Project description
Virtual patient models for personalised medicine
The ageing population and chronic diseases are pushing up the price of medical care. As a result, the health sector faces the emergence of inequality since some people rely on private insurance while others remain untreated or improperly. Personalised medicine may be one solution. The connection between engineering, medicine and industry could result in quality and productivity improvement. The EU-funded DCPM project proposes the use of model-based methods and advanced identification systems to establish virtual patient models for use in personalised medicine. DCPM will integrate model-based methods in metabolic, cardiovascular and pulmonary systems to create individual virtual intensive care patients to provide personalised medicine applications to actual patients.
Objective
Background: Health consumes ~10% of GDP in the OECD, and grows an unsustainable 7-11% per year, and is ~1% of GDP for intensive care alone, driven by chronic diseases and aging populations. Limited funding leads to an ‘equity gap’ in health funding, where more people go untreated, less treated (rationing), and/or rely on private insurance and care, creating and exacerbating inequality.
Problem: This labor intensive sector has not made productivity gains, and increasing demographic demand for intensive care is multiplied by a growing need for personalized, precision solutions to care.
Challenge: Reverse this trend by linking engineering, medicine, and industry to improve the quality, precision and productivity of intensive care, and create a template for other areas of care.
Objectives: Use model-based methods and novel system identification technologies to create validated virtual patient models for use in personalizing care to enhance its quality and productivity.
Proposed Solution: Tight collaboration between engineering research, clinical medicine, and industry to create, validate, and implement precision, intensive care medicine (DCPM) using in-silico virtual patients. The proposal authors are world-leaders in creating highly validated virtual patients, and translating them to clinical use to provide precision, next-generation productive, intensive care solutions. It will merge model-based methods in metabolic, cardiovascular and pulmonary systems – 3 leading causes of intensive care admission, mortality and cost - to create individual (and then combined) virtual intensive care patients to personalize care at the bedside. The consortia leverages significant research funding in 3rd country partners for model-based medical solutions. This proposed mobility optimizes this research for maximum social and economic impact in the EU and NZ – Doing medicine better via inter-disciplinary, in-silico solutions to productivity in intensive care.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- social sciences sociology demography mortality
- social sciences economics and business economics production economics productivity
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-RISE-2019
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1111 Budapest
Hungary
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.