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The human retina at single cell resolution: functional architecture, disease mechanism and therapy development

Project description

Single cell resolution study on the human retina to restore vision after disease

Vision commences in the retina, where photoreceptors capture an image and then transmit the information to the brain through the retina circuitry. Most blinding eye diseases emerge from dysfunction in the retina, necessitating delineation of its architecture in health and disease. Using recently developed technologies, the EU-funded HURET project aims to study the human retina in terms of functional diversity and determine the different cell types that compose its neural circuitry. Scientists will identify mechanisms of cell-type vulnerability that cause disease, paving the way for novel interventions for restoring vision in patients with blinding eye diseases.

Call for proposal

ERC-2019-ADG
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Funding Scheme

ERC-ADG - Advanced Grant

Host institution

INSTITUT FUR MOLEKULARE UND KLINISCHE OPHTHALMOLOGIE BASEL
Address
C/o Universitätsspital Basel, Augenklinik, Mittlere Strasse
4056 Basel
Switzerland
Activity type
Research Organisations
EU contribution
€ 2 500 000

Beneficiaries (1)

INSTITUT FUR MOLEKULARE UND KLINISCHE OPHTHALMOLOGIE BASEL
Switzerland
EU contribution
€ 2 500 000
Address
C/o Universitätsspital Basel, Augenklinik, Mittlere Strasse
4056 Basel
Activity type
Research Organisations