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C-H Activation for Industrial Renewal

Descripción del proyecto

Red europea de formación sobre síntesis orgánica sostenible

La activación de enlaces de carbono-hidrógeno (C-H) es uno de los campos de la química orgánica que se está desarrollando más rápidamente, si bien su aplicación para fines industriales sigue siendo limitada. Esto se debe principalmente a la falta de cooperación entre el mundo académico y el industrial, así como a la disponibilidad limitada de jóvenes expertos en este campo. El proyecto financiado con fondos europeos CHAIR es una red europea de investigación dedicada a abordar estas cuestiones. La red reúne a nueve instituciones académicas de renombre y seis socios industriales, y tiene como objetivo fundamental establecer una base sólida que permita impulsar la utilización industrial de la activación de C-H. Se integrará a quince investigadores noveles y quince investigadores de alto nivel en proyectos de investigación fundamental para mostrar el potencial de la activación de enlaces de C-H.

Objetivo

C-H activation is one of the most rapidly expanding areas of molecular chemistry and has emerged as an increasingly viable tool. Despite clear benefits offered by the C-H activation for sustainable and eco-responsible synthesis, its industrial applications are scarce. The lack of its widespread implementation in the industrial sector is due to multiple factors, amongst which the major reasons are a) the limited interactions between academia and industrial practitioners, and b) a limited number of young scientists with a strong expertise in the domain. CHAIR is aimed to specifically address these issues. CHAIR represents a unique European Research Network, combining nine renowned academic research groups and six industrial partners, strongly motivated to settle a solid basement for profound embedment of the C-H activation in an industrial environment. To achieve this ambitious goal 15 ESRs and 15 advanced scientists will be mobilized to implement direct C-H functionalization in industry, including both lead development and process chemistry. Fundamental research projects will be conducted to showcase the potential of the C-H activation to 1) speed up lead-to-hit optimization in pharmaceutical industries; 2) rapidly access molecular diversity; 3) assemble advanced materials; 4) convert raw materials into valuable building blocks; 5) bring new techniques to easily implement C-H activation based protocols for large-scale production. Development of these projects, combined with the scientific training and close collaborations within the CHAIR consortiums through specific secondments will provide 15 ESRs with unique competences in this edge-cutting field. Trainings on personal development, career development and societal/business aspects will complement their unique education, providing them with far-reaching and complementary competences to become future key actors of chemical industries in charge of the modernization of chemical and pharmaceutical industries.

Coordinador

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Aportación neta de la UEn
€ 824 406,12
Dirección
RUE MICHEL ANGE 3
75794 Paris
Francia

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Región
Ile-de-France Ile-de-France Paris
Tipo de actividad
Research Organisations
Enlaces
Coste total
€ 824 406,12

Participantes (13)