Advanced and versatile PRInting platform for the next generation of active Microfluidic dEvices

Livrables

Printable materials with photomechanical response (public version)

Report including general considerations on synthetic procedures and performance of materials

Printed sensing functions (public version)

Report including basic conceptual principle of the sensing elements in a microfludic device and performance characterization

Printed actuating functions (public version)

Report including basic conceptual principle of the light activated fluidic elements in a microfludic device and performance characterization

Validated prototype of the OoC

Report including basic conceptual principle and performance characterization of the light actuated chip as an OoC device

Sensing printable materials (public version)

Report including general considerations on synthetic procedures for printable materials for sensing and nanoparticles and performance of materials

Dissemination event for stakeholders interested in PRIME's technology

Report on the dissemination event for stakeholders interested in PRIMEs technology

First printed sensing functions (public version)

Report including the basic conceptual principle of the sensing elements and performance characterization

Communication and Dissemination strategy

Report on the comprehensive Communication and Dissemination strategy of the project to ensure that all generated knowledge will be successfully transmitted to the right target groups throughout the project.

First printed actuating functions (public version)

Report including the basic conceptual principle of the light activated first printed fluidic elements and performance characterization

Validated prototype of the IVD chip

Report including basic conceptual principle and performance characterization of the light actuated chip as an IVD device

Website

PRIMEs web portal to be constantly maintained and updated

Data management plan

Good-practice data management plan for the project.

Publications

Photonic and magnetic materials for on-demand local drug delivery

Auteurs: Ilaria Armenia; Carlos Cuestas Ayllón; Beatriz Torres Herrero; Francesca Bussolari; Gabriel Alfranca; Valeria Grazú; Jesús Martínez de la Fuente
Publié dans: Advanced Drug Delivery Reviews, Numéro 191, 2022, ISSN 1872-8294
Éditeur: Elsevier B.V.
DOI: 10.1016/j.addr.2022.114584

Direct Ink Writing of Recyclable Supramolecular Soft Actuators

Auteurs: Lugger, Sean J. D.; Verbroekken, Ruth M. C.; Mulder, Dirk J.; Schenning, Albert P. H. J.
Publié dans: ACS Macro Letters, Numéro 3, 2022, Page(s) 935-940, ISSN 2161-1653
Éditeur: American Chemical Society
DOI: 10.1021/acsmacrolett.2c00359

Melt-Extruded Thermoplastic Liquid Crystal Elastomer Rotating Fiber Actuators

Auteurs: Sean J. D. Lugger, Tom A. P. Engels, Ruth Cardinaels, Tom Bus, Dirk J. Mulder, Albert P.H.J. Schenning
Publié dans: Advanced functional materials, Numéro 33, 49, 2023, Page(s) 2306853, ISSN 1616-301X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202306853

Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

Auteurs: Laura Paz-Artigas, Sandra González-Lana, Nicolás Polo, Pedro Vicente, Pilar Montero-Calle, Miguel A. Martínez, Gregorio Rábago, Margarida Serra, Felipe Prósper, Manuel M. Mazo, Arantxa González, Ignacio Ochoa, Jesús Ciriza
Publié dans: ACS Biomaterials Science & Engineering, 2024, ISSN 2373-9878
Éditeur: American Chemical Society
DOI: 10.1021/acsbiomaterials.3c01302

One-pot Synthesis of Melt-Processable Supramolecular Soft Actuators

Auteurs: Sean J. D. Lugger, Dirk J. Mulder, Albertus P. H. J. Schenning
Publié dans: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202115166

Current approaches for the recreation of cardiac ischaemic environment in vitro

Auteurs: Paz-Artigas, L. (Laura); Montero, P. (Pilar); Iglesias-García, O. (Olalla); Mazo, M. (Manuel); Ochoa, I. (Ignacio); Ciriza, J. (Jesús)
Publié dans: International Journal of Pharmaceutics, Numéro 1, 2023, ISSN 1873-3476
Éditeur: Elsevier

Self‐sealing thermoplastic fluoroelastomer enables rapid fabrication of modular microreactors

Auteurs: Alexander H. McMillan; Juan Mora-Macías; Joan Teyssandier; Raymond Thür; Emmanuel Roy; Ignacio Ochoa; Steven De Feyter; Ivo F.J. Vankelecom; Maarten B. J. Roeffaers; Sasha Cai Lesher-Perez
Publié dans: Nano Select, Vol 2, Iss 7, Pp 1385-1402 (2021), Numéro 3, 2021, ISSN 2688-4011
Éditeur: Willey-VCH GmbH
DOI: 10.1002/nano.202000241

Melt electrowriting of liquid crystal elastomer scaffolds with programmed mechanical response

Auteurs: Mehrzad Javadzadeh; Jesus del Barrio; Carlos Sánchez Somolinos
Publié dans: Advanced materials, Numéro 35-14, 2023, Page(s) art number 2209244, ISSN 0935-9648
Éditeur: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202209244

Photomechanical response under physiological conditions of azobenzene-containing 4D-printed liquid crystal elastomer actuators

Auteurs: Lorena Ceamanos, Dirk J. Mulder, Zehra Kahveci, María López-Valdeolivas, Albert P.H.J. Schenning, Carlos Sánchez Somolinos
Publié dans: Journal of Materials Chemistry B, Numéro 11 (18), 2023, Page(s) 4083-4094, ISSN 2050-750X
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2tb02757g

Fully (Re)configurable Interactive Material through a Switchable Photothermal Charge Transfer Complex Gated by a Supramolecular Liquid Crystal Elastomer Actuator

Auteurs: Shuang Tian, Sean J. D. Lugger, Chun-Sing Lee, Michael G. Debije, Albert P. H. J. Schenning
Publié dans: J. Am. Chem. Soc., Numéro 145, 35, 2023, Page(s) 19347-19353, ISSN 0002-7863
Éditeur: American Chemical Society
DOI: 10.1021/jacs.3c05905

From cells to form: A roadmap to study shape emergence in vivo

Auteurs: Ana Patricia Ramos; Alicja Szalapak; Lucrezia Camilla Ferme; Carl D. Modes
Publié dans: Biophysical Journal, Numéro 122, 18, 2023, Page(s) 3587-3599, ISSN 1542-0086
Éditeur: Cell Press
DOI: 10.1016/j.bpj.2023.05.015

Hydrogen-Bonded Supramolecular Liquid Crystal Polymers: Smart Materials with Stimuli-Responsive, Self-Healing, and Recyclable Properties

Auteurs: Sean J. D. Lugger, Simon J. A. Houben, Yari Foelen, Michael G. Debije, Albert P. H. J. Schenning, Dirk J. Mulder
Publié dans: Chemical Reviews, 2021, ISSN 0009-2665
Éditeur: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00330

4D Printing of Supramolecular Liquid Crystal Elastomer Actuators Fueled by Light

Auteurs: Lugger, Sean J. D.; Ceamanos, Lorena; Mulder, Dirk Jan; Sánchez-Somolinos, Carlos; Schenning, Albert P. H. J.
Publié dans: Advanced materials technologies, Numéro 5, 2022, Page(s) 2201472, ISSN 2365-709X
Éditeur: Wiley-Blackwell
DOI: 10.1002/admt.202201472

Surface modifications of COP-based microfluidic devices for improved immobilisation of hydrogel proteins: long-term 3D culture with contractile cell types and ischaemia model

Auteurs: Sandra González-Lana, Teodora Randelovic, Jesús Ciriza, María López-Valdeolivas, Rosa Monge, Carlos Sánchez Somolinos, Ignacio Ochoa
Publié dans: Lab on a Chip, 2023, Page(s) 2434-2446, ISSN 1473-0197
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3lc00075c

Towards novel biomimetic in vitro models of the blood-brain barrier for drug permeability evaluation

Auteurs: Mármol, Inés; Abizanda-Campo, Sara; Ayuso, José M.; Ochoa, Ignacio; Oliván, Sara
Publié dans: Bioengineering, Numéro 10, 2023, ISSN 2306-5354
Éditeur: MDPI

In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

Auteurs: Tijana Stankovića, Teodora Ranđelović, Miodrag Dragoj, Sonja Stojković Burić, LuisFernández, Ignacio Ochoa, Victor M.Pérez-García, MilicaPešić
Publié dans: Drug Resistance Updates, 2021, ISSN 1368-7646
Éditeur: Churchill Livingstone
DOI: 10.1016/j.drup.2021.100753

Reprogrammable 4D printed liquid crystal elastomer photoactuators by means of light-resersible perylene diimide radicals

Auteurs: Lorena Montesino, Jesus I. Martinez, C. Sanchez Somolinos
Publié dans: Advanced functional materials, 2023, ISSN 1616-301X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202309019

Thermal Paper and Time Temperature Integrators Made From a Structural Colored Polymer Crosslinked With Hydrogen Bonded Cyclohexanoic Acid Derivatives

Auteurs: Foelen, Yari; van der Heijden, Daniëlle A. C.; Verdurmen, Anne M. J.; Mulder, Dirk J.; Lub, Johan; Schenning, Albert P. H. J.
Publié dans: Advanced optical materials, Numéro 1, 2022, Page(s) 2201462, ISSN 2195-1071
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/adom.202201462

Four-Dimensional Printed Liquid Crystalline Elastomer Actuators with Fast Photoinduced Mechanical Response toward Light-Driven Robotic Functions

Auteurs: Lorena Ceamanos, Zehra Kahveci, María López-Valdeolivas, Danqing Liu, Dirk Jan Broer, Carlos Sánchez-Somolinos
Publié dans: ACS Applied Materials & Interfaces, Numéro 12/39, 2020, Page(s) 44195-44204, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.0c13341

Livrables

Publications

Partager cette page

Télécharger