A fully integrated, animal-free, end-to-end modelling approach to oral drug product development

Informazioni relative al progetto

InPharma

ID dell’accordo di sovvenzione: 955756

DOI 10.3030/955756

Data della firma CE 7 Settembre 2020

Data di avvio 1 Gennaio 2021

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale € 3 464 964,00

Contributo UE € 3 464 964,00

Coordinato da

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

Risultati finali

Documents, reports (2)

Public Engagement & Dissemination (PED) Plan published

Public Engagement Dissemination PED Plan published

Gap analysis on in vitro methods for enabling formulations

Websites, patent fillings, videos etc. (3)

InPharma Science Slam videos published on website
Ask Me Anything (AMA) InPharma

Ask Me Anything AMA InPharma

InPharma website established

Pubblicazioni

Peer reviewed articles (5)

Exploring the Cocrystal Landscape of Posaconazole by Combining High-Throughput Screening Experimentation with Computational Chemistry

Autori: Matteo Guidetti, Rolf Hilfiker, Martin Kuentz, Annette Bauer-Brandl, Fritz Blatter
Pubblicato in: Crystal Growth & Design, Numero 23, 2, 2022, Pagina/e 842-852, ISSN 1528-7483
Editore: American Chemical Society
DOI: 10.1021/acs.cgd.2c01072

Polymer-embedded deep eutectic solvents (PEDES) as a novel bio-enabling formulation approach

Autori: Shaida Panbachi , Josef Beranek, Martin Kuentz
Pubblicato in: European Journal of Pharmaceutical Sciences, Numero Volume 186, 1 July 2023, 2023, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2023.106463

Projection of Target Drug Particle Size in Oral Formulations Using the Refined Developability Classification System (rDCS)

Autori: Kristian Beran; Eline Hermans; René Holm; Kia Sepassi; Jennifer Dressman
Pubblicato in: Pharmaceutics; Volume 15; Numero 7; Pages: 1909, Numero 1, 2023, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15071909

Microdialysis and nanofiltration allow to distinguish molecularly dissolved from colloid-associated drug concentrations during biomimetic dissolution testing of supersaturating formulations

Autori: Florentin Lukas Holzem, Jeannine Petrig Schaffland, Martin Brandl, Annette Bauer-Brandl, Cordula Stillhart
Pubblicato in: European Journal of Pharmaceutical Sciences, Numero Volume 174, 1 July 2022, 2022, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2022.106166

Biopredictive capability assessment of two dissolution/permeation assays, µFLUXTM and PermeaLoopTM, using supersaturating formulations of Posaconazole

Autori: Florentin Lukas Holzem, Anika Weck, Jeannine Petrig Schaffland, Cordula Stillhart, Sandra Klein, Annette Bauer-Brandl, Martin Brandl
Pubblicato in: European Journal of Pharmaceutical Sciences, Numero 176, 2022, Pagina/e 106260, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2022.106260