Descrizione del progetto
Rendere l’analisi delle nanosospensioni più veloce e più conveniente
Le nanosospensioni sono un tipo di materiale critico che si trova ovunque, dai prodotti farmaceutici, inchiostri e vernici ai materiali per la catalisi, le batterie e la fabbricazione del vetro. La misurazione accurata delle nanoparticelle disperse è fondamentale per processi di produzione efficienti e, in ultima analisi, per le prestazioni dei materiali. Il progetto PAT4Nano, finanziato dall’UE, si propone di sviluppare strumenti che consentano la misurazione continua, rapida e affidabile delle nanoparticelle per facilitare la produzione di nanomateriali in modo più efficiente, accurato e meno costoso. Le nuove tecnologie analitiche di processo per la misurazione e l’analisi in linea delle nanoparticelle rilevanti a livello industriale dovrebbero contribuire ad aumentare l’affidabilità e la ripetibilità della produzione di nanoparticelle e potrebbero comportare un risparmio di 3,2 milioni di euro nella produzione farmaceutica.
Obiettivo
PAT4Nano offers an integrated, end user-driven, approach to develop and deploy different, yet complementary particle size measurement technologies for in- and online real-time monitoring. These will quantify particle size distribution and chemical composition in nanosuspensions. With the consortium end user partners (Agfa-Gevaert, Janssen Pharmaceutica, and Johnson Matthey), PAT4Nano will focus on applications in pharmaceuticals, inks/pigments, and materials for catalysis, batteries, and glass manufacture. Continuous, rapid, and reliable real-time data from PAT4Nano tools will provide more comprehensive process information than current offline measurements enabling manufacturers to obtain insights into the fundamental dynamics of nanoparticle-based processes. Furthermore, this information can enable continuous process feedback, opening new opportunities to implement real-time process control and feed-forward loops to correct for process variances, leading to better end product consistency and higher process efficiencies. Multi-PAT solutions, where several complementary measurement methods are combined, together with advanced data processing, will further enhance capability by increasing the information that can be extracted from measurements, extending the application range further. PAT4Nano solutions will improve process control and efficiency, and the quality of nanosuspension products. The increased quantity and quality of the real-time data will enhance the efficiency and quality of nanomaterial production. Increased reliability and repeatability will result in more efficient R&D which can produce savings of €3.2M per nanomaterial pharmaceutical product development, for advanced materials it could bring annual savings of >€3M and help advance sustainability, while for Agfa the PAT4nano tools can facilitate new business opportunities leading to local investments (mostly employment) of ~€15 M within 10 years.
Campo scientifico
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- engineering and technologymaterials engineering
- natural scienceschemical sciencescatalysis
- engineering and technologynanotechnologynano-materials
- natural sciencescomputer and information sciencesdata sciencedata processing
Parole chiave
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-NMBP-TO-IND-2019
Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
2595 DA Den Haag
Paesi Bassi