Advanced and versatile PRInting platform for the next generation of active Microfluidic dEvices

Leistungen

Printable materials with photomechanical response (public version)

Report including general considerations on synthetic procedures and performance of materials

Printed sensing functions (public version)

Report including basic conceptual principle of the sensing elements in a microfludic device and performance characterization

Printed actuating functions (public version)

Report including basic conceptual principle of the light activated fluidic elements in a microfludic device and performance characterization

Validated prototype of the OoC

Report including basic conceptual principle and performance characterization of the light actuated chip as an OoC device

Sensing printable materials (public version)

Report including general considerations on synthetic procedures for printable materials for sensing and nanoparticles and performance of materials

Dissemination event for stakeholders interested in PRIME's technology

Report on the dissemination event for stakeholders interested in PRIMEs technology

First printed sensing functions (public version)

Report including the basic conceptual principle of the sensing elements and performance characterization

Communication and Dissemination strategy

Report on the comprehensive Communication and Dissemination strategy of the project to ensure that all generated knowledge will be successfully transmitted to the right target groups throughout the project.

First printed actuating functions (public version)

Report including the basic conceptual principle of the light activated first printed fluidic elements and performance characterization

Validated prototype of the IVD chip

Report including basic conceptual principle and performance characterization of the light actuated chip as an IVD device

Website

PRIMEs web portal to be constantly maintained and updated

Data management plan

Good-practice data management plan for the project.

Veröffentlichungen

Photonic and magnetic materials for on-demand local drug delivery

Autoren: Ilaria Armenia; Carlos Cuestas Ayllón; Beatriz Torres Herrero; Francesca Bussolari; Gabriel Alfranca; Valeria Grazú; Jesús Martínez de la Fuente
Veröffentlicht in: Advanced Drug Delivery Reviews, Ausgabe 191, 2022, ISSN 1872-8294
Herausgeber: Elsevier B.V.
DOI: 10.1016/j.addr.2022.114584

Direct Ink Writing of Recyclable Supramolecular Soft Actuators

Autoren: Lugger, Sean J. D.; Verbroekken, Ruth M. C.; Mulder, Dirk J.; Schenning, Albert P. H. J.
Veröffentlicht in: ACS Macro Letters, Ausgabe 3, 2022, Seite(n) 935-940, ISSN 2161-1653
Herausgeber: American Chemical Society
DOI: 10.1021/acsmacrolett.2c00359

Melt-Extruded Thermoplastic Liquid Crystal Elastomer Rotating Fiber Actuators

Autoren: Sean J. D. Lugger, Tom A. P. Engels, Ruth Cardinaels, Tom Bus, Dirk J. Mulder, Albert P.H.J. Schenning
Veröffentlicht in: Advanced functional materials, Ausgabe 33, 49, 2023, Seite(n) 2306853, ISSN 1616-301X
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202306853

Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

Autoren: Laura Paz-Artigas, Sandra González-Lana, Nicolás Polo, Pedro Vicente, Pilar Montero-Calle, Miguel A. Martínez, Gregorio Rábago, Margarida Serra, Felipe Prósper, Manuel M. Mazo, Arantxa González, Ignacio Ochoa, Jesús Ciriza
Veröffentlicht in: ACS Biomaterials Science & Engineering, 2024, ISSN 2373-9878
Herausgeber: American Chemical Society
DOI: 10.1021/acsbiomaterials.3c01302

One-pot Synthesis of Melt-Processable Supramolecular Soft Actuators

Autoren: Sean J. D. Lugger, Dirk J. Mulder, Albertus P. H. J. Schenning
Veröffentlicht in: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202115166

Current approaches for the recreation of cardiac ischaemic environment in vitro

Autoren: Paz-Artigas, L. (Laura); Montero, P. (Pilar); Iglesias-García, O. (Olalla); Mazo, M. (Manuel); Ochoa, I. (Ignacio); Ciriza, J. (Jesús)
Veröffentlicht in: International Journal of Pharmaceutics, Ausgabe 1, 2023, ISSN 1873-3476
Herausgeber: Elsevier

Self‐sealing thermoplastic fluoroelastomer enables rapid fabrication of modular microreactors

Autoren: Alexander H. McMillan; Juan Mora-Macías; Joan Teyssandier; Raymond Thür; Emmanuel Roy; Ignacio Ochoa; Steven De Feyter; Ivo F.J. Vankelecom; Maarten B. J. Roeffaers; Sasha Cai Lesher-Perez
Veröffentlicht in: Nano Select, Vol 2, Iss 7, Pp 1385-1402 (2021), Ausgabe 3, 2021, ISSN 2688-4011
Herausgeber: Willey-VCH GmbH
DOI: 10.1002/nano.202000241

Melt electrowriting of liquid crystal elastomer scaffolds with programmed mechanical response

Autoren: Mehrzad Javadzadeh; Jesus del Barrio; Carlos Sánchez Somolinos
Veröffentlicht in: Advanced materials, Ausgabe 35-14, 2023, Seite(n) art number 2209244, ISSN 0935-9648
Herausgeber: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202209244

Photomechanical response under physiological conditions of azobenzene-containing 4D-printed liquid crystal elastomer actuators

Autoren: Lorena Ceamanos, Dirk J. Mulder, Zehra Kahveci, María López-Valdeolivas, Albert P.H.J. Schenning, Carlos Sánchez Somolinos
Veröffentlicht in: Journal of Materials Chemistry B, Ausgabe 11 (18), 2023, Seite(n) 4083-4094, ISSN 2050-750X
Herausgeber: Royal Society of Chemistry
DOI: 10.1039/d2tb02757g

Fully (Re)configurable Interactive Material through a Switchable Photothermal Charge Transfer Complex Gated by a Supramolecular Liquid Crystal Elastomer Actuator

Autoren: Shuang Tian, Sean J. D. Lugger, Chun-Sing Lee, Michael G. Debije, Albert P. H. J. Schenning
Veröffentlicht in: J. Am. Chem. Soc., Ausgabe 145, 35, 2023, Seite(n) 19347-19353, ISSN 0002-7863
Herausgeber: American Chemical Society
DOI: 10.1021/jacs.3c05905

From cells to form: A roadmap to study shape emergence in vivo

Autoren: Ana Patricia Ramos; Alicja Szalapak; Lucrezia Camilla Ferme; Carl D. Modes
Veröffentlicht in: Biophysical Journal, Ausgabe 122, 18, 2023, Seite(n) 3587-3599, ISSN 1542-0086
Herausgeber: Cell Press
DOI: 10.1016/j.bpj.2023.05.015

Hydrogen-Bonded Supramolecular Liquid Crystal Polymers: Smart Materials with Stimuli-Responsive, Self-Healing, and Recyclable Properties

Autoren: Sean J. D. Lugger, Simon J. A. Houben, Yari Foelen, Michael G. Debije, Albert P. H. J. Schenning, Dirk J. Mulder
Veröffentlicht in: Chemical Reviews, 2021, ISSN 0009-2665
Herausgeber: American Chemical Society
DOI: 10.1021/acs.chemrev.1c00330

4D Printing of Supramolecular Liquid Crystal Elastomer Actuators Fueled by Light

Autoren: Lugger, Sean J. D.; Ceamanos, Lorena; Mulder, Dirk Jan; Sánchez-Somolinos, Carlos; Schenning, Albert P. H. J.
Veröffentlicht in: Advanced materials technologies, Ausgabe 5, 2022, Seite(n) 2201472, ISSN 2365-709X
Herausgeber: Wiley-Blackwell
DOI: 10.1002/admt.202201472

Surface modifications of COP-based microfluidic devices for improved immobilisation of hydrogel proteins: long-term 3D culture with contractile cell types and ischaemia model

Autoren: Sandra González-Lana, Teodora Randelovic, Jesús Ciriza, María López-Valdeolivas, Rosa Monge, Carlos Sánchez Somolinos, Ignacio Ochoa
Veröffentlicht in: Lab on a Chip, 2023, Seite(n) 2434-2446, ISSN 1473-0197
Herausgeber: Royal Society of Chemistry
DOI: 10.1039/d3lc00075c

Towards novel biomimetic in vitro models of the blood-brain barrier for drug permeability evaluation

Autoren: Mármol, Inés; Abizanda-Campo, Sara; Ayuso, José M.; Ochoa, Ignacio; Oliván, Sara
Veröffentlicht in: Bioengineering, Ausgabe 10, 2023, ISSN 2306-5354
Herausgeber: MDPI

In vitro biomimetic models for glioblastoma-a promising tool for drug response studies

Autoren: Tijana Stankovića, Teodora Ranđelović, Miodrag Dragoj, Sonja Stojković Burić, LuisFernández, Ignacio Ochoa, Victor M.Pérez-García, MilicaPešić
Veröffentlicht in: Drug Resistance Updates, 2021, ISSN 1368-7646
Herausgeber: Churchill Livingstone
DOI: 10.1016/j.drup.2021.100753

Reprogrammable 4D printed liquid crystal elastomer photoactuators by means of light-resersible perylene diimide radicals

Autoren: Lorena Montesino, Jesus I. Martinez, C. Sanchez Somolinos
Veröffentlicht in: Advanced functional materials, 2023, ISSN 1616-301X
Herausgeber: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202309019

Thermal Paper and Time Temperature Integrators Made From a Structural Colored Polymer Crosslinked With Hydrogen Bonded Cyclohexanoic Acid Derivatives

Autoren: Foelen, Yari; van der Heijden, Daniëlle A. C.; Verdurmen, Anne M. J.; Mulder, Dirk J.; Lub, Johan; Schenning, Albert P. H. J.
Veröffentlicht in: Advanced optical materials, Ausgabe 1, 2022, Seite(n) 2201462, ISSN 2195-1071
Herausgeber: Wiley-VCH GmbH
DOI: 10.1002/adom.202201462

Four-Dimensional Printed Liquid Crystalline Elastomer Actuators with Fast Photoinduced Mechanical Response toward Light-Driven Robotic Functions

Autoren: Lorena Ceamanos, Zehra Kahveci, María López-Valdeolivas, Danqing Liu, Dirk Jan Broer, Carlos Sánchez-Somolinos
Veröffentlicht in: ACS Applied Materials & Interfaces, Ausgabe 12/39, 2020, Seite(n) 44195-44204, ISSN 1944-8244
Herausgeber: American Chemical Society
DOI: 10.1021/acsami.0c13341

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