Multivalent interactions driving RNP dynamics in development and disease

Project Information

RNPdynamics

Grant agreement ID: 835300

DOI

10.3030/835300

Project closed

EC signature date 2 December 2019

Start date 1 January 2020

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 396 261,25

EU contribution

€ 2 396 261,25

Coordinated by

KEMIJSKI INSTITUT
Slovenia

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (4)

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Author(s): Brown AL, Wilkins OG, …, Secrier M, Lashley T, Ule J, Buratti E, Humphrey J, Ward ME, Fratta P
Published in: Nature, 2022, Page(s) Mar;603(7899):131-137, ISSN 1476-4687
Publisher: Springer
DOI: 10.1038/s41586-022-04436-3

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

Author(s): Simone R, Javad F, Emmett W, Wilkins OG, …, Warner TT, Plagnol V, Ule J, de Silva R.
Published in: Nature, 2021, ISSN 1476-4687
Publisher: Springer
DOI: 10.1038/s41586-021-03556-6

TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

Author(s): Martina Hallegger; Martina Hallegger; Anob M. Chakrabarti; Flora C.Y. Lee; Flora C.Y. Lee; Bo Lim Lee; Aram G. Amalietti; Aram G. Amalietti; Hana M. Odeh; Katie E. Copley; Jack D. Rubien; Bede Portz; Klara Kuret; Ina Huppertz; Frédérique Rau; Frédérique Rau; Rickie Patani; Rickie Patani; Nicolas L. Fawzi; James Shorter; Nicholas M. Luscombe; Nicholas M. Luscombe; Jernej Ule; Jernej Ule
Published in: Cell, 2021, Page(s) vol. 184, no. 18, pp. 4680-4696,e1-e22, ISSN 1097-4172
Publisher: Cell
DOI: 10.1016/j.cell.2021.07.018

Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP

Author(s): Klara Kuret; Aram Gustav Amalietti; D. Marc Jones; Charlotte Capitanchik; Jernej Ule
Published in: Genome biology, Issue vol. 23, no. 1, 2022, Page(s) 1-34, ISSN 1474-7596
Publisher: BioMed Central
DOI: 10.1186/s13059-022-02755-2