417
Editore: John Wiley & Sons Inc.
DOI: 10.1002/path.6035

RNA interference therapeutics for cardiac regeneration

Autori: Josef Huntington, Manendra Pachauri, Hashim Ali and Mauro Giacca
Pubblicato in: Current Opinion in Genetics & Development, 2021, ISSN 1523-3782
Editore: Current Science Inc.
DOI: 10.1016/j.gde.2021.05.007

Development and characterization of anti-fibrotic natural compound similars with improved effectivity

Autori: Fabian Philipp Kreutzer, Anna Meinecke, Saskia Mitzka, Hannah Jill Hunkler, Lisa Hobuß, Naisam Abbas, Robert Geffers, Jan Weusthoff, Ke Xiao, Danny David Jonigk, Jan Fiedler, Thomas Thum
Pubblicato in: Basic Research in Cardiology, Numero 117, 2023, ISSN 0300-8428
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00395-022-00919-6

Reciprocal organ interactions during heart failure: a position paper from the ESCWorking Group on Myocardial Function

Autori: Michele Ciccarelli, Dana Dawson, Ines Falcao-Pires, Mauro Giacca, Nazha Hamdani, Stephane Heymans, Astrid Hooghiemstra, Annebet Leeuwis, Dorien Hermkens, Carlo Gabriele Tocchetti, Jolanda van der Velden, Serena Zacchigna, and Thomas Thum
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab009

COVID19 Impairs Cardiac Function via Endothelial H19 and IL6 Signaling

Autori: Rio P. Juni, Philippa G. Phelp, Diewertje I. Bink, Veerle Kremer, Anke S. van Bergen, Pedro Espinosa Gonzalez, Karlijn B. Rombouts, Karl J. Harber, Daan A.F. Heister, Kak K. Yeung, Jan Van den Bossche, Diederik W.D. Kuster, null null, Paul A.J. Krijnen, Hans W.M. Niessen, Reinier A. Boon
Pubblicato in: Circulation Research, Numero 132, 2024, Pagina/e 648-651, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.122.322166

Gene Therapeutic Strategies for Peripheral Artery Disease and New Opportunities Provided by Adeno-Associated Virus Vectors

Autori: Levon M. Khachigian, Ramon L. Varcoe, Tuisku Suoranta, Nihay Laham-Karam, Seppo Ylä-Herttuala
Pubblicato in: Arteriosclerosis, Thrombosis, and Vascular Biology, Numero 43, 2024, Pagina/e 836-851, ISSN 1079-5642
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.122.318902

Cardiovascular complications of diabetes: role of non-coding RNAs in the crosstalk between immune and cardiovascular systems

Autori: Gaia Spinetti, Martina Mutoli, Simona Greco, Federica Riccio, Soumaya Ben-Aicha, Franziska Kenneweg, Amela Jusic, David de Gonzalo-Calvo, Anne Yaël Nossent, Susana Novella, Georgios Kararigas, Thomas Thum, Costanza Emanueli, Yvan Devaux, Fabio Martelli
Pubblicato in: Cardiovascular Diabetology, Numero 22, 2023, ISSN 1475-2840
Editore: BioMed Central
DOI: 10.1186/s12933-023-01842-3

Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library

Autori: Giulia Ruozi, Francesca Bortolotti, Antonio Mura, Mateusz Tomczyk, Antonella Falcione, Valentina Martinelli, Simone Vodret, Luca Braga, Matteo Dal Ferro, Antonio Cannatà, Lorena Zentilin, Gianfranco Sinagra, Serena Zacchigna, Mauro Giacca
Pubblicato in: Science Translational Medicine, 2022, ISSN 1946-6234
Editore: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abo0699

Gene Therapy for the Heart

Autori: Antonio Cannatà, Hashim Ali, Gianfranco Sinagra, Mauro Giacca
Pubblicato in: Circulation Research, 2020, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.315855

The pathological maelstrom of COVID-19 and cardiovascular disease

Autori: Mauro Giacca, Ajay M. Shah
Pubblicato in: Nature Cardiovascular Research, Numero 1, 2022, Pagina/e 200-210, ISSN 2731-0590
Editore: Nature
DOI: 10.1038/s44161-022-00029-5

Cardiac Regeneration After Myocardial Infarction: an Approachable Goal

Autori: Mauro Giacca
Pubblicato in: Current Cardiology Reports, 2020, ISSN 1523-3782
Editore: Current Science Inc.
DOI: 10.1007/s11886-020-01361-7

Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective

Autori: Laura Santer, Christian Bär, Thomas Thum
Pubblicato in: Molecular Therapy, Numero 27/8, 2019, Pagina/e 1350-1363, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.ymthe.2019.07.001

Gene transfer to the vascular system: Novel translational perspectives for vascular diseases

Autori: A. Remes, D.I. Basha, N. Frey, A.H. Wagner, O.J. Müller
Pubblicato in: Biochemical Pharmacology, Numero 182, 2021, Pagina/e 114265, ISSN 0006-2952
Editore: Elsevier BV
DOI: 10.1016/j.bcp.2020.114265

Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue

Autori: Anca Remes; Dima Ibrahim Basha; Thomas Puehler; Christopher Borowski; Susanne Hille; Laura Kummer; Andreas H. Wagner; Markus Hecker; Jasmin Soethoff; Georg Lutter; Derk Frank; Rawa Arif; Norbert Frey; Marcin Zaradzki; Oliver J. Müller
Pubblicato in: Molecular Therapy. Methods & Clinical Development, Numero 1, 2021, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.omtm.2021.02.017

Omics phenotyping in heart failure: the next frontier

Autori: Antoni Bayes-Genis, Peter P Liu, David E Lanfear, Rudolf A de Boer, Arantxa González, Thomas Thum, Michele Emdin, James L Januzzi
Pubblicato in: European Heart Journal, Numero 41, 2022, Pagina/e 3477-3484, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehaa270

Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function

Autori: Tan Phát Pham, Diewertje I. Bink, Laura Stanicek, Anke van Bergen, Esmee van Leeuwen, Yvonne Tran, Ljubica Matic, Ulf Hedin, Ilka Wittig, Stefanie Dimmeler, Reinier A. Boon
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 8, 2022, ISSN 2296-634X
Editore: Frontiers
DOI: 10.3389/fcell.2020.619079

The LINC00961 transcript and its encoded micropeptide, small regulatory polypeptide of amino acid response, regulate endothelial cell function

Autori: Helen L Spencer, Rachel Sanders, Mounia Boulberdaa, Marco Meloni, Amy Cochrane, Ana-Mishel Spiroski, Joanne Mountford, Costanza Emanueli, Andrea Caporali, Mairi Brittan, Julie Rodor, Andrew H Baker
Pubblicato in: Cardiovascular Research, 2020, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvaa008

Small non-coding RNA therapeutics for cardiovascular disease

Autori: Ajay M. Shah and Mauro Giacca
Pubblicato in: European Heart Journal, 2022, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehac463

RNA-based diagnostic and therapeutic strategies for cardiovascular disease

Autori: Dongchao Lu, Thomas Thum
Pubblicato in: Nature Reviews Cardiology, 2019, ISSN 1759-5002
Editore: Nature Publishing Group
DOI: 10.1038/s41569-019-0218-x

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Autori: D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Lui
Pubblicato in: Nature Communications, Numero 11/1, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-15995-2

Regnase-1 overexpression as a therapeutic approach of Marfan syndrome

Autori: Marie Noormalal, Nesrin Schmiedel, Tarik Bozoglu, Andrea Matzen, Susanne Hille, Dima Ibrahim Basha, Prithviraj Manohar Vijaya Shetty, Anja Wolf, Marcin Zaradzki, Rawa Arif, Thomas Pühler, Georg Lutter, Andreas H. Wagner, Christian Kupatt, Derk Frank, Norbert Frey, Anca Remes, Oliver J. Müller
Pubblicato in: Molecular Therapy - Methods & Clinical Development, Numero 32, 2024, Pagina/e 101163, ISSN 2329-0501
Editore: Molecular Therapy
DOI: 10.1016/j.omtm.2023.101163

Regulation of endogenous cardiomyocyte proliferation: The known unknowns

Autori: Ilaria Secco, Mauro Giacca
Pubblicato in: Journal of Molecular and Cellular Cardiology, Numero 179, 2023, Pagina/e 80-89, ISSN 0022-2828
Editore: Academic Press
DOI: 10.1016/j.yjmcc.2023.04.001

Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function

Autori: Laura Stanicek, Noelia Lozano-Vidal, Diewertje Ilse Bink, Aukie Hooglugt, Wenjie Yao, Ilka Wittig, Jos van Rijssel, Jaap Diederik van Buul, Anke van Bergen, Alina Klems, Anne Sophie Ramms, Ferdinand Le Noble, Patrick Hofmann, Robert Szulcek, ShengPeng Wang, Stefan Offermanns, Meryem Seda Ercanoglu, Hyouk-Bum Kwon, Didier Stainier, Stephan Huveneers, Leo Kurian, Stefanie Dimmeler, Reinier Abraham B
Pubblicato in: Communications Biology, Numero 3/1, 2020, Pagina/e 265, ISSN 2399-3642
Editore: Europe PMC
DOI: 10.1038/s42003-020-0987-0

Cardiac regeneration and remodelling of the cardiomyocyte cytoarchitecture

Autori: Hashim Ali, Luca Braga and Mauro Giacca
Pubblicato in: The FEBS Journal, 2020, ISSN 1742-464X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/febs.15146

Alternative strategies in cardiac preclinical research and new clinical trial formats

Autori: Fabian Philipp Kreutzer, Anna Meinecke, Kevin Schmidt, Jan Fiedler, Thomas Thum
Pubblicato in: Cardiovascular Research, Numero 118, 2022, Pagina/e 746-762, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab075

Non-coding RNA therapeutics for cardiac regeneration

Autori: Luca Braga, Hashim Ali, Ilaria Secco, and Mauro Giacca
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvaa071

RNA- based diagnostic and therapeutic strategies for cardiovascular disease

Autori: Dongchao Lu and Thomas Thum
Pubblicato in: Nature Reviews Cardiology, 2019, ISSN 1759-5002
Editore: Nature Publishing Group
DOI: 10.1038/s41569-019-0218-x

Extracellular Vesicle miRNAs in the Promotion of Cardiac Neovascularisation

Autori: Kesidou D, da Costa Martins PA, de Windt LJ, Brittan M, Beqqali A, Baker AH
Pubblicato in: Frontiers in Physiology, 2020, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.579892

LncRNA AERRIE Is Required for Sulfatase 1 Expression, but Not for Endothelial-to-Mesenchymal Transition

Autori: Tan Phát Pham, Anke S. van Bergen, Veerle Kremer, Simone F. Glaser, Stefanie Dimmeler, Reinier A. Boon
Pubblicato in: International Journal of Molecular Sciences, Numero 22, 2024, Pagina/e 8088, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22158088

Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)

Autori: Rudolf A. de Boer, Stephane Heymans, Johannes Backs, Lucie Carrier, Andrew J.S. Coats, Stefanie Dimmeler, Thomas Eschenhagen, Gerasimos Filippatos, Lior Gepstein, Jean‐Sebastien Hulot, Ralph Knöll, Christian Kupatt, Wolfgang A. Linke, Christine E. Seidman, C. Gabriele Tocchetti, Jolanda van der Velden, Roddy Walsh, Petar M. Seferovic, Thomas Thum
Pubblicato in: European Journal of Heart Failure, Numero 24, 2023, Pagina/e 406-420, ISSN 1388-9842
Editore: Elsevier BV
DOI: 10.1002/ejhf.2414

Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression

Autori: Noelia Lozano-Vidal, Laura Stanicek, Diewertje I. Bink, Rio P. Juni, Aukie Hooglugt, Veerle Kremer, Philippa Phelp, Anke van Bergen, Alyson W. MacInnes, Stefanie Dimmeler, Reinier A. Boon
Pubblicato in: Communications Biology, Numero 7, 2024, ISSN 2399-3642
Editore: Communications Biology
DOI: 10.1038/s42003-024-06230-5

AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses

Autori: Henna Korpela, Jaakko Lampela, Jonna Airaksinen, Niko Järveläinen, Satu Siimes, Kaisa Valli, Tiina Nieminen, Minttu Turunen, Maria Grönman, Antti Saraste, Juhani Knuuti, Mikko Hakulinen, Pekka Poutiainen, Vesa Kärjä, Jussi Nurro and Seppo Ylä-Herttuala
Pubblicato in: Gene Therapy, 2022, ISSN 0969-7128
Editore: Nature Publishing Group
DOI: 10.1038/s41434-022-00322-9

Human AdV-20-42-42, a Promising Novel Adenoviral Vector for Gene Therapy and Vaccine Product Development

Autori: Mónika Z Ballmann 1 , Svjetlana Raus 2 , Ruben Engelhart 1 2 , Győző L Kaján 3 , Abdelaziz Beqqali 2 , Patrick W F Hadoke 2 , Chantal van der Zalm 1 , Tibor Papp 4 , Lijo John 3 , Selina Khan 4 , Satish Boedhoe 4 , Katarina Danskog 3 , Lars Frängsmyr 3 , Jerome Custers 4 , Wilfried A M Bakker 1 , Hilde M van der Schaar 1 , Niklas Arnberg 3 , Angelique A C Lemckert 1 , Menz
Pubblicato in: Journal of Virology, Numero Oct 27;95(22):e0038721, 2021, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/jvi.00387-21

Cell-Specific Targeting of the Endothelium in the CardioRenal Syndrome

Autori: Nihay Laham-Karam, Johanna P. Laakkonen, Seppo Yla-Herttuala, Annayya Aroor, Guanghong Jia, Adam Whaley-Connell
Pubblicato in: Cardiorenal Medicine, 2024, ISSN 1664-3828
Editore: S. Karger AG
DOI: 10.1159/000537764

MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium

Autori: Veerle Kremer, Diewertje I. Bink, Laura Stanicek, Eva van Ingen, Theresa Gimbel, Sarah Hilderink, Stefan Günther, Anne Yaël Nossent, Reinier A. Boon
Pubblicato in: Scientific Reports, Numero 12, 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-04812-z

Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease.

Autori: Cheng-Kai Huang; Sabine Kafert-Kasting; Thomas Thum
Pubblicato in: Circulation Research, Numero 2, 2020, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.315856

The Influence of the LINC00961/SPAAR Locus Loss on Murine Development, Myocardial Dynamics, and Cardiac Response to Myocardial Infarction

Autori: Spiroski AM, Sanders R, Meloni M, McCracken IR, Thomson A, Brittan M, Gray GA, Baker AH
Pubblicato in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22020969

Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells

Autori: Rahul Mallick, Erika Gurzeler, Pyry I. Toivanen, Tiina Nieminen, Seppo Ylä-Herttuala
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Numero 10, 2022, ISSN 2296-4185
Editore: Frontiers
DOI: 10.3389/fbioe.2022.907538

Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function

Autori: 12) Serena Zacchigna, Alessia Paldino, Ines Falcao-Pires, Evangelos P. Daskalopoulos,Matteo Dal Ferro, Simone Vodret, Pierluigi Lesizza, Antonio Cannata, Daniela Miranda-Silva, Andre P. Lourenc, Bruno Pinamonti, Gianfranco Sinagra, FlorianWeinberger, Thomas Eschenhagen, Lucie Carrier, Izhak Kehat, Carlo G. Tocchetti, Michele Russo, Alessandra Ghigo, James Cimino, Emilio Hirsch, Dana Dawson, Michel
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvaa110

Targeting muscle-enriched long non-coding RNA <i>H19</i> reverses pathological cardiac hypertrophy

Autori: Janika Viereck, Anne Bührke, Ariana Foinquinos, Shambhabi Chatterjee, Jan A Kleeberger, Ke Xiao, Heike Janssen-Peters, Sandor Batkai, Deepak Ramanujam, Theresia Kraft, Serghei Cebotari, Faikah Gueler, Andreas M Beyer, Jessica Schmitz, Jan H Bräsen, Jan D Schmitto, Mariann Gyöngyösi, Alexandra Löser, Marc N Hirt, Thomas Eschenhagen, Stefan Engelhardt, Christian Bär, Thomas Thum
Pubblicato in: European Heart Journal, Numero 41, 2022, Pagina/e 3462-3474, ISSN 0195-668X
Editore: Oxford University Press
DOI: 10.1093/eurheartj/ehaa519

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TREATMENT

Numero candidatura/pubblicazione: 20 23052170
Data: 2023-08-18
Candidato/i: THE UNIVERSITY OF EDINBURGH

ADENOVIRUS VECTORS AND USES THEREOF

Numero candidatura/pubblicazione: 20 786618
Data: 2020-10-02
Candidato/i: BATAVIA BIOSCIENCES BV

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