Networking for excellence in functional pharmacology to study the role of fatty acid metabolism in neurological disorders

Leistungen

1st dissemination and communication report
Minutes from the 3rd year Executive Board meeting

Minutes from the FAT4BRAIN 3rd year Executive Board meeting

Report on organized events and trainings M1-12
Report on visits and participation in capacity-building events

Report on UU and EKUT researcher visits and participation in capacitybuilding events

Minutes from the 2nd year Executive Board meeting

Minutes from the FAT4BRAIN 2nd year Executive Board meeting

Strategy and plan for ESR involvement

Strategy and plan for ESR involvement in FAT4BRAIN activities and establishment of mentoring platform

Report on organized events and trainings M25-40

Report on organized events and trainings M2540

Report on LIOS researcher visits and participation in capacity-building events

Report on LIOS researcher visits and participation in capacitybuilding events

Minutes from the kick-off meeting
Communication channels and visual identity

Created FAT4BRAIN communication channels and visual identity

Communication Strategy and Plan of Exploitation and Dissemination of Results
Report on organized events and trainings M13-24

Report on organized events and trainings M1324

Report on researcher visits and participation in capacity-building events

Report on OROBOROS researcher visits and participation in capacitybuilding events

Minutes from the 1st year Executive Board meeting

Minutes from the FAT4BRAIN 1st year Executive Board meeting

2nd dissemination and communication report

Data management plan

Development of data management plan

Veröffentlichungen

Effects of Transient Administration of the NMDA Receptor Antagonist MK-801 in Drosophila melanogaster Activity, Sleep, and Negative Geotaxis

Autoren: Moulin TC, Stojanovic T, Rajesh RP, Pareek T, Donzelli L, Williams MJ, Schiöth HB
Veröffentlicht in: Biomedicines, 2023, ISSN 2227-9059
Herausgeber: MDPI
DOI: 10.3390/biomedicines11010192

Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage

Autoren: Liepinsh E, Kuka J, Vilks K, Svalbe B, Stelfa G, Vilskersts R, Sevostjanovs E, Goldins NR, Groma V, Grinberga S, Plaas M, Makrecka-Kuka M, Dambrova M
Veröffentlicht in: Free Radical Biology and Medicine, 2021, ISSN 1873-4596
Herausgeber: Elsevier
DOI: 10.1016/j.freeradbiomed.2021.10.035

Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload

Autoren: Marina Makrecka-Kuka, Stanislava Korzh, Melita Videja, Karlis Vilks, Helena Cirule, Janis Kuka, Maija Dambrova, Edgars Liepinsh
Veröffentlicht in: Cardiovascular Drugs and Therapy, Ausgabe 34/6, 2020, Seite(n) 791-797, ISSN 0920-3206
Herausgeber: Kluwer Academic Publishers
DOI: 10.1007/s10557-020-06989-9

Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical dimensions

Autoren: Zümrüt Duygu Sen, Lena Vera Danyeli, Marie Woelfer, Femke Lamers, Gerd Wagner, Thomas Sobanski, Martin Walter
Veröffentlicht in: Brain, Behavior, and Immunity, Ausgabe 93, 2021, Seite(n) 335-352, ISSN 0889-1591
Herausgeber: Academic Press
DOI: 10.1016/j.bbi.2020.12.020

Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats

Autoren: Kuka J, Makrecka-Kuka M, Vilks K, Korzh S, Cirule H, Sevostjanovs E, Grinberga S, Dambrova M, Liepinsh E
Veröffentlicht in: Oxidative Medicine and Cellular Longevity, 2021, ISSN 1942-0994
Herausgeber: Hindawi
DOI: 10.1155/2021/7493190

Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity

Autoren: Zelencova-Gopejenko D, Videja M, Grandane A, Pudnika-Okinčica L, Sipola A, Vilks K, Dambrova M, Jaudzems K, Liepinsh E
Veröffentlicht in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065528

Acylcarnitines: Nomenclature, biomarkers, therapeutic potential, drug targets and clinical trials

Autoren: Dambrova M, Makrecka-Kuka M, Kuka J, Vilskersts R, Nordberg D, Attwood M, Smesny S, Duygu Sen Z, Chi Guo A, Oler E, Tian S, Wishart D, Liepinsh E, Schiöth H
Veröffentlicht in: Pharmacological Reviews, 2022, ISSN 1521-0081
Herausgeber: ASPET
DOI: 10.1124/pharmrev.121.000408

Reduced GFAP Expression in Bergmann Glial Cells in the Cerebellum of Sigma-1 Receptor Knockout Mice Determines the Neurobehavioral Outcomes after Traumatic Brain Injury

Autoren: Stelfa G, Vavers E, Svalbe B, Serzants R, Miteniece A, Lauberte L, Grinberga S, Gukalova B, Dambrova M, Zvejniece L
Veröffentlicht in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222111611

Multidrug Resistance Like Protein 1 Activity in Malpighian Tubules Regulates Lipid Homeostasis in Drosophila

Autoren: Liu W, Cao H, Kimari M, Maronitis G, Williams MJ, Schiöth HB
Veröffentlicht in: Membranes (Basel), 2021, ISSN 2077-0375
Herausgeber: Molecular Diversity Preservation International
DOI: 10.3390/membranes11060432

Transient Administration of Dopaminergic Precursor Causes Inheritable Overfeeding Behavior in Young Drosophila melanogaster Adults

Autoren: Moulin TC, Ferro F, Berkins S, Hoyer A, Williams MJ, Schiöth HB
Veröffentlicht in: Brain Sciences, 2020, ISSN 2076-3425
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/brainsci10080487

Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion

Autoren: Liepinsh E, Kuka J, Zvejniece L, Vilskersts R, Dambrova M
Veröffentlicht in: Journal of visualized experiments, 2022, ISSN 1940-087X
Herausgeber: MYJoVE Corporation
DOI: 10.3791/62942

Excitability, synaptic balance, and addiction: The homeostatic dynamics of ionotropic glutamatergic receptors in VTA after cocaine exposure

Autoren: Thiago C. Moulin, Helgi B. Schiöth
Veröffentlicht in: Behavioral and Brain Functions, Ausgabe 16/1, 2020, ISSN 1744-9081
Herausgeber: BioMed Central
DOI: 10.1186/s12993-020-00168-4

Evidence for Prepulse Inhibition of Visually Evoked Motor Response in Drosophila melanogaster

Autoren: Schiöth HB, Donzelli L, Williams MJ, Moulin TC
Veröffentlicht in: Biology, 2023, ISSN 2079-7737
Herausgeber: MDPI
DOI: 10.3390/biology12040635

Sigma-1 receptor and seizures.

Autoren: Vavers E, Zvejniece L, Dambrova M
Veröffentlicht in: Pharmacological Research, 2023, ISSN 2667-1425
Herausgeber: Elsevier
DOI: 10.1016/j.phrs.2023.106771

Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria

Autoren: Marina Makrecka-Kuka, Kristine Volska, Unigunde Antone, Reinis Vilskersts, Solveiga Grinberga, Dace Bandere, Edgars Liepinsh, Maija Dambrova
Veröffentlicht in: Toxicology Letters, Ausgabe 267, 2017, Seite(n) 32-38, ISSN 0378-4274
Herausgeber: Elsevier BV
DOI: 10.1016/j.toxlet.2016.12.017

Plasma acylcarnitine concentrations reflect the acylcarnitine profile in cardiac tissues

Autoren: Marina Makrecka-Kuka, Eduards Sevostjanovs, Karlis Vilks, Kristine Volska, Unigunde Antone, Janis Kuka, Elina Makarova, Osvalds Pugovics, Maija Dambrova, Edgars Liepinsh
Veröffentlicht in: Scientific Reports, Ausgabe 7/1, 2017, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-017-17797-x

The activity of selective sigma-1 receptor ligands in seizure models in vivo

Autoren: Edijs Vavers, Baiba Svalbe, Lasma Lauberte, Ilmars Stonans, Ilga Misane, Maija Dambrova, Liga Zvejniece
Veröffentlicht in: Behavioural Brain Research, Ausgabe 328, 2017, Seite(n) 13-18, ISSN 0166-4328
Herausgeber: Elsevier BV
DOI: 10.1016/j.bbr.2017.04.008

Effects of the N-methyl-d-aspartate receptor antagonist, MK-801, on spatial memory and influence of the route of administration

Autoren: Baiba Svalbe, Gundega Stelfa, Edijs Vavers, Baiba Zvejniece, Solveiga Grinberga, Eduards Sevostjanovs, Osvalds Pugovics, Maija Dambrova, Liga Zvejniece
Veröffentlicht in: Behavioural Brain Research, Ausgabe 372, 2019, Seite(n) 112067, ISSN 0166-4328
Herausgeber: Elsevier BV
DOI: 10.1016/j.bbr.2019.112067

Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB

Autoren: Janis Kuka, Marina Makrecka-Kuka, Helena Cirule, Solveiga Grinberga, Eduards Sevostjanovs, Maija Dambrova, Edgars Liepinsh
Veröffentlicht in: Basic & Clinical Pharmacology & Toxicology, Ausgabe 121/2, 2017, Seite(n) 106-112, ISSN 1742-7835
Herausgeber: Nordic Pharmacological Society
DOI: 10.1111/bcpt.12775

Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets

Autoren: Dambrova M, Cecatto C, Vilskersts R, Liepinsh E
Veröffentlicht in: Bioenergetics Communications, 2022, ISSN 2791-4690
Herausgeber: BEC
DOI: 10.26124/bec:2022-0015

Rodent and fly models in behavioral neuroscience: An evaluation of methodological advances, comparative research, and future perspectives

Autoren: Moulin TC, Covill LE, Itskov PM, Williams MJ, Schiöth HB
Veröffentlicht in: Neuroscience & Biobehavioral Reviews, 2021, ISSN 0149-7634
Herausgeber: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2020.11.014

Neurological manifestations of COVID-19: A comprehensive literature review and discussion of mechanisms

Autoren: Johansson A, Mohamed MS, Moulin TC, Schiöth HB
Veröffentlicht in: Journal of Neuroimmunology, 2021, ISSN 1872-8421
Herausgeber: Elsevier
DOI: 10.1016/j.jneuroim.2021.577658

The Drosophila melanogaster Levodopa-Induced Depression Model Exhibits Negative Geotaxis Deficits and Differential Gene Expression in Males and Females

Autoren: Moulin TC, Ferro F, Hoyer A, Cheung P, Williams MJ, Schiöth HB
Veröffentlicht in: Frontiers in Neuroscience, 2021, ISSN 1662-453X
Herausgeber: Frontiers
DOI: 10.3389/fnins.2021.653470

Acylcarnitines in health and disease: biomarkers and drug targets

Autoren: Dambrova M, Liepinsh E
Veröffentlicht in: Macedonian Pharmaceutical Bulletin, 2022, ISSN 1857-8969
Herausgeber: Skopje Makedonsko farmacevtsko društvo
DOI: 10.33320/maced.pharm.bull.2022.68.03.006

Sex differences in COVID-19: the role of androgens in disease severity and progression

Autoren: Mohamed S. Mohamed, Thiago C. Moulin, Helgi B. Schiöth
Veröffentlicht in: Endocrine, Ausgabe 71/1, 2021, Seite(n) 3-8, ISSN 1355-008X
Herausgeber: Springer Link
DOI: 10.1007/s12020-020-02536-6

Leistungen

Veröffentlichungen

Diese Seite teilen

Herunterladen