Objective
Lactic Acid Bacteria (LAB) are industrially important in a range of food, drink and feed industries indigenous to Europe and in addition, their positive roles in human and animal health are receiving increased attention. The G-Project on LAB is organized as a single integrated project that combines the expertise of 36 participating laboratories. The Project is divided into sub-groups to facilitate a targeted focus on key objectives. The sub-groups are: gene regulation; bacteriophage (phage) and phage resistance; bacteriocins; LAB in beer and vaccines.
The project has made impressive progress since its initiation in December 1994. It is clear that the knowledge base and analytical techniques have become sufficiently advanced to address questions regarding the expression of key technologically important traits of LAB. Thus, not only has the organisation of the genetic loci for a range of significant traits such as bacteriophage resistance (abortive infection, restriction/modification), bacteriocin production and immunity, and amino acid biosynthesis been elucidated but the complex networks by which these activities are regulated are also being unravelled. The work on bacteriophages of LAB is yielding relevant information on phage/host interactions which is a key element in generating strategies for combating phage infection in commercial practice. The fundamental and applied research on bacteriocins has highlighted features regarding induction of bacteriocin activity, the role of media constituents in affecting activity spectrum and the successful application of some bacteriocins in food trials. Potentially new taxa of beer spoilage LAB have been identified and detection methods are being refined and made more sensitive. A significant advance has been the demonstration of the feasibility of using LAB as presentation hosts for foreign antigens in order to induce a host immune response. These advances stem from an excellent integration of the disciplines of Microbiology, Molecular Biology and Immunology.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry organic acids
- natural sciences biological sciences microbiology virology
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- natural sciences chemical sciences organic chemistry amines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
30 Cork
Ireland
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Participants (27)
1432 Aas
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24103 Kiel
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31062 Toulouse
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41012 SEVILLA
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MK43 0AL Cranfield - Bedford
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2800 Lyngby
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2380 BB ZOETERWOUDE
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9052 GENT
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78352 Jouy-en-Josas
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75475 Paris
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NR4 7UA Norwich
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2301 CE LEIDEN
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6710 EDE GLD
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85748 Garching bei München
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67082 Strasbourg
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53100 SIENA
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1348 LOUVAIN-LA-NEUVE
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9750 AA HAREN GN
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28040 Madrid
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33006 Oviedo
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9000 Gent
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CB2 1QP Cambridge
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90571 Oulu
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29100 Piacenza
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70599 Stuttgart - Hohenheim
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67663 Kaiserslautern
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1050 BRUXELLES
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