Quantifying minute forces: How mechanoregulation determines the behavior of pathogenic bacteria

Project Information

BacForce

Grant agreement ID: 852585

DOI 10.3030/852585

EC signature date 27 January 2020

Start date 1 August 2020

End date 31 July 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 498 864,00

EU contribution € 1 498 864,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

Publications

Peer reviewed articles (6)

Type-IV pili tune an adhesion-migration trade-off during surface colonization of Pseudomonas aeruginosa

Author(s): A.N. Simsek, M.D. Koch, J.E. Sanfilippo, Z. Gitai, G. Gompper, B. Sabass
Published in: bioRxiv Preprint, 2023, ISSN 2692-8205
Publisher: Cold Spring Harbour Laboratory
DOI: 10.1101/2023.05.09.538458

Sparse inference and active learning of stochastic differential equations from data

Author(s): Y. Huang, Y. Mabrouk, Gompper, Sabass
Published in: Sci Rep, Issue 12, 21691, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-25638-9

Shear force enhances adhesion of Pseudomonas aeruginosa by counteracting pilus-driven surface departure

Author(s): J.-J. S Palalay, A.N. Simsek, B. Sabass, J.E. Sanfilippo
Published in: Proc. Nat. Acad. Sci., 2023, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1101/2023.05.08.539440

Non-equilibrium dynamics of bacterial colonies -- growth, active fluctuations, segregation, adhesion, and invasion

Author(s): Kai Zhou, Marc Hennes, Berenike Maier, Gerhard Gompper, Benedikt Sabass
Published in: Communications Physics, Issue volume 5, Article number: 251, 2022, ISSN 2399-3650
Publisher: Springer Nature
DOI: 10.1038/s42005-022-01018-7

EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

Author(s): Jasmin I.Maier, Manuel Rogg, Martin Helmstädter, Alena Sammarco, Oliver Schilling, Benedikt Sabass, Jeffrey H. Miner, Jörn Dengjel, Gerd Walz, Martin Werner, Tobias B.Huber, Christoph Schell
Published in: Cell Reports, Issue Volume 34, Issue 12, 23 March 2021, 2021, Page(s) 108883, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.108883

A generic self-stabilization mechanism for biomolecular adhesions under load

Author(s): Braeutigam, Andrea; Simsek, Ahmet Nihat; Gompper, Gerhard; Sabass, Benedikt
Published in: Nature Communications, Issue volume 13, Article number: 2197, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-29823-2

Book chapters (2)

Quantitative Analysis of Myofibroblast Contraction by Traction Force Microscopy

Author(s): Shuying Yang, Fernando R. Valencia, Benedikt Sabass, Sergey V. Plotnikov
Published in: Methods in Molecular Biology book series (MIMB,volume 2299), 2021
Publisher: Springer Nature
DOI: 10.1007/978-1-0716-1382-5_14

Computational Physics of Active Matter

Author(s): Sabass, Benedikt and Winkler, Roland G and Auth, Thorsten and Elgeti, Jens and Fedosov, Dmitry A and Ripoll, Marisol and Vliegenthart, Gerard A and Gompper, Gerhard
Published in: Out-of-equilibrium Soft Matter, 2023, Page(s) 354--390
Publisher: The Royal Society of Chemistry

Thesis and dissertations (3)

Micromechanics of bacterial surface-migration

Author(s): Ahmet Simsek
Published in: 2021
Publisher: Kölner Publikationsserver

Advanced data analysis for traction force microscopy and data-driven discovery of physical equations

Author(s): Yunfei Huang
Published in: 2021
Publisher: Kölner Publikationsserver

Response of stochastic adhesion clusters to pulling and shearing forces.

Author(s): Andrea Bräutigam
Published in: 2021
Publisher: Kölner Publikationsserver

Other (1)

Not just a number: what cells feel depends on how they grab it

Author(s): B. Sabass
Published in: Biophys. J., Issue Volume 121, ISSUE 9, 2022, Page(s) 1581-1582
Publisher: Cell Press
DOI: 10.1016/j.bpj.2022.04.004