Neural Active Visual Prosthetics for Restoring Function

Deliverables

Report & pipeline for self-calibrating stimulation

This report describes the opensource software which will be used for MLbased phosphene vision Opensource software will be disseminated via a publicly accessible repository

Report on flexible shaft electrodes

Report the longterm stability stimulation efficacy and biocompatibility of flexible probes during in vivo applications in the visual cortex of rodents The analysis is based on monitoring tissue gliosis impedance stability and twophoton calcium imaging to access neural activity

Network simulation study

Report of study of the initial AI networks of WP4 targeting the hardware FPGA implementations and the impact of reduced bit precision of weights and activations

Report on self-calibrating neural stimulation

This report describes adaptive algorithms that automatically determine optimal stimulation parameters to induce each phosphene The openaccess report will be submitted to a conference or journal for academic dissemination

Data management plan

Description of the data management plan for the collected data during the project

Project website

Report on project website which will also be used to update the public on the NeuraViPeR project

Publications

An In-Silico Framework for Modeling Optimal Control of Neural Systems

Author(s): Rueckauer, B. and van Gerven, M.
Published in: Frontiers in Neuroscience, Issue Continuous, 2023, ISSN 1662-4548
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnins.2023.1141884

Optimization of Neuroprosthetic Vision via End-to-End Deep Reinforcement Learning

Author(s): Küçükoğlu, B., Rueckauer, B., Ahmad, N., van Steveninck, J. R., Güçlü, U., and van Gerven, M.
Published in: International Journal of Neural Systems, Issue Quarterly, 2022, ISSN 0129-0657
Publisher: World Scientific Publishing Co
DOI: 10.1142/s0129065722500526

Solving the binding problem: assemblies form when neurons enhance their firing rate – they don’t need to oscillate or synchronize

Author(s): Roelfsema, P.R
Published in: Neuron, Issue Monthly, 2023, ISSN 0896-6273
Publisher: Cell Press
DOI: 10.1016/j.neuron.2023.03.016

1024-channel electrophysiological recordings in macaque V1 and V4 during resting state

Author(s): Chen X*, Morales-Gregorio A*, Sridhar S, Sprenger J, van Albada SJ, Grün S, Roelfsema PR.
Published in: Scientific Data, Issue continuous, 2022, ISSN 2052-4463
Publisher: Springer Nature
DOI: 10.1038/s41597-022-01180-1

Toward a personalized closed-loop stimulation of the visual cortex: Advances and challenges

Author(s): Grani, F., Soto-Sánchez, C., Fimia, A., & Fernández, E.
Published in: Frontiers in Cellular Neuroscience, Issue Continuous, 2022, ISSN 1662-5102
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncel.2022.1034270

Multilayer Arrays for Neurotechnology Applications (MANTA): Chronically Stable Thin-Film Intracortical Implants

Author(s): C. Boehler, M. Vomero, M. Soula, M. Vöröslakos, M. Porto Cruz, R. Liljemalm, G. Buzsaki, T. Stieglitz, M. Asplund
Published in: Advanced Science, Issue Monthly, 2023, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202207576

Time stability and connectivity analysis with an intracortical 96-channel microelectrode array inserted in human visual cortex

Author(s): Grani, F., Soto-Sánchez, C., Farfan, F. D., Alfaro, A., Grima, M. D., Doblado, A. R., & Fernández, E
Published in: Journal of Neural Engineering, Issue Quarterly, 2022, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac801d

Chronic stability of a neuroprosthesis comprising multiple adjacent Utah arrays in monkeys

Author(s): X. Chen, F: Wang, R. Kooijmans, P.C. Klink, C. Boehler, M. Asplund, P.R. Roelfsema
Published in: Journal of Neural Engineering, Issue Quarterly, 2023, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ace07e

Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex

Author(s): Fernandez, E., Alfaro, A., Soto-Sanchez, C., Gonzalez-Lopez, P., Lozano, A., Peña, S., Rodil, A., Gomez, B., Chez, X., Roefsema, P., Rolston, J., Davis, T., Normann, RA.
Published in: Journal of Clinical Investigation, Issue continuous, 2021, ISSN 0021-9738
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci151331

Engineering strategies towards overcoming bleeding and glial scar formation around neural probes

Author(s): Otte E, Vlachos A, Asplund M
Published in: Cell and Tissue Research, Issue 4, 2022, ISSN 0302-766X
Publisher: Springer Verlag
DOI: 10.1007/s00441-021-03567-9

Biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses

Author(s): van der Grinten, M. L., de Ruyter van Steveninck, J., Lozano, A., Pijnacker, L., Rueckauer, B., Roelfsema, P., van Gerven, M., van Wezel, R., Güçlü, U., Güçlütürk, Y.
Published in: bioRxiv, Issue continuous, 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Labs
DOI: 10.1101/2022.12.23.521749

New Wafer-Level Fabrication of Ultrathin Silicon Insertion Shuttles for Flexible Neural Implants

Author(s): K. Sharma, C. Boehler, M. Asplund, O. Paul, and P. Ruther
Published in: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS), Issue Annually, 2023
Publisher: IEEE
DOI: 10.1109/mems49605.2023.10052581

Experiencing prosthetic vision with event-based sensors

Author(s): Rückauer, B.J.; Gerven, M.A.J. van; Potok, T.E.; Schuman, C.
Published in: Proceedings of the International Conference on Neuromorphic Systems, Issue Annually, 2022
Publisher: Association for Computing Machinery (ACM)
DOI: 10.1145/3546790.3546813

Lightweight semantic segmentation networks for real-time visual prosthesis applications

Author(s): H. Wang, H. Mohamed, Z. Wang, B. Rueckauer, S-C. Liu
Published in: 2021 ICCV Workshop (The 1st Workshop on Video Scene Parsing in the Wild), Issue 1, 2021, ISSN 2473-9944
Publisher: IEEE Computer Society
DOI: 10.1109/iccvw54120.2021.00300

Fast temporal decoding from large-scale neural recordings in monkey visual cortex

Author(s): Hadorn, J.*, Wang, Z.*, Rueckauer, B., Chen, X., Roelfsema, P., Liu, S.-C
Published in: NeurIPS 2022 Workshop on Shared Visual Representations in Human & Machine Intelligence, Issue Annually, 2022
Publisher: NeurIPS
DOI: 10.3929/ethz-b-000595073

Hierarchical Bonding Yield Test Structure for Flexible High Channel-Count Neural Probes Interfacing ASIC Chips

Author(s): M. C. Odenthal, V. Claar, O. Paul, and P. Ruther
Published in: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS), Issue Annually, 2023
Publisher: IEEE
DOI: 10.1109/mems49605.2023.10052500

Deliverables

Publications

Share this page

Download