Antimicrobial Integrated Methodologies for orthopaedic applications

Informazioni relative al progetto

AIMed

ID dell’accordo di sovvenzione: 861138

DOI

10.3030/861138

Progetto chiuso

Data della firma CE 17 Gennaio 2020

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 3 845 532,12

Contributo UE

€ 3 845 532,12

Coordinato da

THE UNIVERSITY OF BIRMINGHAM
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (10)

Award of PhD degree

D8.8 Award of PhD degree (after M42

Recruitment completed

D9.4 Recruitment completed (M12)

Research papers

D7.8 Research papers (M41)

Article in Materials Today

D7.7 Article in Materials Today (M40);

Birmingham Science Festival

D7.4 Birmingham Science Festival (M30

Vacancies advertisement

D9.2 Vacancies advertisement (M1

European Society for Biomaterials 2022

D7.6 European Society for Biomaterials 2022 (M36);

Operational network website and internet communication

D9.5 Operational network website and internet communication live (M2);

Bioceramics 32

D7.2 Bioceramics 32 (M12);

Outreach at UoB START

D7.3 Outreach at UoB START (M17);

Open Research Data Pilot (1)

Data management plan

A data management plan will be in place that will ensure all metadata accessible via UoB.

Documents, reports (2)

Open report on sterilization study

D6.4 Open report on sterilization study (M41);

Open report on drug release study

D6.5 Open report on drug release study (M41)

Pubblicazioni

Peer reviewed articles (24)

Materials derived from the human elastin-like polypeptide fusion with an antimicrobial peptide strongly promote cell adhesion

Autori: Laura Colomina-Alfaro, Paola Sist, Paola D’Andrea, Ranieri Urbani, Silvia Marchesan, Artemis Stamboulis, Antonella Bandiera
Pubblicato in: Journal of Materials Chemistry B, Numero 12, 2024, Pagina/e 8966-8976, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d4tb00319e

Development of Femtosecond Laser-Engineered beta-Tricalcium Phosphate (beta-TCP) Biomimetic Templates for Orthopaedic Tissue Engineering

Autori: Daskalova, A (Daskalova, Albena) [1] ; Angelova, L (Angelova, Liliya) [1] ; Trifonov, A (Trifonov, Anton) [2] ; Lasgorceix, M (Lasgorceix, Marie) [3] , [4] , [5] ; Hocquet, S (Hocquet, Stephane) [4] , [5] , [6] ; Minne, M (Minne, Mendy) [7] ; Declercq, H (Declercq, Heidi) [7] ; Leriche, A (Leriche, Anne) [3] , [4] , [5] ; Aceti, D (Aceti, Dante) [1] ; Buchvarov, I (Buchvarov, Ivan) [2]
Pubblicato in: Applied Science, 2021, ISSN 2076-3417
Editore: MDPI
DOI: 10.3390/app11062565

Surface structuring of β-TCP and transition to α-TCP induced by femtosecond laser processing

Autori: DM Aceti, E Filipov, L Sotelo, M Lasgorceix, A Leriche, I Buchvarov, A Daskalova
Pubblicato in: Journal of Physics: Conference Series, 2022, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2487/1/012043

Analysis of femtosecond microstructured Poly Lactic Acid temporary cell scaffolds, spin-coated with Chitosan or Hydroxyapatite

Autori: L. Angelova; A. Daskalova; E. Filipov; R. Mincheva; X. Carette; D. Miano; D. Aceti; A. Trifonov; I. Buchvarov
Pubblicato in: Optical and Quantum Electronics, 2022, ISSN 0306-8919
Editore: Kluwer Academic Publishers
DOI: 10.1007/s11082-022-03970-8

Ultra-short laser structuring of 3D-microfabricated non-resorbable polystyrene polymer to anchor cellular adhesion

Autori: L Angelova, E Filipov, DM Aceti, Al Zhelyazkova, I Buchvarov, A Daskalova
Pubblicato in: Journal of Physics: Conference Series, 2023, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2487/1/012001

Processing and interpretation of core-electron XPS spectra o complex plasma-treated polyethylene-based surfaces using a theoretical peak model

Autori: Bruggeman, M (Bruggeman, Marc) [1] ; Zelzer, M (Zelzer, Mischa) [2] ; Dong, HS (Dong, Hanshan) [3] ; Stamboulis, A (Stamboulis, Artemis) [1]
Pubblicato in: Surface and Interface Analysis, 2022, ISSN 1096-9918
Editore: Wiley
DOI: 10.1002/sia.7125

Comparison of the activity of two elastin-like recombinant carriers fused to the antimicrobial peptide indolicidin

Autori: Laura Colomina-Alfaro, Paola Sist, Angela Ivask, Brenda Raid, Hanna Ainelo, Abeer Shaalan, Lucy Di Silvio, Ranieri Urbani, Artemis Stamboulis, Antonella Bandiera
Pubblicato in: International Journal of Biological Macromolecules, Numero 283, 2024, Pagina/e 137682, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2024.137682

Self-Assembly of Homo- and Hetero-Chiral Cyclodipeptides into Supramolecular Polymers towards Antimicrobial Gels

Autori: Beatrice Rosetti; Erica Scarel; Laura Colomina-Alfaro; Simone Adorinni; Giovanni Pierri; Ottavia Bellotto; Kevin Mamprin; Maurizio Polentarutti; Antonella Bandiera; Consiglia Tedesco; Silvia Marchesan
Pubblicato in: Polymers; Volume 14; Numero 21; Pages: 4554, 2022, Pagina/e 4554, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym14214554

Biomimetic Hierarchical Structuring of PLA by Ultra-Short Laser Pulses for Processing of Tissue Engineered Matrices: Study of Cellular and Antibacterial Behavior.

Autori: A. Daskalova; L. Angelova; Emil Filipov; Dante Aceti; Rosica Mincheva; Xavier Carrete; Halima Kerdjoudj; Marie Dubus; Julie Chevrier; A. Trifonov; Ivan Buchvarov
Pubblicato in: Polymers, Numero 13(15), 2021, Pagina/e 2577, ISSN 2073-4360
Editore: MDPI
DOI: 10.48550/arxiv.2112.05026

Femtosecond Laser-Engineered β-TCP Scaffolds: A Comparative Study of Green-Synthesized AgNPs vs. Ion Doping Against S. aureus for Bone Regeneration

Autori: Marco Oliveira, Liliya Angelova, Georgi Avdeev, Liliana Grenho, Maria Helena Fernandes, Albena Daskalova
Pubblicato in: International Journal of Molecular Sciences, Numero 26, 2025, Pagina/e 4888, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms26104888

A Versatile Elastin‐Like Carrier for Bioactive Antimicrobial Peptide Production and Delivery

Autori: Laura ColominaAlfaro, Paola Sist, Silvia Marchesan, Ranieri Urbani, Artemis Stamboulis, Antonella Bandiera
Pubblicato in: Macromolecular Bioscience. Wiley, 2023, ISSN 1616-5187
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202300236

Bone Cell Exosomes and Emerging Strategies in Bone Engineering

Autori: Vig, S (Vig, Sanjana) [1] , [2] ; Fernandes, MH (Fernandes, Maria Helena) [1] , [2]
Pubblicato in: Biomedicines, 2022, ISSN 2227-9059
Editore: MDPI
DOI: 10.3390/biomedicines10040767

Single-Step Process for Titanium Surface Micro- and Nano-Structuring and In Situ Silver Nanoparticles Formation by Ultra-Short Laser Patterning

Autori: Aceti, DM (Aceti, Dante Maria) [1] ; Filipov, E (Filipov, Emil) [1] ; Angelova, L (Angelova, Liliya) [1] ; Sotelo, L (Sotelo, Lamborghini) [2] , [3] ; Fontanot, T (Fontanot, Tommaso) [4] ; Yousefi, P (Yousefi, Peyman) [2] , [4] ; Christiansen, S (Christiansen, Silke) [3] , [4] ; Leuchs, G (Leuchs, Gerd) [2] , [5] ; Stanimirov, S (Stanimirov, Stanislav) [6] ; Trifonov, A (Trifonov, Anton) [7] ; Buc
Pubblicato in: Materials, 2022, ISSN 1996-1944
Editore: MDPI Open Access Publishing
DOI: 10.3390/ma15134670

Corrosion behaviour of electropolished magnesium materials

Autori: Jessica Kloiber, Ulrich Schultheiß, Lamborghini Sotelo, George Sarau, Silke Christiansen, Sarkis Gavras, Norbert Hort, Helga Hornberger
Pubblicato in: Materials Today Communications, Numero 38, 2024, Pagina/e 107983, ISSN 2352-4928
Editore: Elsevier BV
DOI: 10.1016/j.mtcomm.2023.107983

Optimization of titanium and titanium alloy surface properties by ultra-short laser processing for improved antibacterial characteristics

Autori: DM Aceti, A Daskalova, L Angelova, E Filipov, L Sotelo, A Andreeva, A Trifonov, I Buchvarov
Pubblicato in: Journal of Physics: Conference Series, 2022, ISSN 1742-6588
Editore: Institute of Physics
DOI: 10.1088/1742-6596/2240/1/012040

In Vitro Analysis of Human Cartilage Infiltrated by Hydrogels and Hydrogel-Encapsulated Chondrocytes

Autori: Hannah Köck, Birgit Striegl, Annalena Kraus, Magdalena Zborilova, Silke Christiansen, Nicole Schäfer, Susanne Grässel, Helga Hornberger
Pubblicato in: Bioengineering, Numero 10, 2025, Pagina/e 767, ISSN 2306-5354
Editore: MDPI AG
DOI: 10.3390/bioengineering10070767

Investigation of Thin Silicone Films on Opaque Solid Surfaces Using Coherent Raman Scattering Imaging

Autori: Julian Naser, George Sarau, Jan Wrege, Silke Christiansen
Pubblicato in: Applied Spectroscopy, Numero 79, 2025, Pagina/e 1508-1517, ISSN 0003-7028
Editore: Society for Applied Spectroscopy
DOI: 10.1177/00037028251339495

Optimizing the Surface Structural and Morphological Properties of Silk Thin Films via Ultra-Short Laser Texturing for Creation of Muscle Cell Matrix Model

Autori: Angelova, L (Angelova, Liliya) [1] ; Daskalova, A (Daskalova, Albena) [1] ; Filipov, E (Filipov, Emil) [1] ; Vila, XM (Vila, Xavier Monforte) [2] , [3] ; Tomasch, J (Tomasch, Janine) [2] , [3] ; Avdeev, G (Avdeev, Georgi) [4] ; Teuschl-Woller, AH (Teuschl-Woller, Andreas H.) [2] , [3] ; Buchvarov, I (Buchvarov, Ivan) [5]
Pubblicato in: Polymers, 2022, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym14132584

Smart tools for antimicrobial peptides expression and application: The elastic perspective

Autori: Colomina-Alfaro, L (Colomina-Alfaro, Laura) [1] ; Marchesan, S (Marchesan, Silvia) [2] ; Stamboulis, A (Stamboulis, Artemis) [3] ; Bandiera, A (Bandiera, Antonella)
Pubblicato in: Biotechnology and Bioengineering, 2022, ISSN 1097-0290
Editore: Wiley
DOI: 10.1002/bit.28283

Ultra-Short Laser Surface Properties Optimization of Biocompatibility Characteristics of 3D Poly-ε-Caprolactone and Hydroxyapatite Composite Scaffolds

Autori: Albena Daskalova 1,*ORCID,Emil Filipov 1ORCID,Liliya Angelova 1ORCID,Radostin Stefanov 2,Dragomir Tatchev 3ORCID,Georgi Avdeev 3ORCID,Lamborghini Sotelo 4,5,Silke Christiansen 4,George Sarau 4,6ORCID,Gerd Leuchs 5,Ekaterina Iordanova 7 and Ivan Buchvarov 8
Pubblicato in: Materials, 2021, Pagina/e 14(24) 7513, ISSN 1996-1944
Editore: MDPI Open Access Publishing
DOI: 10.3390/ma14247513

Physicochemical Characterization of a Biomimetic, Elastin-Inspired Polypeptide with Enhanced Thermoresponsive Properties and Improved Cell Adhesion

Autori: Antonella Bandiera, Laura Colomina-Alfaro, Paola Sist, Giovanna Gomez d'Ayala, Federica Zuppardi, Pierfrancesco Cerruti, Ovidio Catanzano, Sabina Passamonti, Ranieri Urbani
Pubblicato in: American Chemical Society, 2023, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.3c00782

Toward Smart Biomimetic Apatite-Based Bone Scaffolds with Spatially Controlled Ion Substitutions

Autori: Cianflone, E.; Brouillet, F.; Grossin, D.; Soulié, J.; Josse, C.; Vig, S.; Fernandes, M.H.; Tenailleau, C.; Duployer, B.; Thouron, C.; Drouet, C.
Pubblicato in: Nanomaterials, Numero 13, 2023, Pagina/e 519, ISSN 2079-4991
Editore: MDPI
DOI: 10.3390/nano13030519

Investigating Potential Effects of Ultra-Short Laser-Textured Porous Poly-epsilon-Caprolactone Scaffolds on Bacterial Adhesion and Bone Cell Metabolism

Autori: Filipov, E (Filipov, Emil) [1] ; Angelova, L (Angelova, Liliya) [1] ; Vig, S (Vig, Sanjana) [2] , [3] ; Fernandes, MH (Fernandes, Maria Helena) [2] , [3] ; Moreau, G (Moreau, Gerard) [4] ; Lasgorceix, M (Lasgorceix, Marie) [4] ; Buchvarov, I (Buchvarov, Ivan) [5] ; Daskalova, A (Daskalova, Albena) [1]
Pubblicato in: Polymers, 2022, Pagina/e 14(12) 2382, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym14122382

Ultra-short laser processing of 3D bioceramic, porous scaffolds designed by freeze foaming method for orthopedic applications

Autori: Albena Daskalova, Matthias Ahlhelm, Liliya Angelova, Emil Filipov, Georgi Avdeev, Dragomir Tatchev, Maria-Helena Fernandes, Sanjana Vig, Ivan Buchvarov
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 12, 2024, ISSN 2296-634X
Editore: Frontiers Media SA
DOI: 10.3389/fcell.2024.1447979

Conference proceedings (3)

Different Strategies of Antimicrobial Peptides Production for Biomedical Applications

Autori: Cristina Cantallops-Vilà, Laura Colomina-Alfaro, Pietro Riccio, Hanieh Ijakipour, Edwige Meurice, Antonella Bandiera, and Artemis Stamboulis
Pubblicato in: Proceedings of the 36th European Peptide Symposium, 2023, ISBN 979-8-9872140-0-8
Editore: Proceedings of the 36th European Peptide Symposium
DOI: 10.17952/36eps.2022.039

Initial surface roughness influence on the generation of LIPSS on titanium and stainless steel and their effect on cell/bacteria viability

Autori: Lamborghini Sotelo, Tommaso Fontanot, Sanjana Vig, Maria Helena Fernandes, George Sarau, Gerd Leuchs, Silke Christiansen
Pubblicato in: Photonics West SPIE Proceedings, 2023
Editore: Photonics West SPIE Proceedings
DOI: 10.1117/12.2648921

Dynamics of development of laser-induced structures on the surface of a titanium alloy

Autori: Iana Fomicheva, Petr Druzhinin, Hans Amler, Wolfgang Schuesslbauer, Silke Christiansen, Gerd Leuchs
Pubblicato in: 2023
Editore: SPIE
DOI: 10.1117/12.2649015

Book chapters (1)

Antimicrobial Bioceramics for Biomedical Applications.

Autori: Pietro Riccio, Mohadeseh Zare, Diana Gomes, David Green, and Artemis Stamboulis.
Pubblicato in: Springer Series In Bio Materials, Science and Engineering, 2022
Editore: Springer Nature