Obiettivo
The breast cancer (BC) risk of women with germ line mutations of Becalm or 2 or other high entrance genes is dramatically increased especially at young ages .Dietary and other modifiable life-style factors, however, may influence the early occurrence of BC in mutation carriers. Fruit and vegetable, vitamin E , say products and low glycaemia index food, as well as a low index of abdominal obesity , have been suggested to confer greater protection against hereditary Bethany against sporadic BC. Mechanistic explanations include hormonal effects of diet and antioxidant protection in women with impaired DNA repair. This CASE-ONLYSTUDY aims at testing exposure in patients with and without genetic predisposition, as established through family history or genetic testing. The study base will comprise over 5, 000 patients who got BC before the age of 40 .
Campo scientifico
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturefruit growing
- medical and health sciencesclinical medicineoncologybreast cancer
- natural sciencesbiological sciencesgeneticsmutation
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturevegetable growing
- medical and health scienceshealth sciencesnutritionobesity
Argomento(i)
Invito a presentare proposte
Data not availableMeccanismo di finanziamento
CSC - Cost-sharing contractsCoordinatore
20133 MILANO
Italia