PERSONALISATION OF IMMUNOSUPPRESSION BY MONITORING VIRAL LOAD POST KIDNEY TRANSPLANTATION - A RANDOMISED CONTROLLED PHASE II TRIAL

Project Information

TTV GUIDE TX

Grant agreement ID: 896932

DOI 10.3030/896932

EC signature date 2 February 2021

Start date 1 May 2021

End date 30 April 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 6 099 831,00

EU contribution € 6 099 831,00

Coordinated by

MEDIZINISCHE UNIVERSITAET WIEN
Austria

Deliverables

Documents, reports (4)

M30 Review Report

Public report on activities of the project

Ethics and Governance framework
Conclusions from the Kick-off
M18 Review report

Public report on activities of the project

Websites, patent fillings, videos etc. (1)

TTV GUIDE TX public website

Publications

Peer reviewed articles (7)

Integrated Immunologic Monitoring in Solid Organ Transplantation: The Road Toward Torque Teno Virus-guided Immunosuppression.

Author(s): Jaksch P, Görzer I, Puchhammer-Stöckl E, Bond G.
Published in: Transplantation, 2022, ISSN 0041-1337
Publisher: Lippincott Williams & Wilkins Ltd.

Torque teno virus viral load predicts SARS-CoV-2 vaccine response in kidney transplant recipients

Author(s): Morgane Solis, Ilies Benotmane, Floriane Gallais, Sophie Caillard, Samira Fafi-Kremer
Published in: Journal of Medical Virology, 2023, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1002/jmv.28936

Torque Teno Viral Plasma Load for Immunologic Monitoring in Solid Organ Transplantation: One Step Further

Author(s): Frederik Haupenthal, Gregor Bond
Published in: Transplantation, 2023, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.1097/tp.0000000000004817

TTV and other anelloviruses: The astonishingly wide spread of a viral infection

Author(s): Pietro Giorgio Spezia, Daniele Focosi, Andreina Baj, Federica Novazzi, Francesca Drago Ferrante, Fabrizio Carletti, Claudia Minosse, Giulia Matusali, Fabrizio Maggi
Published in: Aspects of Molecular Medicine, 2023, ISSN 2949-6888
Publisher: Elsevier
DOI: 10.1016/j.amolm.2023.100006

Validation of plasma Torque Teno viral load applying a CE-certified PCR for risk stratification of rejection and infection post kidney transplantation

Author(s): Irene Görzer; Frederik Haupenthal; Fabrizio Maggi; Fanny Gelas; Dorian Kulifaj; Ludovic Brossault; Elisabeth Puchhammer-Stöckl; Gregor Bond
Published in: Journal of Clinical Virology, 2023, ISSN 1873-5967
Publisher: Elsevier
DOI: 10.1016/j.jcv.2022.105348

High-Density Lipoprotein Particles and Torque Teno Virus in Stable Outpatient Kidney Transplant Recipients

Author(s): Jip Jonker, Caecilia S. E. Doorenbos, Daan Kremer, Edmund J. Gore, Hubert G. M. Niesters, Coretta van Leer-Buter, Philippe Bourgeois, Margery A. Connelly, Robin P. F. Dullaart, Stefan P. Berger, Jan-Stephan F. Sanders and Stephan J. L. Bakker
Published in: Viruses, 2023, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v16010143

A multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and torque teno virus-guided immunosuppressionin kidney transplant recipients in the first year after transplantation: TTVguideIT

Author(s): Frederik Haupenthal1, Jette Rahn2, Fabrizio Maggi3, Fanny Gelas4, Philippe Bourgeois4, Christian Hugo5, Bernd Jilma6, Georg A. Böhmig1, Harald Herkner7, Michael Wolzt8, Konstantin Doberer1, Matthias Vossen9, Daniele Focosi10, Hannes Neuwirt11, Miriam Banas12, Bernhard Banas12, Klemens Budde13, Ondrej Viklicky14, Paolo Malvezzi15, Lionel Rostaing15, Joris I. Rotmans16, Stephan J. L. Bakker17, Kath
Published in: BMC, 2023, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.1186/s13063-023-07216-0