A modular strategy for the repair of critical sized bone fractures

Informacje na temat projektu

HEALIKICK

Identyfikator umowy o grant: 874889

DOI 10.3030/874889

Data podpisania przez KE 4 Maja 2020

Data rozpoczęcia 1 Czerwca 2020

Data zakończenia 31 Maja 2025

Finansowanie w ramach

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Koszt całkowity € 5 243 535,50

Wkład UE € 5 243 535,50

Koordynowany przez

UNIVERSITY OF GLASGOW
United Kingdom

Rezultaty

Demonstrators, pilots, prototypes (3)

Nanovibrational bioreactors to supply WP2.

Nanovibrational bioreactors to supply WP2

In vitro data demonstrating the effect of nanovibration on ovine aMSCs.
In vitro data demonstrating the effect of nanovibration on human aMSCs.

Open Research Data Pilot (1)

A consortium data management plan.

A consortium data management plan

Other (1)

A confirmed clinical team for first human trial of the two technologies.

Publikacje

Peer reviewed articles (3)

An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration

Autorzy: Juan Antonio Romero-Torrecilla; José María Lamo-Espinosa; Purificación Ripalda-Cemboráin; Tania López-Martínez; Gloria Abizanda; Luis Riera-Álvarez; Sergio Ruiz de Galarreta-Moriones; Asier López-Barberena; Naiara Rodríguez-Flórez; Reyes Elizalde; Vineetha Jayawarna; José Valdés-Fernández; Miguel Echanove-González de Anleo; Peter Childs; Elena de Juan-Pardo; Manuel Salmeron-Sanchez;
Opublikowane w: NPJ Regenerative Medicine, 2023, ISSN 2057-3995
Wydawca: Springer Nature
DOI: 10.1038/s41536-023-00330-2

An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration

Autorzy: Udesh Dhawan; Hussain Jaffery; Manuel Salmerón-Sánchez; Matthew J. Dalby
Opublikowane w: Current Opinion in Biotechnology, Numer 1, 2021, ISSN 0958-1669
Wydawca: Elsevier BV
DOI: 10.1016/j.copbio.2021.10.010

Molecular and Cellular Mechanisms of Delayed Fracture Healing in Mmp10 (Stromelysin 2) Knockout Mice

Autorzy: José Valdés‐Fernández, Tania López‐Martínez, Purificación Ripalda‐Cemboráin, Isabel A Calvo, Borja Sáez, Juan Antonio Romero‐Torrecilla, Javier Aldazabal, Emma Muiños‐López, Verónica Montiel, Josune Orbe, José Antonio Rodríguez, José Antonio Páramo, Felipe Prósper, Froilán Granero‐Moltó
Opublikowane w: Journal of Bone and Mineral Research, Numer 36/11, 2021, Strona(/y) 2203-2213, ISSN 0884-0431
Wydawca: American Society for Bone and Mineral Research
DOI: 10.1002/jbmr.4403