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individualizedPaediatricCure: Cloud-based virtual-patient models for precision paediatric oncology

Project description

Virtual mechanistic modelling to predict personalised therapies for paediatric cancers

The EU-funded iPC project is developing a personalised medicine approach for children with cancer, focussing on high-incidence and high-risk paediatric tumours. This computational effort will combine knowledge-based, machine-learning and mechanistic models to predict optimal standard and experimental therapies for each child. The approach is based on virtual patient models whose analysis will inform personalised diagnostics and recommend treatments. The consortium comprises experts in basic, translational and clinical research, and it has established strong relationships with prestigious patient organisations and clinical trials focussed on personalised medicine for the proposed case studies.

Call for proposal

H2020-SC1-DTH-2018-2020

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Sub call

H2020-SC1-DTH-2018-1

Coordinator

TECHNIKON FORSCHUNGS- UND PLANUNGSGESELLSCHAFT MBH
Net EU contribution
€ 513 004,90
Address
Burgplatz 3a
9500 Villach
Austria

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Region
Südösterreich Kärnten Klagenfurt-Villach
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Participants (22)

IBM RESEARCH GMBH
Switzerland
Net EU contribution
€ 2 020 506,73
Address
Saeumerstrasse 4
8803 Rueschlikon

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
BAYLOR COLLEGE OF MEDICINE
United States
Net EU contribution
€ 1 104 991,11
Address
One Baylor Plaza T119
77030 Houston Tx

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUT CURIE
France
Net EU contribution
€ 1 381 550,34
Address
Rue D'ulm 26
75231 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
TECHNISCHE UNIVERSITAT DARMSTADT
Germany
Net EU contribution
€ 720 673,46
Address
Karolinenplatz 5
64289 Darmstadt

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Region
Darmstadt Darmstadt, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Italy
Net EU contribution
€ 482 857,45
Address
Corso Umberto I, 40
80138 Napoli

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Region
Sud Campania Napoli
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITEIT GENT
Belgium
Net EU contribution
€ 668 974,33
Address
Sint Pietersnieuwstraat 25
9000 Gent

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Region
Vlaams Gewest Prov. Oost-Vlaanderen Arr. Gent
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
BARCELONA SUPERCOMPUTING CENTER CENTRO NACIONAL DE SUPERCOMPUTACION
Spain
Net EU contribution
€ 970 554,74
Address
Calle Jordi Girona 31
08034 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
Net EU contribution
€ 41 110,15
Address
Carrer Doctor Aiguader 88
08003 Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
XLAB RAZVOJ PROGRAMSKE OPREME IN SVETOVANJE DOO
Slovenia
Net EU contribution
€ 369 243,94
Address
Pot Za Brdom 100
1000 Ljubljana

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
PRINSES MAXIMA CENTRUM VOOR KINDERONCOLOGIE BV
Netherlands
Net EU contribution
€ 629 109,94
Address
Heidelberglaan 25
3584CS Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Other
Other funding
€ 0,00
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany
Net EU contribution
€ 769 881,06
Address
Hofgartenstrasse 8
80539 Munchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Research Organisations
Other funding
€ 0,00
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
Net EU contribution
€ 437 262,55
Address
Meibergdreef 15
1105AZ Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
Net EU contribution
€ 421 500,00
Address
Im Neuenheimer Feld 672
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
INSTITUT DE INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL
Spain
Net EU contribution
€ 397 398,16
Address
Ctra De Canyet S/n
08916 Badalona Barcelona

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Region
Este Cataluña Barcelona
Activity type
Research Organisations
Other funding
€ 0,00
ALACRIS THERANOSTICS GMBH
Germany
Net EU contribution
€ 861 444,60
Address
Max Planck Strasse 3
12489 Berlin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Berlin Berlin Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITAT ZURICH
Switzerland
Net EU contribution
€ 1 451 213,36
Address
Ramistrasse 71
8006 Zurich

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Region
Schweiz/Suisse/Svizzera Zürich Zürich
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany
Net EU contribution
€ 531 691,33
Address
Im Neuenheimer Feld 280
69120 Heidelberg

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Activity type
Research Organisations
Other funding
€ 0,00
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 414 838,83
Address
Geschwister Scholl Platz 1
80539 Muenchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
THE CHILDREN'S HOSPITAL OF PHILADELPHIA NON PROFIT ORG
United States
Net EU contribution
€ 175 652,48
Other funding
€ 0,00
CONSIGLIO NAZIONALE DELLE RICERCHE
Italy
Net EU contribution
€ 384 940,54
Address
Piazzale Aldo Moro 7
00185 Roma

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Other funding
€ 0,00
CHILDREN'S MEDICAL RESEARCH INSTITUTE
Australia
Net EU contribution
€ 0,00
Address
214 Hawkesbury Road
2145 Westmead, New South Wales

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Activity type
Research Organisations
Other funding
€ 318 125,00
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
Net EU contribution
€ 0,00
Address
Chariteplatz 1
10117 Berlin

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Region
Berlin Berlin Berlin
Activity type
Higher or Secondary Education Establishments
Other funding
€ 93 326,00