Obiettivo The use of nitrofuran antibiotics in farm animals was banned in the EU because of their toxicity. Monitoring compliance with the ban by testing for residues of the parent drugs is ineffective, because they are rapidly metabolised in vivo, and their residues are unstable. Nitrofuran metabolism is complex, with extensive formation of stable, tissue-bound residues with relatively long tissue half lives. Mild acids (like the human stomach) release potentially toxic compounds from bound nitrofuran residues. This project will develop screening tests and a Reference Method for these compounds, to provide an effective tool f or surveillance and enforcement. Methods will be extensively validated according to current EU guidelines; will be used to measure the prevalence of the bound residues in a pan-European survey and to define the length of time for which illegal abuse can be detected. A project web site, a Consumer Awareness Forum, National Reference Laboratory Technology Transfer events and articles prepared for the consumer press will ensure maximum dissemination of the aims and findings of the work to end users; and an SME will develop novel, marketable products. Campo scientifico engineering and technologymedical engineeringmedical laboratory technologymedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-1. - Key action Food, Nutrition and Health Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore THE QUEEN'S UNIVERSITY OF BELFAST Contributo UE Nessun dato Indirizzo Stoney Road , Stormont BT4 3SD BELFAST Regno Unito Mostra sulla mappa Costo totale Nessun dato Partecipanti (5) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto ASSOCIATION DES CONSOMMATEURS TEST- ACHATS Belgio Contributo UE Nessun dato Indirizzo Hollandstraat 13 1060 BRUXELLES Mostra sulla mappa Costo totale Nessun dato NATIONAL FOOD INVESTIGATION INSTITUTE Ungheria Contributo UE Nessun dato Indirizzo Mester Utca 81 1465 BUDAPEST Mostra sulla mappa Costo totale Nessun dato R- BIOPHARM GMBH Germania Contributo UE Nessun dato Indirizzo Dolivostrasse 10 64293 DARMSTADT Mostra sulla mappa Costo totale Nessun dato TEAGASC - AGRICULTURE AND FOOD DEVELOPMENT AUTHORITY Irlanda Contributo UE Nessun dato Indirizzo 19,Dunsinea, Castleknock 15 DUBLIN Mostra sulla mappa Costo totale Nessun dato VETERINARY RESEARCH INSTITUTE Cechia Contributo UE Nessun dato Indirizzo 70,Hudcova 70 621 32 BRNO Mostra sulla mappa Costo totale Nessun dato