Project description
Multiple sclerosis immune cell characterisation to provide new disease biomarker
Currently, there is no biomarker for monitoring the progression of the chronic inflammatory disease multiple sclerosis (MS). To address this, scientists of the EU-funded IMPACT project will investigate the immune compartment of patients at a single cell level using machine learning approaches. They will also eliminate the impact of an individual's genetic makeup on disease signature by studying a unique cohort of monozygotic twin pairs. Results will help unveil disease-specific signals and undertake a more precise characterisation of immune cell populations implicated in MS pathology. Ultimately, the study will lead to the identification of biomarkers that could be routinely used in the clinic.
Fields of science
- natural sciencesbiological sciencesneurobiology
- medical and health scienceshealth sciencesinflammatory diseases
- medical and health sciencesbasic medicineneurologymultiple sclerosis
- medical and health sciencesbasic medicineimmunology
- medical and health sciencesmedical biotechnologycells technologiesstem cells
Programme(s)
Topic(s)
Funding Scheme
ERC-ADG - Advanced Grant
Host institution
8006 Zurich
Switzerland
See on map
Beneficiaries (1)
8006 Zurich
See on map