Case-only study on the interaction of diet and genetic predisposition in the occurrence of breast cancer in young women.

Cel

The breast cancer (BC) risk of women with germ line mutations of Becalm or 2 or other high entrance genes is dramatically increased especially at young ages .Dietary and other modifiable life-style factors, however, may influence the early occurrence of BC in mutation carriers. Fruit and vegetable, vitamin E , say products and low glycaemia index food, as well as a low index of abdominal obesity , have been suggested to confer greater protection against hereditary Bethany against sporadic BC. Mechanistic explanations include hormonal effects of diet and antioxidant protection in women with impaired DNA repair. This CASE-ONLYSTUDY aims at testing exposure in patients with and without genetic predisposition, as established through family history or genetic testing. The study base will comprise over 5, 000 patients who got BC before the age of 40 .

Dziedzina nauki

• nauki rolnicze › rolnictwo, leśnictwo i rybołówstwo › rolnictwo › ogrodnictwo › sadownictwo
• medycyna i nauki o zdrowiu › medycyna kliniczna › onkologia › rak piersi
• nauki przyrodnicze › nauki biologiczne › genetyka › mutacja
• nauki rolnicze › rolnictwo, leśnictwo i rybołówstwo › rolnictwo › ogrodnictwo › uprawa warzyw
• medycyna i nauki o zdrowiu › nauki o zdrowiu › odżywianie › otyłość

Program(-y)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Temat(-y)

• 1.1.1.-1. - Key action Food, Nutrition and Health

Zaproszenie do składania wniosków

Data not available

System finansowania

CSC - Cost-sharing contracts

Leaflet | Map data © OpenStreetMap contributors, Credit: EC-GISCO, © EuroGeographics for the administrative boundaries

Koordynator

ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI

Adres

Via Venezian 1
20133 Milano
Włochy

Linki

Uczestnicy (8)

CHAIM SHEBA MEDICAL CENTER

Izrael

Adres

Chair Sheba Medical Center
52621 Tel Hashomer

Linki

ESTONIAN INSTITUTE OF EXPERIMENTAL AND CLINICAL MEDICINE

Estonia

Adres

Hiiu 42
0016 Tallinn

Linki

GERMAN CANCER RESEARCH CENTER

Niemcy

Adres

Im Neuenheimer Feld 280
69120 Heidelberg

Linki

INSTITUTE OF ONCOLOGY LJUBLJANA

Słowenia

Adres

Zaloska 2
1000 Ljubljana

Linki

LEGA ITALIANA PER LA LOTTA CONTRO I TUMORI - ONLUS

Włochy

Adres

Via Dante 109
97100 Ragusa

Linki

UNIVERSITE LOUIS PASTEUR, STRASBOURG 1

Francja

Adres

Rue Kirschleger 4
67085 Strasbourg

Linki

UNIVERSITY OF ABERDEEN

United Kingdom

Adres

Polwarth Building, Foresterhill
AB25 2ZD Aberdeen

Linki

UNIVERSITY OF ST ANDREWS

United Kingdom

Adres

Queen's Terrace, Bute Medical Buildings
KY16 9TS St Andrews

Linki