Deliverables
This report will summarize the results of the study of the market in terms of business potential drivers and barriers including externalities
Report on cardiac and vascular microtissue formation capacity of WP3´s materialsMaterials (hydrogels and fibres) generated by WP3 will be tested for their capacity to generate cardiac and vascular microtissues, and the results will inform decision-making at WP3.
Production of hiPSC-derived CMs, stromal/vascular cellsContinuous production of hiPSCderived CMs stromalvascular cells following the SOP will take place to supply the needs of the devised activities
Presentation of the Data Management PlanPreparation and presentation of the Data Management Plan
Data feed for WP2 activitiesData on fibre orientation cardiac function electrophysiology and biomechanics will be obtained from animals undergoing cardiac ischemia This information will feed activities on WP2
Surgery planned, surgeons trainedTransplantation of BioVADs onto infarted pigs will be evaluated and planned.
Stakeholder analysisThis report will include an identification of the most relevant stakeholders within and around the BRAV3 innovations and set up tailored engagement strategies. It will indicate the different Tiers to differentiate the determined stakeholders by modality and timing of their engagement during the project as well as the results of the stakeholder online survey and/or deep-dive interviews.
Design of the official BRAV3 logo and graphical chart to generate visual identity for the project. Also, an official webpage will be created for BRAV3, to inform public and scientific community about different issues related to the project.
An External Advisory Board will be created with the consortium. The EAB will help provide support to the BRAV∃ project, which will be composed of a group of professionals with excellence in: Regenerative Medicine, clinical translation, technological development, ethics, businesses and patient organisation.
Publications
Author(s):
Sampaio-Pinto V, Janssen J, Chirico N, Serra M, Alves PM, Doevendans PA, Voets IK, Sluijter JPG, van Laake LW, van Mil A
Published in:
Adv Mater, Issue 09359648, 2021, ISSN 0935-9648
Publisher:
United Nations Industrial Developement Organization
DOI:
10.1002/adma.202008517
Author(s):
Pilar Montero; María Flandes-Iparraguirre; Saioa Musquiz; Saioa Musquiz; María Pérez Araluce; María Pérez Araluce; Daniel Plano; Daniel Plano; Carmen Sanmartín; Carmen Sanmartín; Gorka Orive; Gorka Orive; Gorka Orive; Gorka Orive; Juan José Gavira; Juan José Gavira; Felipe Prosper; Felipe Prosper; Felipe Prosper; Manuel M. Mazo; Manuel M. Mazo; Manuel M. Mazo
Published in:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020), Issue 22964185, 2020, ISSN 2296-4185
Publisher:
Frontiers Media SA
DOI:
10.3389/fbioe.2020.00955
Author(s):
Chirico N, Van Laake LW, Sluijter JPG, van Mil A, Dierickx P
Published in:
Curr Opin Pharmacol, Issue 14714892, 2021, Page(s) 49-59, ISSN 1471-4892
Publisher:
Elsevier BV
DOI:
10.1016/j.coph.2020.11.006
Author(s):
Pesce M, Agostoni P, Bøtker HE, Brundel B, Davidson SM, De Caterina R, Ferdinandy P, Girao H, Gyöngyösi M, Hulot JS, Lecour S, Perrino C, Schulz R, Sluijter JPG, Steffens S, Tancevski I, Gollmann-Tepeköylü C, Tschöpe C, van Linthout S, Madonna R
Published in:
Cardiovasc Res, Issue 00086363, 2021, ISSN 0008-6363
Publisher:
Elsevier BV
DOI:
10.1093/cvr/cvab201
Author(s):
Tenreiro MF, Almeida HV, Calmeiro T, Fortunato E, Ferreira L, Alves PM, Serra M
Published in:
Scientific Reports, Issue 20452322, 2021, Page(s) 20834, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-021-00226-5
Author(s):
Louro AF, Virgolini N, Paiva MA, Isidro IA, Alves PM, Gomes-Alves P, Serra M
Published in:
Front Physiol, Issue 1664042X, 2022, Page(s) 926528, ISSN 1664-042X
Publisher:
Frontiers Research Foundation
DOI:
10.3389/fphys.2022.926528
Author(s):
Tadevosyan, K. (Karine); Iglesias-García, O. (Olalla); Mazo, M. (Manuel); Prosper, F. (Felipe); Raya, Á. (Ángel)
Published in:
Int J Mol Sci, Issue 14220067, 2021, Page(s) 1479, ISSN 1422-0067
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms22031479
Author(s):
4. Tenreiro M, Louro AF, Alves PM, Serra M
Published in:
NPJ Regen Med, Issue 20573995, 2021, ISSN 2057-3995
Publisher:
NPJ Nature Partner Journals
DOI:
10.1038/s41536-021-00140-4
Author(s):
Sebastião MJ, Serra M, Gomes-Alves P, Alves
Published in:
Current Opinion in Biotechnology, Issue 09581669, 2021, Page(s) 175-181, ISSN 0958-1669
Publisher:
Elsevier BV
DOI:
10.1016/j.copbio.2021.07.021
Author(s):
Ana Maria Sanchez de la Nava; Ana Maria Sanchez de la Nava; Ana Maria Sanchez de la Nava; Ángel Arenal; Ángel Arenal; Ángel Arenal; Francisco Fernández-Avilés; Francisco Fernández-Avilés; Francisco Fernández-Avilés; Felipe Atienza; Felipe Atienza; Felipe Atienza
Published in:
Frontiers in Physiology, Issue 1664042X, 2021, ISSN 1664-042X
Publisher:
Frontiers Research Foundation
DOI:
10.3389/fphys.2021.768468
Author(s):
Bernardo Abecasis; Bernardo Abecasis; Pedro G.M. Canhão; Pedro G.M. Canhão; Henrique V. Almeida; Henrique V. Almeida; Tomás Calmeiro; Elvira Fortunato; Patrícia Gomes-Alves; Patrícia Gomes-Alves; Margarida Serra; Margarida Serra; Paula M. Alves; Paula M. Alves
Published in:
Frontiers in Bioengineering and Biotechnology, Issue 22964185, 2020, ISSN 2296-4185
Publisher:
Frontiers Media S.A.
DOI:
10.3389/fbioe.2020.580744
Author(s):
Henrique V. Almeida; Miguel F. Tenreiro; Ana F. Louro; Bernardo Abecasis; Deolinda Santinha; Tomás Calmeiro; Elvira Fortunato; Lino Ferreira; Paula M. Alves; Margarida Serra
Published in:
ACS Applied Bio Materials, Issue 25766422, 2021, Page(s) 1888-1889, ISSN 2576-6422
Publisher:
ACS Publications
DOI:
10.1021/acsabm.0c01490
Author(s):
Louro AF, Paiva MA, Oliveira MR, Kasper KA, Alves PM, Gomes-Alves P, Serra M
Published in:
Adv Sci, Issue 21983844, 2022, Page(s) e2104296, ISSN 2198-3844
Publisher:
Wiley-VCH
DOI:
10.1002/advs.202104296
Author(s):
Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW
Published in:
STAR Protoc, Issue 26661667, 2021, Page(s) 100334, ISSN 2666-1667
Publisher:
Cell Press
DOI:
10.1016/j.xpro.2021.100334
Author(s):
Sánchez de la Nava AM, Gómez-Cid L, Ríos-Muñoz GR, Fernández-Santos ME, Fernández AI, Arenal A, Sanz-Ruiz R, Grigorian-Shamagian L, Atienza F, Fernández-Avilés F
Published in:
BioTech, Issue 26736284, 2022, Page(s) 23, ISSN 2673-6284
Publisher:
Basel: MDPI AG
DOI:
10.3390/biotech11030023
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