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Dna Damage REsponse: Actionabilities, Maps and Mechanisms


PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants

Author(s): Siegner SM, Karasu ME, Schröder MS, Kontarakis Z, Corn JE
Published in: BMC Bioinformatics, Issue Mar 2;22(1):101, 2021, ISSN 1471-2105
Publisher: BioMed Central
DOI: 10.1186/s12859-021-04034-6

Recursive Editing improves homology-directed repair through retargeting of undesired outcomes

Author(s): Möller, Lukas; Aird, Eric Jackson; id_orcid0000-0002-4873-042X; Schröder, Markus; id_orcid0000-0001-5942-1254; Kobel, Lena; id_orcid0000-0001-7949-141X; Kissling, Lucas; van de Venn, Lilly; Corn, Jacob; id_orcid0000-0002-7798-5309
Published in: Nature Communications, 13 (1), Issue 3, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-31944-7

Tissue specificity of DNA repair: the CRISPR compass

Author(s): Joana Ferreira da Silva, Mathilde Meyenberg, Joanna I. Loizou
Published in: Trends in Genetics, Issue 37/11, 2021, Page(s) 958-962, ISSN 0168-9525
Publisher: Elsevier BV
DOI: 10.1016/j.tig.2021.07.010

Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair

Author(s): J. Ferreira da Silva; G. P. Oliveira; E. A. Arasa-Verge; C. Kagiou; A. Moretton; G. Timelthaler; J. Jiricny; J. I. Loizou
Published in: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022), Issue 2, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.3929/ethz-b-000533332

Clinical prospects of WRN inhibition as a treatment for MSI tumours.

Author(s): Morales-Juarez, D.A., Jackson, S.P.
Published in: npj Precision Oncology, Issue 6, 2022, Page(s) 85, ISSN 2397-768X
Publisher: Springer Nature
DOI: 10.1038/s41698-022-00319-y

Nurturing a revolution in DNA repair and cancer therapy through CRISPR–Cas screens

Author(s): Samah W. Awwad, Almudena Serrano-Benitez, John C. Thomas, Vipul Gupta, Stephen P. Jackson
Published in: Nature Reviews Molecular Cell Biology, Issue Published: 13 February 2023, 2023, ISSN 1471-0072
Publisher: Nature Publishing Group
DOI: 10.1038/s41580-022-00571-x

Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing

Author(s): Mathilde Meyenberg, Joana Ferreira da Silva, Joanna I. Loizou
Published in: Frontiers in Genetics, Issue 12, 2021, Page(s) 728520, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2021.728520

Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy

Author(s): Anna Schrempf, Jana Slyskova, Joanna I. Loizou
Published in: Trends in Cancer, Issue VOLUME 7, ISSUE 2, FEBRUARY 01, 2021, 2020, Page(s) 98-111, ISSN 2405-8033
Publisher: ELSEVIER BV
DOI: 10.1016/j.trecan.2020.09.007

Decomposing the mutational landscape of cancer genomes with RepairSig

Author(s): SaraBernardo, Mathilde Meyenberg, Joanna I.Loizou
Published in: Cell Systems, Issue Volume 12, Issue 10, 20 October 2021, 2021, Page(s) 953-955, ISSN 2405-4720
Publisher: Cell Press
DOI: 10.1016/j.cels.2021.09.009

Prime Editing Efficiency and Fidelity are Enhanced in the Absence of Mismatch Repair

Author(s): J Ferreira da Silva, GP Oliveira, EA Arasa-Verge, A Moretton, G Timelthaler, J Jiricny, JI Loizou
Published in: BioRxiv, Issue Posted September 30, 2021., 2021, Page(s) 1-17, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratories
DOI: 10.1101/2021.09.30.462548

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