A fully integrated, animal-free, end-to-end modelling approach to oral drug product development

Información del proyecto

InPharma

Identificador del acuerdo de subvención: 955756

DOI 10.3030/955756

Fecha de la firma de la CE 7 Septiembre 2020

Fecha de inicio 1 Enero 2021

Fecha de finalización 31 Diciembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total € 3 464 964,00

Aportación de la UE € 3 464 964,00

Coordinado por

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

Resultado final

Documents, reports (2)

Public Engagement & Dissemination (PED) Plan published

Public Engagement Dissemination PED Plan published

Gap analysis on in vitro methods for enabling formulations

Websites, patent fillings, videos etc. (3)

InPharma Science Slam videos published on website
Ask Me Anything (AMA) InPharma

Ask Me Anything AMA InPharma

InPharma website established

Publicaciones

Peer reviewed articles (5)

Exploring the Cocrystal Landscape of Posaconazole by Combining High-Throughput Screening Experimentation with Computational Chemistry

Autores: Matteo Guidetti, Rolf Hilfiker, Martin Kuentz, Annette Bauer-Brandl, Fritz Blatter
Publicado en: Crystal Growth & Design, Edición 23, 2, 2022, Página(s) 842-852, ISSN 1528-7483
Editor: American Chemical Society
DOI: 10.1021/acs.cgd.2c01072

Polymer-embedded deep eutectic solvents (PEDES) as a novel bio-enabling formulation approach

Autores: Shaida Panbachi , Josef Beranek, Martin Kuentz
Publicado en: European Journal of Pharmaceutical Sciences, Edición Volume 186, 1 July 2023, 2023, ISSN 0928-0987
Editor: Elsevier BV
DOI: 10.1016/j.ejps.2023.106463

Projection of Target Drug Particle Size in Oral Formulations Using the Refined Developability Classification System (rDCS)

Autores: Kristian Beran; Eline Hermans; René Holm; Kia Sepassi; Jennifer Dressman
Publicado en: Pharmaceutics; Volume 15; Edición 7; Pages: 1909, Edición 1, 2023, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15071909

Microdialysis and nanofiltration allow to distinguish molecularly dissolved from colloid-associated drug concentrations during biomimetic dissolution testing of supersaturating formulations

Autores: Florentin Lukas Holzem, Jeannine Petrig Schaffland, Martin Brandl, Annette Bauer-Brandl, Cordula Stillhart
Publicado en: European Journal of Pharmaceutical Sciences, Edición Volume 174, 1 July 2022, 2022, ISSN 0928-0987
Editor: Elsevier BV
DOI: 10.1016/j.ejps.2022.106166

Biopredictive capability assessment of two dissolution/permeation assays, µFLUXTM and PermeaLoopTM, using supersaturating formulations of Posaconazole

Autores: Florentin Lukas Holzem, Anika Weck, Jeannine Petrig Schaffland, Cordula Stillhart, Sandra Klein, Annette Bauer-Brandl, Martin Brandl
Publicado en: European Journal of Pharmaceutical Sciences, Edición 176, 2022, Página(s) 106260, ISSN 0928-0987
Editor: Elsevier BV
DOI: 10.1016/j.ejps.2022.106260