Advanced High Aspect Ratio and Multicomponent materials: towards comprehensive intelLigent tEsting and Safe by design Strategies

Leistungen

Bioaccumulation and persistency evaluation of selected NMs

Report describing the bioaccumulation at the entry-point of the trophic chain, according to the data obtained for algae and daphnia, and the possibilities of biomagnification according to the data obtained for fish. Since persistency of the NMs plays a key role in bioaccumulation by determining the availability of NMs for organisms, the report will incorporate the results of the persistency studies.

Overview of relevant AOPs to inform NAM choice of KEs

Report summarizing relevant AOPs and selection of candidate Key Events and Adverse Outcomes suitable forNAM in WP3

Open access repository of mRNA single cell response

Open access repository of mRNA single cell response profiles detected in lung tissue flowing pulmonary exposure. Report on the comparison of lung single cell response profiles of (intubated ventilated) inhalation and instillation exposed rodents.

HARMLESS database with extensions to handle advanced materials

The report will include description of HARMLESS-eNanoMapper database setup, content and ontology annotations, and the implemented approach of advanced materials representation.

Veröffentlichungen

Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro

Autoren: Doryab, A., Heydarian, M., Yildirim, A.Ö., Hilgendorff, A., Behr, J., Schmid, O.,
Veröffentlicht in: Journal of Drug Delivery Science and Technology, Ausgabe 85, 2023, Seite(n) still ePub, ISSN 1773-2247
Herausgeber: Editions de Sante
DOI: 10.1016/j.jddst.2023.104316

evaluating use and performance

Autoren: Krans, N A; Ammar, A; Nymark, P; Willighagen, E L; Bakker, M I; Quik, J T K
Veröffentlicht in: NanoImpact, Ausgabe 24520748, 2022, ISSN 2452-0748
Herausgeber: Elservier BV
DOI: 10.1016/j.impact.2022.100402

Towards Computer-Aided Graphene Covered TiO2-Cu/(CuxOy) Composite Design for the Purpose of Photoinduced Hydrogen Evolution

Autoren: Łukasz Lewandowski; Agnieszka Gajewicz-Skretna; Tomasz Klimczuk; Grzegorz Trykowski; Kostiantyn Nikiforow; Wojciech Lisowski; Anna Gołąbiewska; Adriana Zaleska-Medynska
Veröffentlicht in: Catalysts Ausgabe 6, Ausgabe 2, 2021, ISSN 2073-4344
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/catal11060698

Single-walled vs. Multi-walled Carbon Nanotubes: Influence of Physico-Chemical Properties on Toxicogenomics Responses of Mouse Lungs

Autoren: Silvia A. Solorio-Rodriguez, Andrew Williams, Sarah Søs Poulsen, Kristina B. Knudsen, Keld Alstrup Jensen, Per A. Clausen, Pernille Høgh Danielsen, Håkan Wallin, Ulla Vogel, Sabina Halappanavar
Veröffentlicht in: "NanoMaterials - Special Ausgabe ""Safety and Toxicity of Carbon Nanotubes""", Ausgabe 13, 2023, Seite(n) 1059, ISSN 2079-4991
Herausgeber: MDPI
DOI: 10.3390/nano13061059

Meta‐Analysis of Integrated Proteomic and Transcriptomic Data Discerns Structure–Activity Relationship of Carbon Materials with Different Morphologies

Autoren: Verónica I. Dumit; Yuk‐Chien Liu; Aileen Bahl; Pekka Kohonen; Roland C. Grafström; Penny Nymark; Christine Müller‐Graf; Andrea Haase; Mario Pink
Veröffentlicht in: Advanced Science, Ausgabe 2, 2023, ISSN 1613-6829
Herausgeber: Wiley Online Library
DOI: 10.1002/advs.202306268

Referee report. For: ELIXIR and Toxicology: a community in development [version 1; peer review: 1 approved, 1 approved with reservations]

Autoren: Eide, Marta
Veröffentlicht in: ELIXIR, Ausgabe 3, 2023, ISSN 2229-712X
Herausgeber: F1000 Research
DOI: 10.5256/f1000research.78265.r124031

Editorial: Exploring impacts of combined exposures to particles and chemicals on immune reactions across living organisms

Autoren: Diana Boraschi, Albert Duschl, Iseult Lynch and Tobias Stoeger
Veröffentlicht in: Frontiers in Toxicology, Ausgabe 5, 2023, Seite(n) still ePub, ISSN 2673-3080
Herausgeber: Frontiers in Toxicology
DOI: 10.3389/ftox.2023.1148374

An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials

Autoren: Bannuscher, A., Schmid, O., et al. Doryab, A., et al. Clift, M.J.D., Rothen-Rutishauser, B.
Veröffentlicht in: NanoImpact, Ausgabe 28, 2022, Seite(n) 100439, ISSN 2452-0748
Herausgeber: ScienceDirect
DOI: 10.1016/j.impact.2022.100439

ELIXIR and Toxicology: a community in development

Autoren: Marvin Martens; Rob Stierum; Emma L. Schymanski; Chris T. Evelo; Reza Aalizadeh; Hristo Aladjov; Kasia Arturi; Karine Audouze; Pavel Babica; Karel Berka; Jos Bessems; Ludek Blaha; Evan E Bolton; Montserrat Cases; Dimitrios Damalas; Kirtan Dave; Marco Dilger; Thomas Exner; Daan P. Geerke; Roland C. Grafström; Alasdair J. G. Gray; John M. Hancock; Henner Hollert; Nina Jeliazkova; Danyel Jennen; Fab
Veröffentlicht in: ELIXIR and Toxicology: a community in development, Ausgabe 20461402, 2021, ISSN 2046-1402
Herausgeber: F1000 Research Ltd.
DOI: 10.12688/f1000research.74502.1

Behaviour of advanced materials in environmental aquatic media – dissolution kinetics and dispersion stability of perovskite automotive catalysts

Autoren: Veronica Di Battista; Kai Werle; Lars Michael Skjolding; Wendel Wohlleben; Anders Baun
Veröffentlicht in: Environmental science: Nano, on the special issue on Advanced Materials, Ausgabe 2, 2023, ISSN 2754-7000
Herausgeber: RSC - The Royal Society of Chemistry
DOI: 10.1039/d3en00685a

Status, implications and challenges of European safe and sustainable by design paradigms applicable to nanomaterials and advanced materials

Autoren: Irini Furxhi, Anna Costa, Socorro Vázquez-Campos, Carlos Fito-López, Danail Hristozov, Juan Antonio Tamayo Ramos, Susanne Resch, Margherita Cioffi, Steffi Friedrichs, Cris Rocca, Eugenia Valsami-Jones, Iseult Lynch, Sánchez Jiménez Aracelil, Lucian Farcal
Veröffentlicht in: RSC Sustainability, 2023, ISSN 2753-8125
Herausgeber: The Royal Society of Chemistry
DOI: 10.1039/d2su00101b

Transferability and reproducibility of exposed air-liquid interface co-culture lung models

Autoren: Hedwig M, Braakhuis; Eric R, Gremmer; Anne, Bannuscher; Barbara, Drasler; Sandeep, Keshavan; Barbara, Rothen-Rutishauser; Barbara, Birk; Andreas, Verlohner; Robert, Landsiedel; Kirsty, Meldrum; Shareen H, Doak; Martin J D, Clift; Johanna Samulin, Erdem; Oda A H, Foss; Shanbeh, Zienolddiny-Narui; Tommaso, Serchi; Elisa, Moschini; Pamina, Weber; Sabina, Burla; Pramod, Kumar; Otmar, Schmid; Edwin, Zw
Veröffentlicht in: NanoImpact, Ausgabe 4, 2023, ISSN 2452-0748
Herausgeber: ScienceDirect
DOI: 10.1016/j.impact.2023.100466

Effect of Exposure Concentration and Growth Conditions on the Association of Cerium Oxide Nanoparticles with Green Algae

Autoren: Aiga Mackevica; Lyndsey Hendriks; Olga Meili-Borovinskaya; Anders Baun; Lars Michael Skjolding
Veröffentlicht in: Nanomaterials , vol. 13 , no. 17, Ausgabe 2, 2023, ISSN 2079-4991
Herausgeber: MDPI
DOI: 10.3390/nano13172468

Release of particulate matter from nano-enabled building materials (NEBMs) across their lifecycle: Potential occupational health and safety implications

Autoren: Dilpreet Singh, Antonella Marrocco, Wendel Wohlleben, Hae-Ryung Park, Avantika R. Diwadkar, Blanca E. Himes, Quan Lu, David C. Christiani, Philip Demokritou
Veröffentlicht in: Journal of Hazarous Materials, Ausgabe 03043894, 2022, ISSN 0304-3894
Herausgeber: Elsevier BV
DOI: 10.1016/j.jhazmat.2021.126771

Prospective environmental risk screening of seven advanced materials based on production volumes and aquatic ecotoxicity

Autoren: Rickard Arvidsson; Gregory Peters; Steffen Foss Hansen; Anders Baun
Veröffentlicht in: NanoImpact, Ausgabe 24520748, 2022, ISSN 2452-0748
Herausgeber: Elsevier BV
DOI: 10.1016/j.impact.2022.100393

A novel quantitative read-across tool designed purposefully to fill the existing gaps in nanosafety data

Autoren: Mainak Chatterjee; Arkaprava Banerjee; Priyanka De; Agnieszka Gajewicz-Skretna; Kunal Roy
Veröffentlicht in: Environmental Science: Nano, Ausgabe 1, 2021, ISSN 2051-8153
Herausgeber: Royal Society of Chemistry
DOI: 10.1039/d1en00725d

highlights from the Basic and Translational Science Assembly

Autoren: Sara Cuevas Ocaña; Natalia El-Merhie; Merian E. Kuipers; Mareike Lehmann; Sara Rolandsson Enes; Carola Voss; Lareb S.N. Dean; Matthew Loxham; Agnes W. Boots; Suzanne M. Cloonan; Catherine M. Greene; Irene H. Heijink; Audrey Joannes; Arnaud A. Mailleux; Nahal Mansouri; Niki L. Reynaert; Anne M. van der Does; Darcy E. Wagner; Niki Ubags
Veröffentlicht in: Erj Open Research, Ausgabe 2, 2023, ISSN 2312-0541
Herausgeber: European Respiratory Society
DOI: 10.1183/23120541.00561-2022

Lung Organoids for Hazard Assessment of Nanomaterials

Autoren: Miriam T. Kastlmeier; Eva M. Guenther; Tobias Stoeger; Carola Voss
Veröffentlicht in: Int. J. Mol. Sci. 23:15666 (2022), Ausgabe 4, 2022, ISSN 1422-0067
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms232415666

INISS-Nano: revised concept and action plan (International Network Initiative on Safe and Sustainable Nanotechnologies)

Autoren: Andreas Falk; Pogany, Alexander; Aungkavattana, Pavadee; Bañares, Miguel A.; Beitollahi, Ali; Bim, Vinicius; Briffa, Sophie; Bochon, Anthony; Cassee, Flemming; Doridot, Fernand; Exner, Thomas; Farias, Patricia M.A.; Favre, Georges; Franzese, Giancarlo; Friedrichs, Steffi; Hristozov, Danail; Hunt, Neil; Indaraprasirt, Ramjitti; Karim, Md. E.; Khandelwal, Neha; Malsch, Ineke; Marcoulaki, Effie; Mar
Veröffentlicht in: INISS-nano, 2022
Herausgeber: Concept Paper
DOI: 10.5281/zenodo.6818049

International Network Initiative on Safe and Sustainable Nanotechnologies (INISS-nano)

Autoren: Falk, Andreas
Veröffentlicht in: INISS-nano, 2021
Herausgeber: Concept Paper
DOI: 10.5281/zenodo.5004929

Engineered nanomaterial-relevant AOPs; network creation and identification of key nodes for adverse outcomes

Autoren: Pousen, Sarah Søs; Baun, Anders; Stöger, Tobias; Navas, José María; Connolly, Mona; Vogel, Ulla B.
Veröffentlicht in: Ausgabe 1, 2022
Herausgeber: “Nano-week” & NanoCommons Final Conference
DOI: 10.5281/zenodo.6806067

AOP training session

Autoren: Vogel, Ulla; Poulsen, Sarah Søs
Veröffentlicht in: 2022
Herausgeber: NanoWeek 2022 and NanoCommons Final Conference
DOI: 10.5281/zenodo.6806125

Conceptual Design of the HARMLESS Decision Support System

Autoren: van Someren, Eugene; Shandilya, Neeraj; Franken, Remy; Krone, Tanja; van Stokkum, Robin; Suarez-Merino, Blanca; Adam, Véronique; Salieri, Beatrice; Wohlleben, Wendel; Kalkman, Gino; van Barneveld, Mark; Tolios, Ioannis; Rubingh, Carina; Krishnan, Shaji; Fransman, Wouter; Dekkers, Susan
Veröffentlicht in: Ausgabe 2, 2022
Herausgeber: “Nano-week” & NanoCommons Final Conference
DOI: 10.5281/zenodo.6806190

Reply to: Prospects and challenges for FAIR toxicogenomics data

Autoren: Roland Grafström; Andrea Haase; Pekka Kohonen; Nina Jeliazkova; Penny Nymark
Veröffentlicht in: Nature Nanotechnology, Ausgabe 17483387, 2022, Seite(n) 19-20, ISSN 1748-3387
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41565-021-01050-8

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