Obiettivo This project aims to support the hazard and risk assessment of asbestos substitute fibres. The potential for induction of inflammatory changes, oxidative stress, immunotoxicity and genotoxicity will be eximined for three substitute fibres (glass fibres, rock wool, wollastonite) and compared to that of amosite asbestos. Novel cell culture or whole animal systems will be employed to obtained information on the molecular mechanisms and the dose-response relationships governing the induction of the above toxic effects for use in human population studies. These biomarkers of exposure and early effects for use in human population studies. These biomarkers will be applied, together with already existing biomarkers, in biomonitoring studies of cohorts of fibre workers. Campo scientifico engineering and technologymaterials engineering Programma(i) FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002 Argomento(i) 1.1.1.-4. - Key action Environment and Health Invito a presentare proposte Data not available Meccanismo di finanziamento CSC - Cost-sharing contracts Coordinatore NATIONAL HELLENIC RESEARCH FOUNDATION Contributo UE Nessun dato Indirizzo Vassileos Constantinou Avenue 48 ATHENS Grecia Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato Partecipanti (6) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto FODOR JOZSEF NATIONAL PUBLIC HEALTH CENTRE Ungheria Contributo UE Nessun dato Indirizzo Nagyvarad Ter 2 1450 BUDAPEST Mostra sulla mappa Costo totale Nessun dato GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH Germania Contributo UE Nessun dato Indirizzo Ingolstaedter Landstrasse 1 85764 NEUHERBERG Mostra sulla mappa Costo totale Nessun dato INSTITUTE OF MOLECULAR BIOLOGY - BULGARIAN ACADEMY OF SCIENCES Bulgaria Contributo UE Nessun dato Indirizzo 21,Bld Acad. Bonchev 21 1113 SOFIA Mostra sulla mappa Costo totale Nessun dato INSTITUTE OF PREVENTIVE AND CLINICAL MEDICINE Slovacchia Contributo UE Nessun dato Indirizzo 14,Limbova 14 833 01 BRATISLAVA Mostra sulla mappa Costo totale Nessun dato PURKYNJE MILITARY MEDICAL ACADEMY Cechia Contributo UE Nessun dato Indirizzo Trebesska 1575 500 01 HRADEC KRALOVE Mostra sulla mappa Costo totale Nessun dato THE ROBERT GORDON UNIVERSITY Regno Unito Contributo UE Nessun dato Indirizzo Schoolhill ABERDEEN Mostra sulla mappa Collegamenti Sito web Opens in new window Costo totale Nessun dato