Ultrasound peripheral interface and in-vitro model of human somatosensory system and muscles for motor decoding and restoration of somatic sensations in amputees

Información del proyecto

SOMA

Identificador del acuerdo de subvención: 899822

DOI

10.3030/899822

Proyecto cerrado

Fecha de la firma de la CE 26 Mayo 2020

Fecha de inicio 1 Septiembre 2020

Fecha de finalización 28 Febrero 2025

Financiado con arreglo a

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coste total

€ 2 999 998,75

Aportación de la UE

€ 2 999 998,75

Coordinado por

UNIVERSITA CAMPUS BIO MEDICO DI ROMA
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Websites, patent fillings, videos etc. (1)

Project website and communication channels

Open Research Data Pilot (1)

Data Management Plan (DMP)

Report on Data Management Plan

Documents, reports (2)

Report on in-vivo US stimulation and recording
Functional and histological results of biocompatibility and safety

Report on functional and histological results of biocompatibility and safety

Publicaciones

Peer reviewed articles (26)

Kinematics of individual muscle units in natural contractions measured in vivo using ultrafast ultrasound

Autores: Emma Lubel; Bruno Grandi Sgambato; Deren Y Barsakcioglu; Jaime Ibáñez; Meng-Xing Tang; Dario Farina
Publicado en: Journal of Neural Engineering, 2022, ISSN 1741-2560
Editor: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac8c6c

Method for Automatic Slippage Detection With Tactile Sensors Embedded in Prosthetic Hands

Autores: Rocco A. Romeo, Clemente Lauretti, Cosimo Gentile, Eugenio Guglielmelli, Loredana Zollo
Publicado en: IEEE Transactions on Medical Robotics and Bionics, Edición 3/2, 2021, Página(s) 485-497, ISSN 2576-3202
Editor: IEEE
DOI: 10.1109/tmrb.2021.3060032

Restoring somatotopic sensory feedback in lower limb amputees through non-invasive nerve stimulation

Autores: Andrea Demofonti, Marco Germanotta, Andrea Zingaro, Gaia Bailo, Sabina Insalaco, Francesca Cordella, Irene Giovanna Aprile, Loredana Zollo
Publicado en: Cyborg and Bionic Systems, 2025, ISSN 2692-7632
Editor: Science Partner Journals
DOI: 10.34133/cbsystems.0243

Repair of long peripheral nerve defects in sheep: a translational model for nerve regeneration

Autores: Contreras E, Traserra S, Bolívar S, Forés J, Jose-Cunilleras E, Delgado-Martínez I, García F, Udina E, Navarro X.
Publicado en: International Journal of Molecular Science, 2023, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24021333

Hierarchical strategy for sEMG classification of the hand/wrist gestures and forces of transradial amputees

Autores: Francesca Leone, Federico Mereu, Cosimo Gentile, Francesca Cordella, Emanuele Gruppioni, Loredana Zollo
Publicado en: Frontiers in Neurorobotics, Edición 17, 2023, ISSN 1662-5218
Editor: Frontiers Research Foundation
DOI: 10.3389/fnbot.2023.1092006

A High-Voltage Differential SPDT T/R Switch for Ultrasound Systems

Autores: Yaohua Zhang, Dai Jiang, Andreas Demosthenous
Publicado en: IEEE Transactions on Circuits and Systems I: Regular Papers, Edición 71, 2024, Página(s) 5129-5140, ISSN 1549-8328
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tcsi.2024.3426558

Mechanical and thermal stimulation for studying the somatosensory system: a review on devices and methods

Autores: M Sperduti, N L Tagliamonte, F Taffoni, E Guglielmelli, L Zollo
Publicado en: Journal of Neural Engineering, Edición 21, 2024, Página(s) 051001, ISSN 1741-2560
Editor: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ad716d

Validation of Magneto-Inertial Measurement Units for Upper-Limb Motion Analysis Through an Anthropomorphic Robot

Autores: M. Lapresa, C. Tamantini, F. Scotto di Luzio, M. Ferlazzo, G. Sorrenti, F. Corpina, L. Zollo
Publicado en: IEEE Sensors Journal, 2022, ISSN 1530-437X
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jsen.2022.3193313

A multiscale approach to axon and nerve stimulation modeling: A review

Autores: Mattia STEFANO, Francesca Cordella, Alessandro Loppini, Simonetta Filippi, Loredana Zollo
Publicado en: IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2021, ISSN 1534-4320
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tnsre.2021.3054551

Eliciting Force and Slippage in Upper Limb Amputees Through Transcutaneous Electrical Nerve Stimulation (TENS)

Autores: A. Scarpelli, A. Demofonti, F. Cordella, U. Coffa, F. Mereu, E. Gruppioni, L. Zollo
Publicado en: IEEE Transactions on Neural Systems and Rehabilitation Engineering, Edición 32, 2024, Página(s) 3006-3017, ISSN 1534-4320
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tnsre.2024.3443398

Performance Assessment of Thermal Sensors for Hand Prostheses

Autores: Enrica Stefanelli, Marika Sperduti, Francesca Cordella, Nevio Luigi Tagliamonte, Loredana Zollo
Publicado en: IEEE Sensors Journal, Edición 24, 2024, Página(s) 27559-27569, ISSN 1530-437X
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jsen.2024.3431274

Accurate Identification of Motoneuron Discharges From Ultrasound Images Across the Full Muscle Cross-Section

Autores: Emma Lubel, Robin Rohlén, Bruno Grandi Sgambato, Deren Y Barsakcioglu, Jaime Ibáñez, Meng-Xing Tang, Dario Farina
Publicado en: IEEE Transactions on Biomedical Engineering, Edición 71, 2024, Página(s) 1466-1477, ISSN 0018-9294
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2023.3340019

Assessment of focused ultrasound stimulation to induce peripheral nerve activity and potential damage in vivo

Autores: Bruno Rodríguez-Meana, Eva Santos-Nogueira, Sònia Trujillo-Vázquez, Anette Jakob, Esther Udina, Marc Fournelle, Xavier Navarro
Publicado en: Frontiers in Neurology, Edición 15, 2024, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2024.1346412

Assessing the impact of degree of fusion and muscle fibre twitch shape variation on the accuracy of motor unit discharge time identification from ultrasound images

Autores: Robin Rohlén, Emma Lubel, Dario Farina
Publicado en: Biomedical Signal Processing and Control, Edición 100, 2025, Página(s) 107002, ISSN 1746-8094
Editor: Elsevier BV
DOI: 10.1016/j.bspc.2024.107002

Study of Electrical Neural Stimulation Effects Using Extraneural and Intraneural Electrodes

Autores: Mattia Stefano, Francesca Cordella, Giulia Cozza, Anna Lisa Ciancio, Loredana Zollo
Publicado en: Applied Sciences, Edición 13, 2023, Página(s) 6267, ISSN 2076-3417
Editor: MDPI
DOI: 10.3390/app13106267

Hand Prosthesis Sensorimotor Control Inspired by the Human Somatosensory System

Autores: Enrica Stefanelli, Francesca Cordella, Cosimo Gentile, Loredana Zollo
Publicado en: Robotics, Edición 12, 2025, Página(s) 136, ISSN 2218-6581
Editor: MDPI
DOI: 10.3390/robotics12050136

High Performance Wearable Ultrasound as a Human-Machine Interface for Wrist and Hand Kinematic Tracking

Autores: Bruno Grandi Sgambato, Milia H Hasbani, Deren Y Barsakcioglu, Jaime Ibáñez, Anette Jakob, Marc Fournelle, Meng-Xing Tang, Dario Farina
Publicado en: IEEE Transactions on Biomedical Engineering, Edición 71, 2024, Página(s) 484-493, ISSN 0018-9294
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2023.3307952

Integrated Circuits for Medical Ultrasound Applications: Imaging and Beyond

Autores: Yaohua Zhang; Andreas Demosthenous
Publicado en: IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS, 2021, ISSN 1932-4545
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbcas.2021.3120886

Control Strategies and Performance Assessment of Upper-Limb TMR Prostheses: A Review

Autores: F. Mereu, F. Leone, C. Gentile, F. Cordella, E. Gruppioni, L. Zollo
Publicado en: Sensors, 2021, ISSN 1424-8220
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21061953

Design of a modular and compliant wrist module for upper limb prosthetics

Autores: A. Demofonti, G. Carpino, N. L. Tagliamonte, G. Baldini, L. Bramato, L. Zollo
Publicado en: The Anatomical Record, 2022, ISSN 1932-8494
Editor: John Wiley and Co.
DOI: 10.1002/ar.24911

Spatial decomposition of ultrafast ultrasound images to identify motor unit activity – A comparative study with intramuscular and surface EMG

Autores: Robin Rohlén, Emma Lubel, Bruno Grandi Sgambato, Christian Antfolk, Dario Farina
Publicado en: Journal of Electromyography and Kinesiology, Edición 73, 2023, Página(s) 102825, ISSN 1050-6411
Editor: Elsevier BV
DOI: 10.1016/j.jelekin.2023.102825

Evaluation of the effects of focused ultrasound stimulation on the central nervous system through a multiscale simulation approach

Autores: A. Scarpelli, M. Stefano, F. Cordella, L. Zollo
Publicado en: Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
Editor: Frontiers
DOI: 10.3389/fbioe.2022.1034194

Hierarchical Human-Inspired Control Strategies for Prosthetic Hands

Autores: Cosimo Gentile, Francesca Cordella, Loredana Zollo
Publicado en: Sensors, Edición 22, 2024, Página(s) 2521, ISSN 1424-8220
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s22072521

Analysis of Hand Intra-Finger Couplings During Flexion Movements in the Free Space

Autores: Martina Lapresa, Alessandro Ceccarelli, Fabrizio Taffoni, Nevio Luigi Tagliamonte, Loredana Zollo, Francesca Cordella
Publicado en: IEEE Access, Edición 11, 2023, Página(s) 90084-90093, ISSN 2169-3536
Editor: Institute of Electrical and Electronics Engineers Inc.
DOI: 10.1109/access.2023.3307417

Non-linearity in motor unit velocity twitch dynamics: Implications for ultrafast ultrasound source separation

Autores: Emma Lubel, Bruno Grandi Sgambato, Robin Rohlén, Jaime Ibáñez, Deren Y Barsakcioglu, Meng-Xing Tang, Dario Farina
Publicado en: EEE TRANSACTIONS ON NEURAL SYSTEMS ANDREHABILITATION ENGINEERING, 2023, ISSN 1534-4320
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1101/2023.03.24.533983

A parallel classification strategy to simultaneous control elbow, wrist, and hand movements

Autores: Francesca Leone; Cosimo Gentile; Francesca Cordella; Emanuele Gruppioni; Eugenio Guglielmelli; Loredana Zollo
Publicado en: Journal of NeuroEngineering and Rehabilitation, 2022, ISSN 1743-0003
Editor: BioMed Central
DOI: 10.1186/s12984-022-00982-z

Conference proceedings (2)

Electrical stimulation of the human median nerve: A comparison between anatomical and simplified simulation models

Autores: Mattia Stefano, Francesca Cordella, Salvatore Maria Li Gioi, Loredana Zollo
Publicado en: 2021 10th International IEEE/EMBS Conference on Neural Engineering (NER), 2021, Página(s) 769-772, ISBN 978-1-7281-4337-8
Editor: IEEE
DOI: 10.1109/ner49283.2021.9441187

Modulation of sensation intensity in the lower limb via Transcutaneous Electrical Nerve Stimulation

Autores: Demofonti A., Scarpelli A., Cordella F. and Zollo L.
Publicado en: 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2021
Editor: IEEE

Book chapters (1)

Neural electrodes for long-term tissue interfaces. In Guçlu B (ed): “

Autores: del Valle J, Rodríguez-Meana B, Navarro X
Publicado en: Somatosensory Feedback for Neuroprosthetics, Edición Single, 2021, Página(s) 509-536, ISBN 978-0-12-822828-9
Editor: Elsevier