Quantifying minute forces: How mechanoregulation determines the behavior of pathogenic bacteria

Información del proyecto

BacForce

Identificador del acuerdo de subvención: 852585

DOI

10.3030/852585

Fecha de la firma de la CE 27 Enero 2020

Fecha de inicio 1 Agosto 2020

Fecha de finalización 31 Julio 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 498 864,00

Aportación de la UE

€ 1 498 864,00

Coordinado por

TECHNISCHE UNIVERSITAT DORTMUND
Germany

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (11)

Type-IV pili tune an adhesion-migration trade-off during surface colonization of Pseudomonas aeruginosa

Autores: A.N. Simsek, M.D. Koch, J.E. Sanfilippo, Z. Gitai, G. Gompper, B. Sabass
Publicado en: bioRxiv Preprint, 2023, ISSN 2692-8205
Editor: Cold Spring Harbour Laboratory
DOI: 10.1101/2023.05.09.538458

Sparse inference and active learning of stochastic differential equations from data

Autores: Y. Huang, Y. Mabrouk, Gompper, Sabass
Publicado en: Sci Rep, Edición 12, 21691, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-25638-9

Sensory adaptation in a continuum model of bacterial chemotaxis—working range, cost-accuracy relation, and coupled systems

Autores: Vansh Kharbanda, Benedikt Sabass
Publicado en: New Journal of Physics, Edición 26, 2024, Página(s) 023045, ISSN 1367-2630
Editor: Institute of Physics Publishing
DOI: 10.1088/1367-2630/ad26ba

Bacteria Tune a Trade-off between Adhesion and Migration to Colonize Surfaces under Flow

Autores: Ahmet Nihat Simsek, Matthias D. Koch, Joseph E. Sanfilippo, Zemer Gitai, Gerhard Gompper, Benedikt Sabass
Publicado en: PRX Life, Edición 2, 2024, ISSN 2835-8279
Editor: American Physical Society (APS)
DOI: 10.1103/prxlife.2.023003

Multi-Modal Analysis of Satellite Cells Reveals Early Impairments at Pre-Contractile Stages of Myogenesis in Duchenne Muscular Dystrophy

Autores: Sophie Franzmeier, Shounak Chakraborty, Armina Mortazavi, Jan B. Stöckl, Jianfei Jiang, Nicole Pfarr, Benedikt Sabass, Thomas Fröhlich, Clara Kaufhold, Michael Stirm, Eckhard Wolf, Jürgen Schlegel, Kaspar Matiasek
Publicado en: Cells, Edición 14, 2025, Página(s) 892, ISSN 2073-4409
Editor: MDPI AG
DOI: 10.3390/cells14120892

Shear force enhances adhesion of Pseudomonas aeruginosa by counteracting pilus-driven surface departure

Autores: J.-J. S Palalay, A.N. Simsek, B. Sabass, J.E. Sanfilippo
Publicado en: Proc. Nat. Acad. Sci., 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1101/2023.05.08.539440

Non-equilibrium dynamics of bacterial colonies -- growth, active fluctuations, segregation, adhesion, and invasion

Autores: Kai Zhou, Marc Hennes, Berenike Maier, Gerhard Gompper, Benedikt Sabass
Publicado en: Communications Physics, Edición volume 5, Article number: 251, 2022, ISSN 2399-3650
Editor: Springer Nature
DOI: 10.1038/s42005-022-01018-7

Clutch model for focal adhesions predicts reduced self-stabilization under oblique pulling

Autores: Andrea Braeutigam, Anton F Burnet, Gerhard Gompper, Benedikt Sabass
Publicado en: Journal of Physics: Condensed Matter, Edición 36, 2024, Página(s) 295101, ISSN 0953-8984
Editor: Institute of Physics Publishing
DOI: 10.1088/1361-648x/ad3ac1

Shear force enhances adhesion of <i>Pseudomonas aeruginosa</i> by counteracting pilus-driven surface departure

Autores: Jessica-Jae S. Palalay, Ahmet N. Simsek, Jessie L. Reed, Matthias D. Koch, Benedikt Sabass, Joseph E. Sanfilippo
Publicado en: Proceedings of the National Academy of Sciences, Edición 120, 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2307718120

EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission

Autores: Jasmin I.Maier, Manuel Rogg, Martin Helmstädter, Alena Sammarco, Oliver Schilling, Benedikt Sabass, Jeffrey H. Miner, Jörn Dengjel, Gerd Walz, Martin Werner, Tobias B.Huber, Christoph Schell
Publicado en: Cell Reports, Edición Volume 34, Edición 12, 23 March 2021, 2021, Página(s) 108883, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2021.108883

A generic self-stabilization mechanism for biomolecular adhesions under load

Autores: Braeutigam, Andrea; Simsek, Ahmet Nihat; Gompper, Gerhard; Sabass, Benedikt
Publicado en: Nature Communications, Edición volume 13, Article number: 2197, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-29823-2

Book chapters (2)

Quantitative Analysis of Myofibroblast Contraction by Traction Force Microscopy

Autores: Shuying Yang, Fernando R. Valencia, Benedikt Sabass, Sergey V. Plotnikov
Publicado en: Methods in Molecular Biology book series (MIMB,volume 2299), 2021
Editor: Springer Nature
DOI: 10.1007/978-1-0716-1382-5_14

Computational Physics of Active Matter

Autores: Sabass, Benedikt and Winkler, Roland G and Auth, Thorsten and Elgeti, Jens and Fedosov, Dmitry A and Ripoll, Marisol and Vliegenthart, Gerard A and Gompper, Gerhard
Publicado en: Out-of-equilibrium Soft Matter, 2023, Página(s) 354--390
Editor: The Royal Society of Chemistry

Thesis and dissertations (3)

Micromechanics of bacterial surface-migration

Autores: Ahmet Simsek
Publicado en: 2021
Editor: Kölner Publikationsserver

Advanced data analysis for traction force microscopy and data-driven discovery of physical equations

Autores: Yunfei Huang
Publicado en: 2021
Editor: Kölner Publikationsserver

Response of stochastic adhesion clusters to pulling and shearing forces.

Autores: Andrea Bräutigam
Publicado en: 2021
Editor: Kölner Publikationsserver

Other (4)

Hijacked Immune Cells Traverse Microenvironmental Barriers by Positioning and Pushing their Intracellular Parasite Cargo

Autores: Mauricio J.A. Ruiz-Fernandez, Jianfei Jiang, Armina Mortazavi, Bingzhi Wang, Artur Kuznetcov, Jack Merrin, Markus Meissner, Javier Periz, Benedikt Sabass, Jörg Renkawitz
Publicado en: 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.05.03.592378

Not just a number: what cells feel depends on how they grab it

Autores: B. Sabass
Publicado en: Biophys. J., Edición Volume 121, ISSUE 9, 2022, Página(s) 1581-1582
Editor: Cell Press
DOI: 10.1016/j.bpj.2022.04.004

A reliable<i>in vitro</i>rumen culture system and workflow for screening anti-methanogenic compounds

Autores: Philip P. Laric, Armina Mortazavi, Ewa Węgrzyn, Kathrin Simon, Pauline S. Rittel, Florian M. Trefz, Benedikt Sabass
Publicado en: 2025
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.03.03.641173

Traction Force Microscopy with DNA FluoroCubes

Autores: Armina Mortazavi, Jianfei Jiang, Philip Laric, Dominic A. Helmerich, Rick Seifert, Markus Sauer, Benedikt Sabass
Publicado en: 2024
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.04.12.589182