Risultati finali
Description of dominant MPSG in high risk areas (that tend to elect not to participate but which are at high risk), and of MPSG for optimisation in those who tend to participate (M6)
Biomarkers: Validation circulating miRNAValidation of two different computational models of circulating miRNAs to maximize sensitivity for risk prediction and specificity for differential diagnosis
Project Management: informed consent form- The informed consent procedures that will be implemented for the participation of humans will be explained into detail. - providing templates of the informed consent form (per country)
Biomarkers: composite risk predicting panelCombination of miRNAs, inflammatory proteins and cardio-pulmonary damage in a composite risk predicting panel.
recruitment: development tailored recruitmentIdentification of the preferred per country and most effective channels of communication and development of the tailored intervention, with different MPSG profiles, at high risk of developing lung cancer, including qualitative data on the participants’ view of the methods
Protocol: study protocol 4-IN-THE-LUNG-RUNDesign of the study protocol
Data protection: securityA description of the security measures that will be implemented to prevent unauthorised access to personal data or the equipment used for processing
Protocol: Nodule Management Strategydesign of the lung cancer nodule management protocol
Approval: study protocol - registrationi Final version of study protocol as submitted to regulatorsethics committees ii Registration number of clinical study in a WHOor ICMJE approved registry with the possibility to post resultsiii Approvals ethics committees and national competent authority if applicable required for invitationenrolment of first subject in at least one clinical centre
Data protection: privacy - anonymised/ pseudomysed dataexplain why the research data will not be anonymised/ pseudonymised
Pubblicazioni
Autori:
Kevin Haaf, Carlijn M. Aalst, Harry J. Koning, Rudolf Kaaks, Martin C. Tammemägi
Pubblicato in:
International Journal of Cancer, Numero 149/2, 2021, Pagina/e 250-263, ISSN 0020-7136
Editore:
John Wiley & Sons Inc.
DOI:
10.1002/ijc.33578
Autori:
Carlijn M. van der Aalst, Kevin ten Haaf, Harry J. de Koning
Pubblicato in:
Translational Lung Cancer Research, Numero 10/2, 2021, Pagina/e 1050-1063, ISSN 2218-6751
Editore:
AME Publishing Company
DOI:
10.21037/tlcr-20-985
Autori:
M. Vonder, C. van der Aalst, J. Hubert, D. Moldovanu, A. Schmitz, J.W.C. Gratama, M. Silva, H. de Koning, M. Oudkerk
Pubblicato in:
Journal of Thoracic Oncology, Numero Volume 18, Numero 11, Supplement, 2023, 2023, Pagina/e Pages S218-S219, ISSN 1556-0864
Editore:
Lippincott Williams & Wilkins Ltd.
DOI:
10.1016/j.jtho.2023.09.355
Autori:
Koen de Nijs, Kevin ten Haaf, Carlijn van der Aalst, and Harry J. de Koning
Pubblicato in:
eClinical Medicine, Numero 2024; 102570, 2024, Pagina/e 102570, ISSN 2589-5370
Editore:
Elsevier BV
DOI:
10.1016/j.eclinm.2024.102570
Autori:
M. Vonder, C. van der Aalst, D. Moldovanu, J. Hubert, A. Schmitz, J. Gratama, M. Silva, H. de Koning, M. Oudkerk
Pubblicato in:
Journal of Cardiovascular Computed Tomography, Numero Volume 17, Numero 4, Supplement, 2023, Pagina/e S46, ISSN 1934-5925
Editore:
Elsevier BV
DOI:
10.1016/j.jcct.2023.05.116
Autori:
Dana Moldovanu, Harry J. de Koning, Carlijn M. van der Aalst
Pubblicato in:
Translational Lung Cancer Research, Numero 10/2, 2021, Pagina/e 1099-1109, ISSN 2218-6751
Editore:
AME Publishing Company
DOI:
10.21037/tlcr-20-899
Autori:
C. van der Aalst, M. Vonder, J. Hubert, D. Moldovanu, A. Schmitz, S. Delorme, R. Kaaks, K. ten Haaf , M. Oudkerk, H. de Koning
Pubblicato in:
Journal of Thoracic Oncology, Numero Volume 18, Numero 11, Supplement, November 2023, 2023, Pagina/e Page S217, ISSN 1556-1380
Editore:
Elsevier
DOI:
10.1016/j.jtho.2023.09.352
Autori:
M. Vonder, C. van der Aalst, J. Hubert, D. Moldovanu, A. Schmitz, S. Delorme, J.W. Gratama, M. Silva, H. de Koning, M. Oudkerk
Pubblicato in:
Journal of Thoracic Oncology, Numero Volume 18, Numero 11, Supplement, November 2023, 2023, Pagina/e Page S172, ISSN 1556-1380
Editore:
Elsevier
DOI:
10.1016/j.jtho.2023.09.256
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