Superconducting Mass Spectrometry and Molecule Analysis | SuperMaMa | Project | Ergebnisse | H2020 | CORDIS

Leistungen

Iterated SNWD design, specification, fabrication, delivery

Iterated SNWD design specification fabrication delivery

Optimized ion steering and Chip cleaning in cryochamber

SNWD sensitivity to internal molecular energy

Report on SNWD sensitivity to internal molecular energy

Validation 5: Peptides with green PCTs synthesized and validated
Validation 3: peptides/proteins detected by 8-pixel SNWA prototype

Validation 3 peptidesproteins detected by 8pixel SNWA prototype

Validation 9: Preparation of a mass selected neutral protein beam

Validation 9 Preparation of a mass selected neutral protein beam

128-pixel array prototype, shipped Vienna

128pixel packaged array prototype shipped to Vienna

Report on reliability in UHV, thermal cycling, molecular irradiation

Report on reliability in UHV thermal cycling molecular irradiation

Strategies for increasing density and collimation of neutral protein beams
Validation 2: Optimized SNWD tested with proteins

Validation 2 Optimized SNWD tested with proteins

Validation 11: SNWD assisted detection of absorption in neutral macromolecules

Validation 11 SNWD assisted detection of absorption in neutral macromolecules

Validation 6: Peptides with blue PCTs synthesized and validated

Validation 6 Peptides with blue PCTs synthesized and validated

Complete mass spectrometer design: selectors, optics zones, cryogenic chamber
8-pixel packaged array prototype, shipped to Vienna

8pixel packaged array prototype shipped to Vienna

Validation 8: SNWD detection of singly-charged mass selected 100 kDa proteins

Validation 8 SNWD detection of singlycharged mass selected 100 kDa proteins

Validation 10: SNWD assisted detection of absorption in biopolymer ions

Validation 10 SNWD assisted detection of absorption in biopolymer ions

Project website

Up-to date information on the project

Veröffentlichungen

A 0.32 × 0.12 mm^2 Cryogenic BiCMOS 0.1–8.8 GHz Low Noise Amplifier Achieving 4 K Noise Temperature for SNWD Readout

Autoren: Y. Peng, J. Benserhir, M. Castaneda, A. Fognini, C. Bruschini and E. Charbon
Veröffentlicht in: IEEE Transactions on Microwave Theory and Techniques, 2024, ISSN 1557-9670
Herausgeber: IEEE
DOI: 10.1109/tmtt.2024.3354828

Highly sensitive single-molecule detection in slow protein ion beams

Autoren: M. Strauß, A. Shayeghi, M.F.X. Mauser, P. Geyer, T. Kostersitz, J. Salapa, O. Dobrovolskiy, S. Daly, J. Commandeur, Y. Hua, V. Köhler, M. Mayor, J. Benserhir, C. Bruschini, E. Charbon, M. Castaneda, M. Gevers, R. Gourgues, N. Kalhor, A. Fognini, and M. Arndt
Veröffentlicht in: Science Advances, Ausgabe 9, 2023, Seite(n) 48, ISSN 2375-2548
Herausgeber: American Society Association for the Advancement of Science
DOI: 10.1126/sciadv.adj2801

Giving the Green Light to Photochemical Uncaging of Large Biomolecules in High Vacuum

Autoren: Yong Hua, Marcel Strauss, Sergey Fisher, Martin F. X. Mauser, Pierre Manchet, Martina Smacchia, Philipp Geyer, Armin Shayeghi, Michael Pfeffer, Tim Henri Eggenweiler, Steven Daly, Jan Commandeur, Marcel Mayor, Markus Arndt, Tomáš Šolomek, and Valentin Köhler
Veröffentlicht in: JACS, 2023, ISSN 2691-3704
Herausgeber: ACS Publications
DOI: 10.1021/jacsau.3c00351

Neutralization of an Oxytocin Derivative by 355 nm Photocleavage in High Vacuum

Autoren: Yong Hua, Daniel Häussinger, Marcel Mayor, Valentin Köhler, Marcel Strauss, Martin F. X. Mauser, Tim Kostersitz, Philipp Geyer, Markus Arndt
Veröffentlicht in: Helvetica Chimica Acta, Ausgabe 108, 2025, ISSN 0018-019X
Herausgeber: Verlag Helvetica Chimica Acta
DOI: 10.1002/hlca.202400167

Superconducting Nanowire Detection of Neutral Atoms and Molecules via Their Internal and Kinetic Energy in the eV Range

Autoren: M. Strauß, R. Gourgues, M. F. X. Mauser, L. Kulman, M. Castaneda, A. Fognini, A. Shayeghi, P. Geyer, M. Arndt
Veröffentlicht in: Advanced Physics Research, Ausgabe 4, 2025, ISSN 2751-1200
Herausgeber: Wiley
DOI: 10.1002/apxr.202400133

Giving the green light to photochemical uncaging of large biomolecules in high vacuum

Autoren: Yong Hua, Marcel Strauss, Sergey Fisher, Martin F. X. Mauser , Pierre Manchet, Martina Smacchia, Philipp Geyer, Armin Shayeghi, Michael Pfeffer, Tim Henri Eggenweiler, Steven Daly, Jan Commandeur, Marcel Mayor, Markus Arndt, Tomáš Šolomek, Valentin Köhler
Veröffentlicht in: 2023
Herausgeber: -
DOI: 10.26434/chemrxiv-2023-mgqg3

Click, Lock & Dye: a chromogenic handle for selective cysteine modification

Autoren: Yong Hua, Zhi Zou, Alessandro Prescimone,Thomas R. Ward, Marcel Mayor, Valentin Köhler
Veröffentlicht in: 2023
Herausgeber: ChemRxiv

Superconducting quantum detectors and single photon charge control for mass spectrometry

Autoren: Marcel Strauß, Armin Shayeghi, Martin Mauser, Pierre Manchet, Martina Smacchia, Julia Salapa, Tim Kostersitz, Philipp Geyer, Steven Daly, Jan Commandeur, Yong Hua, Alfredo Di Silvestro, Marcel Mayor, Valentin Köhler, Jad Benserhir, Claudio Bruschini, Edoardo Charbon, Mario Castaneda, Monique Gevers, Ronan Gourgues, Nima Kalhor, Andreas Fognini, Markus Arndt
Veröffentlicht in: Proceedings of SPIE - Proceedings Volume 12447, Quantum Sensing, Imaging, and Precision Metrology; 124470I (2023), 2023, Seite(n) 124470I-1 to 124470I-7
Herausgeber: Proceedings of SPIE
DOI: 10.1117/12.2657258

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