A modular strategy for the repair of critical sized bone fractures

Projektinformationen

HEALIKICK

ID Finanzhilfevereinbarung: 874889

DOI 10.3030/874889

EK-Unterschriftsdatum 4 Mai 2020

Startdatum 1 Juni 2020

Enddatum 31 Mai 2025

Finanziert unter

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Gesamtkosten € 5 243 535,50

EU-Beitrag € 5 243 535,50

Koordiniert durch

UNIVERSITY OF GLASGOW
United Kingdom

Leistungen

Demonstrators, pilots, prototypes (3)

Nanovibrational bioreactors to supply WP2.

Nanovibrational bioreactors to supply WP2

In vitro data demonstrating the effect of nanovibration on ovine aMSCs.
In vitro data demonstrating the effect of nanovibration on human aMSCs.

Open Research Data Pilot (1)

A consortium data management plan.

A consortium data management plan

Other (1)

A confirmed clinical team for first human trial of the two technologies.

Veröffentlichungen

Peer reviewed articles (3)

An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration

Autoren: Juan Antonio Romero-Torrecilla; José María Lamo-Espinosa; Purificación Ripalda-Cemboráin; Tania López-Martínez; Gloria Abizanda; Luis Riera-Álvarez; Sergio Ruiz de Galarreta-Moriones; Asier López-Barberena; Naiara Rodríguez-Flórez; Reyes Elizalde; Vineetha Jayawarna; José Valdés-Fernández; Miguel Echanove-González de Anleo; Peter Childs; Elena de Juan-Pardo; Manuel Salmeron-Sanchez;
Veröffentlicht in: NPJ Regenerative Medicine, 2023, ISSN 2057-3995
Herausgeber: Springer Nature
DOI: 10.1038/s41536-023-00330-2

An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration

Autoren: Udesh Dhawan; Hussain Jaffery; Manuel Salmerón-Sánchez; Matthew J. Dalby
Veröffentlicht in: Current Opinion in Biotechnology, Ausgabe 1, 2021, ISSN 0958-1669
Herausgeber: Elsevier BV
DOI: 10.1016/j.copbio.2021.10.010

Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

Autoren: José Valdés‐Fernández, Tania López‐Martínez, Purificación Ripalda‐Cemboráin, Isabel A Calvo, Borja Sáez, Juan Antonio Romero‐Torrecilla, Javier Aldazabal, Emma Muiños‐López, Verónica Montiel, Josune Orbe, José Antonio Rodríguez, José Antonio Páramo, Felipe Prósper, Froilán Granero‐Moltó
Veröffentlicht in: Journal of Bone and Mineral Research, Ausgabe 36/11, 2021, Seite(n) 2203-2213, ISSN 0884-0431
Herausgeber: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4403