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Effective combinational treatment of chronic pain in individual patients, by an innovative quantitative systems pharmacology pain relief approach.

Project description

New way to fight chronic pain

Chronic pain is pain that lasts a long time, even after an injury heals. It affects more than 20 % of the population causing problems in everyday life. Chronic pain is treated with a combination of several analgesic drugs administered according to each physician’s decision based on their own best experiences. This is often not effective and it could even cause harmful effects. The EU-funded QSPainRelief project will develop a platform to improve treatment and relieve chronic pain with an effective combination of drugs thanks to a mechanism of quantitative systems pharmacology based on mathematical modelling (in silico modelling). It will allow physicians to identify and test effective, personally targeted therapy through the smart combination of drugs for each patient case.

Field of science

  • /medical and health sciences/basic medicine/pharmacology and pharmacy/pharmacokinetics
  • /medical and health sciences/basic medicine/pharmacology and pharmacy

Call for proposal

H2020-SC1-2019-Two-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITEIT LEIDEN
Address
Rapenburg 70
2311 EZ Leiden
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 404 207,50

Participants (9)

IN SILICO BIOSCIENCES, INC
United States
EU contribution
€ 1 095 875
Address
405 Waltham Street
02421 Lexington Ma
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
PD-VALUE BV
Netherlands
EU contribution
€ 298 375
Address
Molenaarserf 102
3991 KT Houten
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Concentris Research Management GmbH
Germany
EU contribution
€ 530 000
Address
Ludwigstr. 4
D-82256 Fürstenfeldbruck
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSIDAD AUTONOMA DE BARCELONA
Spain
EU contribution
€ 340 875
Address
Calle Campus Universitario Sn Cerdanyola V
08290 Cerdanyola Del Valles
Activity type
Higher or Secondary Education Establishments
UNIVERSIDAD POMPEU FABRA
Spain
EU contribution
€ 585 875
Address
Placa De La Merce, 10-12
08002 Barcelona
Activity type
Higher or Secondary Education Establishments
ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
Italy
EU contribution
€ 390 875
Address
Via Zamboni 33
40126 Bologna
Activity type
Higher or Secondary Education Establishments
UNIVERSITE CATHOLIQUE DE LOUVAIN
Belgium
EU contribution
€ 848 320
Address
Place De L Universite 1
1348 Louvain La Neuve
Activity type
Higher or Secondary Education Establishments
STICHTING CENTRE FOR HUMAN DRUG RESEARCH
Netherlands
EU contribution
€ 677 636,25
Address
Zernikedreef 10
2333 CL Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
CLINIQUES UNIVERSITAIRES SAINT-LUC
Belgium
EU contribution
€ 67 500
Address
Avenue Hippocrate 10
1200 Bruxelles
Activity type
Research Organisations