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Therapeutic hijacking of E3 Ligases

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Rational discovery of molecular glue degraders via scalable chemical profiling

Author(s): Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H. Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C. Müller, Johannes Zuber, Matthias Geyer, Nicolas H. Thomä, Stefan Kubicek, Georg E. Winter
Published in: Nature Chemical Biology, 16/11, 2020, Page(s) 1199-1207, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/s41589-020-0594-x