Neural Active Visual Prosthetics for Restoring Function

Rezultaty

Report & pipeline for self-calibrating stimulation

This report describes the opensource software which will be used for MLbased phosphene vision Opensource software will be disseminated via a publicly accessible repository

Report on flexible shaft electrodes

Report the longterm stability stimulation efficacy and biocompatibility of flexible probes during in vivo applications in the visual cortex of rodents The analysis is based on monitoring tissue gliosis impedance stability and twophoton calcium imaging to access neural activity

Network simulation study

Report of study of the initial AI networks of WP4 targeting the hardware FPGA implementations and the impact of reduced bit precision of weights and activations

Report on self-calibrating neural stimulation

This report describes adaptive algorithms that automatically determine optimal stimulation parameters to induce each phosphene The openaccess report will be submitted to a conference or journal for academic dissemination

Data management plan

Description of the data management plan for the collected data during the project

Project website

Report on project website which will also be used to update the public on the NeuraViPeR project

Complementary metal oxide semiconductor interconnected and stackable (up to 4) multi-shaft 128 channel probes

Flexible probes interconnected with stackable interface, encapsulated and ready for implantation.

Publikacje

An In-Silico Framework for Modeling Optimal Control of Neural Systems

Autorzy: Rueckauer, B. and van Gerven, M.
Opublikowane w: Frontiers in Neuroscience, Numer Continuous, 2023, ISSN 1662-4548
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnins.2023.1141884

Optimization of Neuroprosthetic Vision via End-to-End Deep Reinforcement Learning

Autorzy: Küçükoğlu, B., Rueckauer, B., Ahmad, N., van Steveninck, J. R., Güçlü, U., and van Gerven, M.
Opublikowane w: International Journal of Neural Systems, Numer Quarterly, 2022, ISSN 0129-0657
Wydawca: World Scientific Publishing Co
DOI: 10.1142/s0129065722500526

Solving the binding problem: assemblies form when neurons enhance their firing rate – they don’t need to oscillate or synchronize

Autorzy: Roelfsema, P.R
Opublikowane w: Neuron, Numer Monthly, 2023, ISSN 0896-6273
Wydawca: Cell Press
DOI: 10.1016/j.neuron.2023.03.016

1024-channel electrophysiological recordings in macaque V1 and V4 during resting state

Autorzy: Chen X*, Morales-Gregorio A*, Sridhar S, Sprenger J, van Albada SJ, Grün S, Roelfsema PR.
Opublikowane w: Scientific Data, Numer continuous, 2022, ISSN 2052-4463
Wydawca: Springer Nature
DOI: 10.1038/s41597-022-01180-1

Toward a personalized closed-loop stimulation of the visual cortex: Advances and challenges

Autorzy: Grani, F., Soto-Sánchez, C., Fimia, A., & Fernández, E.
Opublikowane w: Frontiers in Cellular Neuroscience, Numer Continuous, 2022, ISSN 1662-5102
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fncel.2022.1034270

Multilayer Arrays for Neurotechnology Applications (MANTA): Chronically Stable Thin-Film Intracortical Implants

Autorzy: C. Boehler, M. Vomero, M. Soula, M. Vöröslakos, M. Porto Cruz, R. Liljemalm, G. Buzsaki, T. Stieglitz, M. Asplund
Opublikowane w: Advanced Science, Numer Monthly, 2023, ISSN 2198-3844
Wydawca: Wiley
DOI: 10.1002/advs.202207576

Time stability and connectivity analysis with an intracortical 96-channel microelectrode array inserted in human visual cortex

Autorzy: Grani, F., Soto-Sánchez, C., Farfan, F. D., Alfaro, A., Grima, M. D., Doblado, A. R., & Fernández, E
Opublikowane w: Journal of Neural Engineering, Numer Quarterly, 2022, ISSN 1741-2560
Wydawca: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac801d

Chronic stability of a neuroprosthesis comprising multiple adjacent Utah arrays in monkeys

Autorzy: X. Chen, F: Wang, R. Kooijmans, P.C. Klink, C. Boehler, M. Asplund, P.R. Roelfsema
Opublikowane w: Journal of Neural Engineering, Numer Quarterly, 2023, ISSN 1741-2560
Wydawca: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ace07e

Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex

Autorzy: Fernandez, E., Alfaro, A., Soto-Sanchez, C., Gonzalez-Lopez, P., Lozano, A., Peña, S., Rodil, A., Gomez, B., Chez, X., Roefsema, P., Rolston, J., Davis, T., Normann, RA.
Opublikowane w: Journal of Clinical Investigation, Numer continuous, 2021, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci151331

Engineering strategies towards overcoming bleeding and glial scar formation around neural probes

Autorzy: Otte E, Vlachos A, Asplund M
Opublikowane w: Cell and Tissue Research, Numer 4, 2022, ISSN 0302-766X
Wydawca: Springer Verlag
DOI: 10.1007/s00441-021-03567-9

Biologically plausible phosphene simulation for the differentiable optimization of visual cortical prostheses

Autorzy: van der Grinten, M. L., de Ruyter van Steveninck, J., Lozano, A., Pijnacker, L., Rueckauer, B., Roelfsema, P., van Gerven, M., van Wezel, R., Güçlü, U., Güçlütürk, Y.
Opublikowane w: bioRxiv, Numer continuous, 2022, ISSN 2692-8205
Wydawca: Cold Spring Harbor Labs
DOI: 10.1101/2022.12.23.521749

New Wafer-Level Fabrication of Ultrathin Silicon Insertion Shuttles for Flexible Neural Implants

Autorzy: K. Sharma, C. Boehler, M. Asplund, O. Paul, and P. Ruther
Opublikowane w: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS), Numer Annually, 2023
Wydawca: IEEE
DOI: 10.1109/mems49605.2023.10052581

Experiencing prosthetic vision with event-based sensors

Autorzy: Rückauer, B.J.; Gerven, M.A.J. van; Potok, T.E.; Schuman, C.
Opublikowane w: Proceedings of the International Conference on Neuromorphic Systems, Numer Annually, 2022
Wydawca: Association for Computing Machinery (ACM)
DOI: 10.1145/3546790.3546813

Lightweight semantic segmentation networks for real-time visual prosthesis applications

Autorzy: H. Wang, H. Mohamed, Z. Wang, B. Rueckauer, S-C. Liu
Opublikowane w: 2021 ICCV Workshop (The 1st Workshop on Video Scene Parsing in the Wild), Numer 1, 2021, ISSN 2473-9944
Wydawca: IEEE Computer Society
DOI: 10.1109/iccvw54120.2021.00300

Fast temporal decoding from large-scale neural recordings in monkey visual cortex

Autorzy: Hadorn, J.*, Wang, Z.*, Rueckauer, B., Chen, X., Roelfsema, P., Liu, S.-C
Opublikowane w: NeurIPS 2022 Workshop on Shared Visual Representations in Human & Machine Intelligence, Numer Annually, 2022
Wydawca: NeurIPS
DOI: 10.3929/ethz-b-000595073

Hierarchical Bonding Yield Test Structure for Flexible High Channel-Count Neural Probes Interfacing ASIC Chips

Autorzy: M. C. Odenthal, V. Claar, O. Paul, and P. Ruther
Opublikowane w: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS), Numer Annually, 2023
Wydawca: IEEE
DOI: 10.1109/mems49605.2023.10052500

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