Description du projet
Réseau européen de formation sur la synthèse organique durable
L’activation de la liaison carbone-hydrogène (C–H) est l’un des domaines les plus développés en chimie organique, mais son application à des fins industrielles reste limitée. Cela est principalement dû au manque de coopération entre les universités et l’industrie et au trop faible nombre de jeunes experts dans le domaine. Le projet CHAIR, financé par l’UE, est un réseau de recherche européen dont le but est de pallier à ces lacunes. Le réseau rassemble neuf instituts de recherche universitaires renommés et six partenaires industriels, fortement motivés pour établir une base solide qui permettra à l’activation industrielle des liaisons C–H de trouver une utilisation plus large. Quinze chercheurs en début de carrière et quinze chercheurs seniors seront engagés dans des projets de recherche fondamentale pour mettre en valeur le potentiel de l’activation des liaisons C–H.
Objectif
C-H activation is one of the most rapidly expanding areas of molecular chemistry and has emerged as an increasingly viable tool. Despite clear benefits offered by the C-H activation for sustainable and eco-responsible synthesis, its industrial applications are scarce. The lack of its widespread implementation in the industrial sector is due to multiple factors, amongst which the major reasons are a) the limited interactions between academia and industrial practitioners, and b) a limited number of young scientists with a strong expertise in the domain. CHAIR is aimed to specifically address these issues. CHAIR represents a unique European Research Network, combining nine renowned academic research groups and six industrial partners, strongly motivated to settle a solid basement for profound embedment of the C-H activation in an industrial environment. To achieve this ambitious goal 15 ESRs and 15 advanced scientists will be mobilized to implement direct C-H functionalization in industry, including both lead development and process chemistry. Fundamental research projects will be conducted to showcase the potential of the C-H activation to 1) speed up lead-to-hit optimization in pharmaceutical industries; 2) rapidly access molecular diversity; 3) assemble advanced materials; 4) convert raw materials into valuable building blocks; 5) bring new techniques to easily implement C-H activation based protocols for large-scale production. Development of these projects, combined with the scientific training and close collaborations within the CHAIR consortiums through specific secondments will provide 15 ESRs with unique competences in this edge-cutting field. Trainings on personal development, career development and societal/business aspects will complement their unique education, providing them with far-reaching and complementary competences to become future key actors of chemical industries in charge of the modernization of chemical and pharmaceutical industries.
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MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)Coordinateur
75794 Paris
France