A modular strategy for the repair of critical sized bone fractures

Informations projet

HEALIKICK

N° de convention de subvention: 874889

DOI 10.3030/874889

Date de signature de la CE 4 Mai 2020

Date de début 1 Juin 2020

Date de fin 31 Mai 2025

Financé au titre de

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Coût total € 5 243 535,50

Contribution de l’UE € 5 243 535,50

Coordonné par

UNIVERSITY OF GLASGOW
United Kingdom

Livrables

Demonstrators, pilots, prototypes (3)

Nanovibrational bioreactors to supply WP2.

Nanovibrational bioreactors to supply WP2

In vitro data demonstrating the effect of nanovibration on ovine aMSCs.
In vitro data demonstrating the effect of nanovibration on human aMSCs.

Open Research Data Pilot (1)

A consortium data management plan.

A consortium data management plan

Other (1)

A confirmed clinical team for first human trial of the two technologies.

Publications

Peer reviewed articles (3)

An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration

Auteurs: Juan Antonio Romero-Torrecilla; José María Lamo-Espinosa; Purificación Ripalda-Cemboráin; Tania López-Martínez; Gloria Abizanda; Luis Riera-Álvarez; Sergio Ruiz de Galarreta-Moriones; Asier López-Barberena; Naiara Rodríguez-Flórez; Reyes Elizalde; Vineetha Jayawarna; José Valdés-Fernández; Miguel Echanove-González de Anleo; Peter Childs; Elena de Juan-Pardo; Manuel Salmeron-Sanchez;
Publié dans: NPJ Regenerative Medicine, 2023, ISSN 2057-3995
Éditeur: Springer Nature
DOI: 10.1038/s41536-023-00330-2

An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration

Auteurs: Udesh Dhawan; Hussain Jaffery; Manuel Salmerón-Sánchez; Matthew J. Dalby
Publié dans: Current Opinion in Biotechnology, Numéro 1, 2021, ISSN 0958-1669
Éditeur: Elsevier BV
DOI: 10.1016/j.copbio.2021.10.010

Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

Auteurs: José Valdés‐Fernández, Tania López‐Martínez, Purificación Ripalda‐Cemboráin, Isabel A Calvo, Borja Sáez, Juan Antonio Romero‐Torrecilla, Javier Aldazabal, Emma Muiños‐López, Verónica Montiel, Josune Orbe, José Antonio Rodríguez, José Antonio Páramo, Felipe Prósper, Froilán Granero‐Moltó
Publié dans: Journal of Bone and Mineral Research, Numéro 36/11, 2021, Page(s) 2203-2213, ISSN 0884-0431
Éditeur: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4403