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Digitalized Clone for Personalized Medicine

Project description

DEENESFRITPL

Virtual patient models for personalised medicine

The ageing population and chronic diseases are pushing up the price of medical care. As a result, the health sector faces the emergence of inequality since some people rely on private insurance while others remain untreated or improperly. Personalised medicine may be one solution. The connection between engineering, medicine and industry could result in quality and productivity improvement. The EU-funded DCPM project proposes the use of model-based methods and advanced identification systems to establish virtual patient models for use in personalised medicine. DCPM will integrate model-based methods in metabolic, cardiovascular and pulmonary systems to create individual virtual intensive care patients to provide personalised medicine applications to actual patients.

Objective

Background: Health consumes ~10% of GDP in the OECD, and grows an unsustainable 7-11% per year, and is ~1% of GDP for intensive care alone, driven by chronic diseases and aging populations. Limited funding leads to an ‘equity gap’ in health funding, where more people go untreated, less treated (rationing), and/or rely on private insurance and care, creating and exacerbating inequality.

Problem: This labor intensive sector has not made productivity gains, and increasing demographic demand for intensive care is multiplied by a growing need for personalized, precision solutions to care.

Challenge: Reverse this trend by linking engineering, medicine, and industry to improve the quality, precision and productivity of intensive care, and create a template for other areas of care.

Objectives: Use model-based methods and novel system identification technologies to create validated virtual patient models for use in personalizing care to enhance its quality and productivity.

Proposed Solution: Tight collaboration between engineering research, clinical medicine, and industry to create, validate, and implement precision, intensive care medicine (DCPM) using in-silico virtual patients. The proposal authors are world-leaders in creating highly validated virtual patients, and translating them to clinical use to provide precision, next-generation productive, intensive care solutions. It will merge model-based methods in metabolic, cardiovascular and pulmonary systems – 3 leading causes of intensive care admission, mortality and cost - to create individual (and then combined) virtual intensive care patients to personalize care at the bedside. The consortia leverages significant research funding in 3rd country partners for model-based medical solutions. This proposed mobility optimizes this research for maximum social and economic impact in the EU and NZ – Doing medicine better via inter-disciplinary, in-silico solutions to productivity in intensive care.

Fields of science

Programme(s)

Topic(s)

Call for proposal

H2020-MSCA-RISE-2019

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Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

BUDAPESTI MUSZAKI ES GAZDASAGTUDOMANYI EGYETEM
Net EU contribution
€ 197 800,00
Address
Muegyetem rakpart 3
1111 Budapest
Hungary

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Region
Közép-Magyarország Budapest Budapest
Activity type
Higher or Secondary Education Establishments
Links
Other funding
€ 27 600,00

Participants (7)

Partners (2)

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Last update: 26 December 2022

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Permalink: https://cordis.europa.eu/project/id/872488

European Union, 2023