Descrizione del progetto
Indagare sui sistemi di materia condensata nel contesto di più scale temporali
Le funzioni di quasi tutti gli oggetti concepiti e prodotti si basano sulle proprietà delle singole molecole e della materia condensata. La comprensione e il miglioramento delle proprietà della materia condensata richiedono la determinazione sia della struttura che della dinamica, con una risoluzione atomica su una gamma molto vasta di scale temporali. Il progetto HIRES-MULTIDYN, finanziato dall’UE, introdurrà una tecnologia rivoluzionaria, chiamata rilassometria ad alta risoluzione ultrarapida (UHRR, Ultrafast High-Resolution Relaxometry), per determinare le dinamiche di sistemi complessi in scale temporali che vanno dai picosecondi ai microsecondi. I ricercatori costruiranno e testeranno prototipi sottoposti a prove di fattibilità degli strumenti UHRR. Svilupperanno anche un quadro teorico per comprendere le rivoluzionarie misurazioni ottenute dalla UHRR e le interpreteranno in termini di movimenti molecolari. I prototipi UHRR potrebbero trovare applicazione in una vasta gamma di ambiti, come la progettazione di farmaci, gli alimenti, la salute e l’energia.
Obiettivo
The properties of individual molecules and condensed matter are at the origin of the functions of almost every single product conceived, produced or analysed. Understanding and improving the properties of condensed matter requires the determination of both structure and dynamics with atomic resolution over a very broad range of timescales. No technique is available today to determine dynamics from picoseconds up to microseconds of complex systems in liquids with atomic resolution. The HIRES-MULTIDYN project introduces a ground-breaking technology: ultrafast high-resolution relaxometry (UHRR), which synergizes the high-resolution power of high-field nuclear magnetic resonance with multiscale dynamics low-field relaxation based on a new concept for critical fast-field switching. We will design, build, and test the first two proof-of-concept prototypes of UHRR instruments. We will develop the theoretical framework to understand the unprecedented measurements obtained by UHRR and interpret them in terms of molecular motions. We will exploit UHRR prototypes in a series of proof-of-concept applications covering a broad range of fields (drug design, food and health sciences, energy). These applications will demonstrate the unprecedented analytical power of UHRR and generate the momentum required to lead to the future development of a commercial UHRR system built in Europe. The HIRES-MULTIDYN project brings together a tight and complementary consortium of engineers, experimental scientists and theoreticians who are world leaders in NMR methods development, instrumentation, applications and in the theoretical foundations of magnetic relaxation and molecular dynamics simulations. Our ambition is to develop UHRR as a novel technology to determine the dynamic properties of condensed matter that will, within the next decade, boost the ability of scientists to innovate in academia and several industries (from pharma to food, energy and beyond) and enhance public health.
Campo scientifico
Parole chiave
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-FETOPEN-2018-2019-2020-01
Meccanismo di finanziamento
RIA - Research and Innovation actionCoordinatore
75230 Paris
Francia