SuperCol: Rational design of super-selective and responsive colloidal particles for biomedical applications

Informazioni relative al progetto

SuperCol

ID dell’accordo di sovvenzione: 860914

DOI

10.3030/860914

Progetto chiuso

Data della firma CE 11 Settembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2023

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 058 814,96

Contributo UE

€ 4 058 814,96

Coordinato da

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

Overall recruitment report

Websites, patent fillings, videos etc. (1)

website

First version of external SUPERCOL website online

Other (4)

Awarding of doctoral degrees

Awarding of doctoral degrees, all beneficiaries are in lead and provide the degree at their respective University

Call for applications
Software to correct mislocalisation

Software to correct mislocalisation based on optical parameters and particle geometry

Supervisory board of the network

Supervisory board instated and added to website

Pubblicazioni

Peer reviewed articles (32)

Correlative imaging for polymer science

Autori: Yuyang Wang, Heiner Friedrich, Ilja K. Voets, Peter Zijlstra, Lorenzo Albertazzi
Pubblicato in: Journal of Polymer Science, Numero 59, 2023, Pagina/e 1232-1240, ISSN 2642-4150
Editore: Wiley
DOI: 10.1002/pol.20210013

Pathways and challenges towards a complete characterization of microgels.

Autori: Frank Scheffold
Pubblicato in: Nature Communications, 2020, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-17774-5

Electrochemical Determination of Gallic Acid in Tea Samples Using Pyramidal Pt Nanoparticles

Autori: Tiziano Di Giulio, Maria Antonieta Ramírez‐Morales, Valentina Mastronardi, Giuseppe Mele, Rosaria Brescia, Pier Paolo Pompa, Cosimino Malitesta, Giuseppe Egidio De Benedetto, Mauro Moglianetti, Maria Ada Malvindi, Elisabetta Mazzotta
Pubblicato in: Advanced Electronic Materials, Numero 11, 2025, ISSN 2199-160X
Editore: Wiley
DOI: 10.1002/aelm.202400792

Protein aggregation monitoring in cells under oxidative stress: a novel fluorescent probe based on a 7-azaindole-BODIPY derivative

Autori: Diego Herrera-Ochoa, Iván Llano, Consuelo Ripoll, Pierre Cybulski, Martin Kreuzer, Susana Rocha, Eva M. García-Frutos, Iván Bravo, Andrés Garzón-Ruiz
Pubblicato in: Journal of Materials Chemistry B, Numero 12, 2025, Pagina/e 7577-7590, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d4tb00567h

Comparing the Structure of Microgels at Liquid–Liquid and Solid–Liquid Interfaces

Autori: Rodrigo Rivas-Barbosa, Fabrizio Camerin, Jacopo Vialetto, Shivaprakash N. Ramakrishna, Lucio Isa, Emanuela Zaccarelli
Pubblicato in: Langmuir, Numero 41, 2025, Pagina/e 16674-16684, ISSN 0743-7463
Editore: American Chemical Society
DOI: 10.1021/acs.langmuir.5c02599

IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density

Autori: Shanil Gandhi, Xhorxhina Shaulli, Jeppe Fock, Frank Scheffold, Rodolphe Marie
Pubblicato in: APL Bioengineering, Numero 8, 2024, ISSN 2473-2877
Editore: American Physical Society
DOI: 10.1063/5.0196224

Point-Spread Function Deformations Unlock 3D Localization Microscopy on Spherical Nanoparticles

Autori: Teun A.P.M. Huijben, Sarojini Mahajan, Masih Fahim, Peter Zijlstra, Rodolphe Marie, Kim I. Mortensen
Pubblicato in: ACS Nano, Numero 18, 2025, Pagina/e 29832-29845, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.4c09719

Ion and Molecular Sieving With Ultrathin Polydopamine Nanomembranes

Autori: Jiyao Yu, Tommaso Marchesi D'Alvise, Iain Harley, Adam Krysztofik, Ingo Lieberwirth, Przemyslaw Pula, Pawel W. Majewski, Bartlomiej Graczykowski, Johannes Hunger, Katharina Landfester, Seah Ling Kuan, Rachel Shi, Christopher V. Synatschke, Tanja Weil
Pubblicato in: Advanced Materials, Numero 36, 2024, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202401137

DNA Self-Assembly of Single Molecules with Deterministic Position and Orientation

Autori: Aleksandra K. Adamczyk, Teun A. P. M. Huijben, Miguel Sison, Andrea Di Luca, Germán Chiarelli, Stefano Vanni, Sophie Brasselet, Kim I. Mortensen, Fernando D. Stefani, Mauricio Pilo-Pais, and Guillermo P. Acuna
Pubblicato in: ACS Nano, 2022, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.2c06936

Rate-Engineered Plasmon-Enhanced Fluorescence for Real-Time Microsecond Dynamics of Single Biomolecules

Autori: Sjoerd W. Nooteboom, Kasper R. Okholm, Vincenzo Lamberti, Bas Oomen, Duncan S. Sutherland, Peter Zijlstra
Pubblicato in: Nano Letters, Numero 24, 2024, Pagina/e 11641-11647, ISSN 1530-6984
Editore: American Chemical Society
DOI: 10.1021/acs.nanolett.4c03220

Supramolecular assembly guided by photolytic redox cycling

Autori: Patrick Roth, Raphael Meyer, Iain Harley, Katharina Landfester, Ingo Lieberwirth, Manfred Wagner, David Y. W. Ng, Tanja Weil
Pubblicato in: Nature Synthesis, Numero 2, 2023, Pagina/e 980-988, ISSN 2731-0582
Editore: Springer Nature
DOI: 10.1038/s44160-023-00343-1

Membrane Manipulation of Giant Unilamellar Polymer Vesicles with a Temperature‐Responsive Polymer

Autori: Marina de Souza Melchiors, Tsvetomir Ivanov, Iain Harley, Claudia Sayer, Pedro H. H. Araújo, Lucas Caire da Silva, Calum T. J. Ferguson, Katharina Landfester
Pubblicato in: Angewandte Chemie International Edition, Numero 61, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202207998

Single-Molecule Multivalent Interactions Revealed by Plasmon-Enhanced Fluorescence

Autori: Kasper R. Okholm, Sjoerd W. Nooteboom, Johan Nygaard Vinther, Vincenzo Lamberti, Swayandipta Dey, Ebbe Sloth Andersen, Peter Zijlstra, Duncan S. Sutherland
Pubblicato in: ACS Nano, Numero 18, 2025, Pagina/e 35429-35442, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.4c12600

Polymer Nano‐Carrier‐Mediated Gene Delivery: Visualizing and Quantifying DNA Encapsulation Using dSTORM

Autori: Xhorxhina Shaulli, Aura Maria Moreno‐Echeverri, Mariza Andoni, Eileen Waeber, Shivaprakash N. Ramakrishna, Cornelia Fritsch, Dimitri Vanhecke, Barbara Rothen‐Rutishauser, Frank Scheffold
Pubblicato in: Small, Numero 21, 2025, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202405929

Probing Temperature Responsivity of Microgels and Its Interplay with a Solid Surface by Super-Resolution Microscopy and Numerical Simulations.

Autori: Xhorxhina Shaulli, Rodrigo Rivas-Barbosa, Maxime J. Bergman, Chi Zhang, Nicoletta Gnan, Frank Scheffold, and Emanuela Zaccarelli
Pubblicato in: ACS Nano, 2023, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.2c07569

Link between morphology, structure and interactions of composite microgels

Autori: Rodrigo Rivas-Barbosa, José Ruiz-Franco, Mayra A. Lara-Peña, Jacopo Cardellini, Angel Licea-Claverie, Fabrizio Camerin, Emanuela Zaccarelli, Marco Laurati
Pubblicato in: Macromolecules, 2021, ISSN 0024-9297
Editore: American Chemical Society
DOI: 10.1021/acs.macromol.1c02171

Tailoring reactive handles on the surface of nanoparticles for covalent conjugation of biomolecules

Autori: Francesca Mazzotta, Sharafudheen Pottanam Chali, Ingo Lieberwirth, Calum T. J. Ferguson, Katharina Landfester
Pubblicato in: Polymer Chemistry, Numero 16, 2025, Pagina/e 433-440, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/d4py01119h

Coupling Single Molecules to DNA-Based Optical Antennas with Position and Orientation Control

Autori: Aleksandra K. Adamczyk, Fangjia Zhu, Daniel Schäfer, Yuya Kanehira, Sergio Kogikoski, Ilko Bald, Sebastian Schlücker, Karol Kołątaj, Fernando D. Stefani, Guillermo P. Acuna
Pubblicato in: ACS Photonics, Numero 11, 2024, Pagina/e 5267-5272, ISSN 2330-4022
Editore: American Chemical Society
DOI: 10.1021/acsphotonics.4c01506

An Outer Membrane‐Inspired Polymer Coating Protects and Endows <i>Escherichia coli</i> with Novel Functionalities

Autori: Andrea Belluati, Iain Harley, Ingo Lieberwirth, Nico Bruns
Pubblicato in: Small, Numero 19, 2023, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202303384

Practical considerations for plunge freezing samples over 40 °C for Cryo-EM

Autori: Iain Harley, Francesca Mazzotta, Xhorxhina Shaulli, Frank Scheffold, Katharina Landfester, Ingo Lieberwirth
Pubblicato in: Micron, Numero 188, 2024, Pagina/e 103745, ISSN 0968-4328
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.micron.2024.103745

Continuous Monitoring Biosensing Mediated by Single-Molecule Plasmon-Enhanced Fluorescence in Complex Matrices

Autori: Vincenzo Lamberti, Mathias Dolci, Peter Zijlstra
Pubblicato in: ACS Nano, 2024, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.3c12428

Concentration and temperature dependent interactions and state diagram of dispersions of copolymer microgels

Autori: José Ruiz-Franco, Rodrigo Rivas-Barbosa, Mayra A. Lara-Peña, José R. Villanueva-Valencia, Angel Licea-Claverie, Emanuela Zaccarelli, Marco Laurati
Pubblicato in: Soft Matter, Numero 19, 2024, Pagina/e 3614-3628, ISSN 1744-683X
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sm00120b

Dual-color core–shell silica nanosystems for advanced super-resolution biomedical imaging

Autori: Maria Antonieta Ramirez-Morales, Elisa De Luca, Chiara Coricciati, Alberto Rainer, Giuseppe Gigli, Giuseppe Mele, Pier Paolo Pompa, and Maria Ada Malvindi
Pubblicato in: Nanoscale Advances, 2023, ISSN 2516-0230
Editore: Royal Society of Chemistry
DOI: 10.1039/d3na00310h

Single-shot Stokes polarimetry of plasmon-coupled single-molecule fluorescence

Autori: Sarojini Mahajan, Yuyang Wang, Teun A.P.M. Huijben, Rodolphe Marie, Peter Zijlstra
Pubblicato in: Nanophotonics, 2025, ISSN 2192-8606
Editore: Walter de Gruyter GmbH
DOI: 10.1515/nanoph-2025-0352

Biomolecular interactions on densely coated nanoparticles: a single-molecule perspective

Autori: Swayandipta Dey,Rodrigo Rivas-Barbosa,Francesco Sciortino, Emanuela Zaccarelli and Peter Zijlstra
Pubblicato in: Nanoscale, 2024, ISSN 2040-3372
Editore: Royal Society of Chemistry
DOI: 10.1039/d3nr06140j

Chaperone‐Derived Copper(I)‐Binding Peptide Nanofibers Disrupt Copper Homeostasis in Cancer Cells

Autori: M. T. Jeena, Julian Link, Jian Zhang, Iain Harley, Petri Turunen, Robert Graf, Manfred Wagner, Luis Andre Baptista, Hendrik R. A. Jonker, Liyang Cui, Ingo Lieberwirth, Katharina Landfester, Jianghong Rao, David Y. W. Ng, Tanja Weil
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2025, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202412477

Assembly of biomimetic microreactors using caged-coacervate droplets

Autori: Arjaree Jobdeedamrong, Shoupeng Cao, Iain Harley, Daniel Crespy, Katharina Landfester, Lucas Caire da Silva
Pubblicato in: Nanoscale, Numero 15, 2024, Pagina/e 2561-2566, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/d2nr05101j

Nanoparticle characterisation <i>via</i> 2D classification using single particle averaging

Autori: Iain Harley, Anke Kaltbeitzel, Francesca Mazzotta, Kaloian Koynov, Sarah S. Lembke, Thao P. Doan-Nguyen, Katharina Landfester, Ingo Lieberwirth
Pubblicato in: Nanoscale Horizons, Numero 10, 2025, Pagina/e 1642-1652, ISSN 2055-6756
Editore: Royal Society of Chemistry (RSC)
DOI: 10.1039/d5nh00094g

Versatile and Robust Method for Antibody Conjugation to Nanoparticles with High Targeting Efficiency

Autori: Indra Van Zundert, Maria Bravo, Olivier Deschaume, Pierre Cybulski, Carmen Bartic, Johan Hofkens, Hiroshi Uji-i, Beatrice Fortuni, and Susana Rocha
Pubblicato in: Pharmaceutics, 2021, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13122153

Nanoparticle Accumulation and Penetration in 3D Tumor Models: the Effect of Size, Shape, and Surface Charge

Autori: Pierre Cybulski, Maria Bravo, Jim Jui-Kai Chen, Indra Van Zundert, Sandra Krzyzowska, Farsai Taemaitree, Hiroshi Uji-i, Johan Hofkens, Susana Rocha, Beatrice Fortuni
Pubblicato in: Frontiers in Cell and Developmental Biology, 2025, ISSN 2296-634X
Editore: Frontiers
DOI: 10.1101/2024.12.06.626955

Gaining control on optical force by the stimulated-emission resonance effect

Autori: Tetsuhiro Kudo, Boris Louis, Hikaru Sotome, Jui-Kai Chen, Syoji Ito, Hiroshi Miyasaka, Hiroshi Masuhara, Johan Hofkens and Roger Bresolí-Obach
Pubblicato in: Chemical Science, 2023, ISSN 2041-6539
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc01927f

Aerobic Photobiocatalysis Enabled by Combining Core–Shell Nanophotoreactors and Native Enzymes

Autori: Wenxin Wei, Francesca Mazzotta, Ingo Lieberwirth, Katharina Landfester, Calum T. J. Ferguson, and Kai A. I. Zhang:
Pubblicato in: Journal of the American Chemical Society, 2022, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.2c00576

Other (6)

Chaperone-derived Cu(I)-binding peptide nanofibers disrupt copper homeostasis in cancer cells

Autori: Jeena M. Thekkeyil ,Julian Link ,Jian Zhang ,Luis Andre Baptista ,Hendrik R. A. Jonker ,Iain Harley ,Petri Turunen ,Liyang Cui ,Ingo Lieberwirth ,Katharina Landfester ,Robert Graf ,Manfred Wagner ,Jianghong Rao ,David Ng ,Tanja Weil
Pubblicato in: 2024
Editore: ChemRxiv
DOI: 10.26434/chemrxiv-2024-v04mz

Kinetics and dynamics of single-molecule multivalent interactions revealed by plasmon-enhanced fluorescence

Autori: Kasper R. Okholm, Sjoerd W. Nooteboom, Vincenzo Lamberti, Swayandipta Dey, Peter Zijlstra, Duncan S. Sutherland
Pubblicato in: 2024
Editore: bioRxiv
DOI: 10.1101/2023.12.08.570798

A Fluorescent Probe for Protein Misfolding and Aggregation Due to Oxidative Stress Based on a 7-Azaindole-BODIPY Derivative

Autori: Diego Herrera-Ochoa ,Iván Llano ,Consuelo Ripoll ,Pierre Cybulski ,Martin Kreuzer,Susana Rocha ,Eva M. García-Frutos ,Iván Bravo ,Andrés Garzón Ruiz
Pubblicato in: 2024
Editore: ChemRxiv
DOI: 10.26434/chemrxiv-2024-94b66

Exact particle-enhanced point-spread function unlocks 3D super-resolution localization microscopy on nanoparticles

Autori: Teun A. P. M. Huijben, Sarojini Mahajan, Peter Zijlstra, Rodolphe Marie, Kim I. Mortensen
Pubblicato in: 2023
Editore: Arxiv
DOI: 10.48550/arxiv.2306.08148

Towards full control of molecular exciton energy transfer via FRET in DNA origami assemblies

Autori: Aleksandra K. Adamczyk, Teun A.P.M. Huijben, Karol Kolataj, Fangjia Zhu, Rodolphe Marie, Fernando D. Stefani, Guillermo P. Acuna
Pubblicato in: 2024
Editore: arxiv
DOI: 10.48550/arxiv.2402.06292

Towards full control of molecular exciton energy transfer via FRET in DNA origami assemblies

Autori: Aleksandra K. Adamczyk, Teun A.P.M. Huijben, Karol Kolataj, Fangjia Zhu, Rodolphe Marie, Fernando D. Stefani, Guillermo P. Acuna
Pubblicato in: Numero 1, 2025
Editore: arxiv

Non-peer reviewed articles (1)

Correction to “Aerobic Photobiocatalysis Enabled by Combining Core–Shell Nanophotoreactors and Native Enzymes”

Autori: Wenxin Wei, Francesca Mazzotta, Ingo Lieberwirth, Katharina Landfester, Calum T. J. Ferguson, Kai A. I. Zhang
Pubblicato in: Journal of the American Chemical Society, Numero 145, 2023, Pagina/e 3826-3826, ISSN 0002-7863
Editore: American Chemical Society
DOI: 10.1021/jacs.3c00723