PHAGOSCOPY: Dissecting cell-autonomous immunity with ex vivo electron cryo-microscopy

Project Information

PHAGOSCOPY

Grant agreement ID: 852880

DOI

10.3030/852880

EC signature date 5 November 2019

Start date 1 February 2020

End date 31 January 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 438 510,00

EU contribution

€ 1 438 510,00

Coordinated by

TECHNISCHE UNIVERSITEIT DELFT
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

A data management plan on how data generated by the project are stored and made available

Publications

Peer reviewed articles (6)

Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes

Author(s): Stefan T. Huber; Edin Sarajlic; Roeland Huijink; Felix Weis; Wiel H. Evers; Arjen J. Jakobi
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications

Robust Local Thickness Estimation of Sub‐Micrometer Specimen by 4D‐STEM

Author(s): Radim Skoupý, Daan B. Boltje, Miroslav Slouf, Kateřina Mrázová, Tomáš Láznička, Clémence M. Taisne, Vladislav Krzyžánek, Jacob P. Hoogenboom, Arjen J. Jakobi
Published in: Small Methods, Issue 7, 2024, ISSN 2366-9608
Publisher: Wiley-VCH GmbH
DOI: 10.1002/smtd.202300258

Thickness- and quality-controlled fabrication of fluorescence-targeted frozen-hydrated lamellae

Author(s): Daan B. Boltje, Radim Skoupý, Clémence Taisne, Wiel H. Evers, Arjen J. Jakobi, Jacob P. Hoogenboom
Published in: Cell Reports Methods, Issue 5, 2025, Page(s) 101004, ISSN 2667-2375
Publisher: Cell Press
DOI: 10.1016/j.crmeth.2025.101004

Structural basis of antimicrobial membrane coat assembly by human GBP1

Author(s): Tanja Kuhm, Clémence Taisne, Cecilia de Agrela Pinto, Luca Gross, Evdokia A. Giannopoulou, Stefan T. Huber, Els Pardon, Jan Steyaert, Sander J. Tans, Arjen J. Jakobi
Published in: Nature Structural & Molecular Biology, Issue 32, 2025, Page(s) 172-184, ISSN 1545-9993
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-024-01400-9

A cryogenic, coincident fluorescence, electron, and ion beam microscope

Author(s): Daan B Boltje, Jacob P Hoogenboom, Arjen J Jakobi, Grant J Jensen, Caspar TH Jonker, Max J Kaag, Abraham J Koster, Mart GF Last, Cecilia de Agrela Pinto, Jürgen M Plitzko, Stefan Raunser, Sebastian Tacke, Zhexin Wang, Ernest B van der Wee, Roger Wepf, Sander den Hoedt
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.82891

Electron scattering properties of biological macromolecules and their use for cryo-EM map sharpening

Author(s): Arjen Jakobi; Alok Bharadwaj
Published in: Faraday Discussions, 2022, Page(s) 168-183, ISSN 1359-6640
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2fd00078d