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Interactive web-based tool for the design of multi-RNA binding protein binding site cassettes

Project description

Novel multi-RNA binding tool to boost synthetic biology research

In a lock-and-key fashion, RNA-binding proteins bind RNA at one or more RNA-binding domains to modulate gene expression by altering RNA processing and translation. Hundreds of 'keys' have been discovered over the years and recent studies have revealed even more. Characterising their interaction and subsequent biological implications is a huge area of research expected to reveal previously unidentified structures and functions for numerous applications. CARBP is supporting that effort with software to quickly and intelligently design RNA-binding domains and create synthetic DNA libraries. The software will be part of a suite of web-based tools that could tremendously increase the rate of discovery, depth of understanding and ultimate utility of novel molecules involved in gene expression.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-03

Coordinator

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Net EU contribution
€ 68 750,00
Address
Senate Building Technion City
32000 Haifa
Israel

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (1)

REICHMAN UNIVERSITY
Israel
Net EU contribution
€ 31 250,00
Address
8 Hauniversita St
4610101 Herzliya

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Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00