Advanced and versatile PRInting platform for the next generation of active Microfluidic dEvices

Informacje na temat projektu

PRIME

Identyfikator umowy o grant: 829010

DOI

10.3030/829010

Projekt został zamknięty

Data podpisania przez KE 17 Grudnia 2018

Data rozpoczęcia 1 Maja 2019

Data zakończenia 31 Października 2023

Finansowanie w ramach

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Koszt całkowity

€ 2 820 991,25

Wkład UE

€ 2 820 991,25

Koordynowany przez

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (10)

Printable materials with photomechanical response (public version)

Report including general considerations on synthetic procedures and performance of materials

Printed sensing functions (public version)

Report including basic conceptual principle of the sensing elements in a microfludic device and performance characterization

Printed actuating functions (public version)

Report including basic conceptual principle of the light activated fluidic elements in a microfludic device and performance characterization

Validated prototype of the OoC

Report including basic conceptual principle and performance characterization of the light actuated chip as an OoC device

Sensing printable materials (public version)

Report including general considerations on synthetic procedures for printable materials for sensing and nanoparticles and performance of materials

Dissemination event for stakeholders interested in PRIME's technology

Report on the dissemination event for stakeholders interested in PRIMEs technology

First printed sensing functions (public version)

Report including the basic conceptual principle of the sensing elements and performance characterization

Communication and Dissemination strategy

Report on the comprehensive Communication and Dissemination strategy of the project to ensure that all generated knowledge will be successfully transmitted to the right target groups throughout the project.

First printed actuating functions (public version)

Report including the basic conceptual principle of the light activated first printed fluidic elements and performance characterization

Validated prototype of the IVD chip

Report including basic conceptual principle and performance characterization of the light actuated chip as an IVD device

Websites, patent fillings, videos etc. (1)

Website

PRIMEs web portal to be constantly maintained and updated

Open Research Data Pilot (1)

Data management plan

Good-practice data management plan for the project.

Publikacje

Peer reviewed articles (19)

Photonic and magnetic materials for on-demand local drug delivery

Autorzy: Ilaria Armenia; Carlos Cuestas Ayllón; Beatriz Torres Herrero; Francesca Bussolari; Gabriel Alfranca; Valeria Grazú; Jesús Martínez de la Fuente
Opublikowane w: Advanced Drug Delivery Reviews, Numer 191, 2022, ISSN 1872-8294
Wydawca: Elsevier B.V.
DOI: 10.1016/j.addr.2022.114584

Direct Ink Writing of Recyclable Supramolecular Soft Actuators

Autorzy: Lugger, Sean J. D.; Verbroekken, Ruth M. C.; Mulder, Dirk J.; Schenning, Albert P. H. J.
Opublikowane w: ACS Macro Letters, Numer 3, 2022, Strona(/y) 935-940, ISSN 2161-1653
Wydawca: American Chemical Society
DOI: 10.1021/acsmacrolett.2c00359

Melt-Extruded Thermoplastic Liquid Crystal Elastomer Rotating Fiber Actuators

Autorzy: Sean J. D. Lugger, Tom A. P. Engels, Ruth Cardinaels, Tom Bus, Dirk J. Mulder, Albert P.H.J. Schenning
Opublikowane w: Advanced functional materials, Numer 33, 49, 2023, Strona(/y) 2306853, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202306853

Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

Autorzy: Laura Paz-Artigas, Sandra González-Lana, Nicolás Polo, Pedro Vicente, Pilar Montero-Calle, Miguel A. Martínez, Gregorio Rábago, Margarida Serra, Felipe Prósper, Manuel M. Mazo, Arantxa González, Ignacio Ochoa, Jesús Ciriza
Opublikowane w: ACS Biomaterials Science & Engineering, 2024, ISSN 2373-9878
Wydawca: American Chemical Society
DOI: 10.1021/acsbiomaterials.3c01302

One-pot Synthesis of Melt-Processable Supramolecular Soft Actuators

Autorzy: Sean J. D. Lugger, Dirk J. Mulder, Albertus P. H. J. Schenning
Opublikowane w: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202115166

Current approaches for the recreation of cardiac ischaemic environment in vitro

Autorzy: Paz-Artigas, L. (Laura); Montero, P. (Pilar); Iglesias-García, O. (Olalla); Mazo, M. (Manuel); Ochoa, I. (Ignacio); Ciriza, J. (Jesús)
Opublikowane w: International Journal of Pharmaceutics, Numer 1, 2023, ISSN 1873-3476
Wydawca: Elsevier

Self‐sealing thermoplastic fluoroelastomer enables rapid fabrication of modular microreactors

Autorzy: Alexander H. McMillan; Juan Mora-Macías; Joan Teyssandier; Raymond Thür; Emmanuel Roy; Ignacio Ochoa; Steven De Feyter; Ivo F.J. Vankelecom; Maarten B. J. Roeffaers; Sasha Cai Lesher-Perez
Opublikowane w: Nano Select, Vol 2, Iss 7, Pp 1385-1402 (2021), Numer 3, 2021, ISSN 2688-4011
Wydawca: Willey-VCH GmbH
DOI: 10.1002/nano.202000241

Melt electrowriting of liquid crystal elastomer scaffolds with programmed mechanical response

Autorzy: Mehrzad Javadzadeh; Jesus del Barrio; Carlos Sánchez Somolinos
Opublikowane w: Advanced materials, Numer 35-14, 2023, Strona(/y) art number 2209244, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202209244

Photomechanical response under physiological conditions of azobenzene-containing 4D-printed liquid crystal elastomer actuators

Autorzy: Lorena Ceamanos, Dirk J. Mulder, Zehra Kahveci, María López-Valdeolivas, Albert P.H.J. Schenning, Carlos Sánchez Somolinos
Opublikowane w: Journal of Materials Chemistry B, Numer 11 (18), 2023, Strona(/y) 4083-4094, ISSN 2050-750X
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2tb02757g

Fully (Re)configurable Interactive Material through a Switchable Photothermal Charge Transfer Complex Gated by a Supramolecular Liquid Crystal Elastomer Actuator

Autorzy: Shuang Tian, Sean J. D. Lugger, Chun-Sing Lee, Michael G. Debije, Albert P. H. J. Schenning
Opublikowane w: J. Am. Chem. Soc., Numer 145, 35, 2023, Strona(/y) 19347-19353, ISSN 0002-7863
Wydawca: American Chemical Society
DOI: 10.1021/jacs.3c05905

From cells to form: A roadmap to study shape emergence in vivo

Autorzy: Ana Patricia Ramos; Alicja Szalapak; Lucrezia Camilla Ferme; Carl D. Modes
Opublikowane w: Biophysical Journal, Numer 122, 18, 2023, Strona(/y) 3587-3599, ISSN 1542-0086
Wydawca: Cell Press
DOI: 10.1016/j.bpj.2023.05.015

Hydrogen-Bonded Supramolecular Liquid Crystal Polymers: Smart Materials with Stimuli-Responsive, Self-Healing, and Recyclable Properties

Autorzy: Sean J. D. Lugger, Simon J. A. Houben, Yari Foelen, Michael G. Debije, Albert P. H. J. Schenning, Dirk J. Mulder
Opublikowane w: Chemical Reviews, 2021, ISSN 0009-2665
Wydawca: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00330

4D Printing of Supramolecular Liquid Crystal Elastomer Actuators Fueled by Light

Autorzy: Lugger, Sean J. D.; Ceamanos, Lorena; Mulder, Dirk Jan; Sánchez-Somolinos, Carlos; Schenning, Albert P. H. J.
Opublikowane w: Advanced materials technologies, Numer 5, 2022, Strona(/y) 2201472, ISSN 2365-709X
Wydawca: Wiley-Blackwell
DOI: 10.1002/admt.202201472

Surface modifications of COP-based microfluidic devices for improved immobilisation of hydrogel proteins: long-term 3D culture with contractile cell types and ischaemia model

Autorzy: Sandra González-Lana, Teodora Randelovic, Jesús Ciriza, María López-Valdeolivas, Rosa Monge, Carlos Sánchez Somolinos, Ignacio Ochoa
Opublikowane w: Lab on a Chip, 2023, Strona(/y) 2434-2446, ISSN 1473-0197
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3lc00075c

Towards novel biomimetic in vitro models of the blood-brain barrier for drug permeability evaluation

Autorzy: Mármol, Inés; Abizanda-Campo, Sara; Ayuso, José M.; Ochoa, Ignacio; Oliván, Sara
Opublikowane w: Bioengineering, Numer 10, 2023, ISSN 2306-5354
Wydawca: MDPI

In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

Autorzy: Tijana Stankovića, Teodora Ranđelović, Miodrag Dragoj, Sonja Stojković Burić, LuisFernández, Ignacio Ochoa, Victor M.Pérez-García, MilicaPešić
Opublikowane w: Drug Resistance Updates, 2021, ISSN 1368-7646
Wydawca: Churchill Livingstone
DOI: 10.1016/j.drup.2021.100753

Reprogrammable 4D printed liquid crystal elastomer photoactuators by means of light-resersible perylene diimide radicals

Autorzy: Lorena Montesino, Jesus I. Martinez, C. Sanchez Somolinos
Opublikowane w: Advanced functional materials, 2023, ISSN 1616-301X
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202309019

Thermal Paper and Time Temperature Integrators Made From a Structural Colored Polymer Crosslinked With Hydrogen Bonded Cyclohexanoic Acid Derivatives

Autorzy: Foelen, Yari; van der Heijden, Daniëlle A. C.; Verdurmen, Anne M. J.; Mulder, Dirk J.; Lub, Johan; Schenning, Albert P. H. J.
Opublikowane w: Advanced optical materials, Numer 1, 2022, Strona(/y) 2201462, ISSN 2195-1071
Wydawca: Wiley-VCH GmbH
DOI: 10.1002/adom.202201462

Four-Dimensional Printed Liquid Crystalline Elastomer Actuators with Fast Photoinduced Mechanical Response toward Light-Driven Robotic Functions

Autorzy: Lorena Ceamanos, Zehra Kahveci, María López-Valdeolivas, Danqing Liu, Dirk Jan Broer, Carlos Sánchez-Somolinos
Opublikowane w: ACS Applied Materials & Interfaces, Numer 12/39, 2020, Strona(/y) 44195-44204, ISSN 1944-8244
Wydawca: American Chemical Society
DOI: 10.1021/acsami.0c13341