Descrizione del progetto
Diagnosi e intervento precoci della paralisi celebrale
La paralisi cerebrale (PC) è un gruppo di disturbi del movimento e della postura che provocano una limitazione dell’attività dovuta a disfunzioni che si sono verificate nel cervello fetale o infantile. È la disabilità fisica più comune e si verifica in 2,1 nascite su 1 000. Sfortunatamente, viene spesso diagnosticata non prima dei due anni. Questo ritardo può causare drammatiche conseguenze sul lungo termine per bambini e genitori. Pertanto, una diagnosi (Early Detection, ED) e intervento (Early Intervention, EI) precoci sono particolarmente importanti. Il progetto BornToGetThere, finanziato dall’UE, mira a sviluppare le Linee guida per la pratica clinica internazionale in Europa, PRMB e popolazioni remote. Esso fornirà prove, conoscenze e procedure ottimizzate per l’identificazione precoce dei casi ad alto rischio e offrirà servizi clinici mirati ed efficaci per prevenire complicazioni di salute secondarie. Il progetto BornToGetThere contribuirà ad adattare i programmi EI ai diversi sistemi e ambienti di assistenza sociale.
Obiettivo
Despite advances in the medical management of high-risk pregnancies and deliveries, cerebral palsy (CP) remains the most common physical disability in childhood in high and low-to-middle income (LMIC). In addition, caregivers of children with CP are at higher risk of psychiatric issues, further increasing health and socio-economic burden to the families. In spite of the scientific advancements in early detection and intervention (EI) in CP, there is a lack of implementation into clinical service delivery. The overarching aim of the BORNTOGETTHERE program is to exploit current evidence on early detection and efficacy of EI for infants at high risk of CP by implementing the International Clinical Practice Guideline in Europe (Italy, Denmark, Netherlands), LMIC (Georgia, Sri Lanka) and hard to reach populations (Remote Queensland and Western Australia). It will provide a multifaceted knowledge translation approach focused on i) optimizing context-specific health programs for early detection of CP, thus reducing age at diagnosis and age at referral to EI; ii) optimizing early functional characterization of infants with CP, thereby fostering personalized EI and preventing secondary complications (i.e. hip dislocation) and iii) testing the implementation of integrated EI programs adapted to country-specific welfare systems. The protocol of service delivery will result from the adaptation of early detection and EI programs based on the proven, effective intervention strategies, and those that are included into ongoing research based on effectiveness shown with preliminary data. This framework will be validated in real life varying world conditions through a large implementation program and a multicentre parallel controlled trial. The main beneficiaries will include a wide range of stakeholders: not only concerned families and communities but also policy makers, public authorities, the media, and citizen groups to ensure the translation of evidence into routine practice.
Campo scientifico
Parole chiave
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-SC1-2019-Two-Stage-RTD
Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
56126 Pisa
Italia