Obiettivo
Human immunodeficiency viruses resistant to one or more HIV drugs are spreading throughout the world. If further spread of resistant HIV will not be controlled, a future situation may occur, in which no effective HIV drugs will be available for newly infected patients. The size of this problem in Europe is currently unknown, but it is estimated that approximately one fifth of all new infections are due to drug resistant viruses. No systematic information is collected and no strategy is available to prevent further spread of resistant viruses. Within the SPREAD-project clinicians, virologists and epidemiologists from 16 European countries will develop a strategy to control transmission of resistant HIV. They will collect data to reliably determine the incidence of transmission within the different risk groups and to identify risk factors enhancing the risk of transmission. Viruses from 4000 newly diagnosed individuals will be collected between 2001 and 2004 and characterised on mutational and phenotypic level by a network of quality controlled national reference laboratories. The data will be analysed using models and will be used to identify risk groups and predict future trends. Based on these analyses a European strategy will be developed and implemented in collaboration with public health authorities, the clinical community, pharmaceutical industry and patient...
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CSC - Cost-sharing contractsCoordinatore
3584 CX UTRECHT
Paesi Bassi
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Partecipanti (17)
1210 LUXEMBOURG
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08916 BADALONA
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16121 KAISARIANI / ATHENS
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1349-019 LISBOA
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W6 8LH LONDON
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141 86 HUDDINGE
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3000 LOUVAIN / LEUVEN
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00300 HELSINKI
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4 DUBLIN
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0403 OSLO
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HP16 0JS GREAT MISSENDEN/PRESTWOOD
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2300 KOEPENHAGEN
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20157 MILANO
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91054 ERLANGEN
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1095 WIEN
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3581 CP UTRECHT
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01 201 WARSZAWA
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