Obiettivo There is a need for greater understanding of integrated cellular physiology to exploit cells and to tailor their activities to optimise microbial productivity in synthetic circuits and to limit microbial activity in food and pharmaceutical products. Understanding the integration of the cellular metabolic processes is fundamental to developing and exploiting cells. We have assembled a team of internationally renowned academic and industrial partners to form a training network comprising experimentalists and modellers. The partners will work synergistically to generate a cohort of well-trained young scientists with multidisciplinary skills to drive this research field forward and provide novel tools for academic and industrial research.Our focus in this training programme is a thorough understanding of cytoplasmic homeostasis, because this is integral to the functioning of individual components and whole pathways. Cytoplasmic homeostasis is amenable to both experimentation and modelling and has profound implications for the core processes of life and productivity.The research objectives are:• To advance our understanding of the homeostatic mechanisms of bacteria via predictive modelling and state-of-the-art experimental approaches.• To generate deep insights into effects of perturbation of homeostasis on the core properties of the cell: transcription, translation, metabolism and control over protein activity.• To develop novel approaches to gauge the properties of individual cells and to model the behaviour of single cells, cell collectives in biofilms and multicellular structures.• To develop new chemical and biophysical tools for the analysis of cells and protein complexes in order to understand cellular sub-structure assembly.• To map the location and dynamics of supramolecular assemblies in the cytoplasm and cell membranes.• To manipulate the productivity of the cell and engineer new, tailored activities in the cell for industrial needs. Campo scientifico natural sciencesbiological sciencesmicrobiologybacteriologynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencescell biologysocial scienceseconomics and businesseconomicsproduction economicsproductivitymedical and health sciencesbasic medicinephysiologyhomeostasis Programma(i) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Argomento(i) FP7-PEOPLE-2011-ITN - Marie-Curie Action: "Initial Training Networks" Invito a presentare proposte FP7-PEOPLE-2011-ITN Vedi altri progetti per questo bando Meccanismo di finanziamento MC-ITN - Networks for Initial Training (ITN) Coordinatore RIJKSUNIVERSITEIT GRONINGEN Contributo UE € 731 125,46 Indirizzo Broerstraat 5 9712CP Groningen Paesi Bassi Mostra sulla mappa Regione Noord-Nederland Groningen Overig Groningen Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Jan Poutsma (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato Partecipanti (7) Classifica in ordine alfabetico Classifica per Contributo UE Espandi tutto Riduci tutto UNIVERSITAET POTSDAM Germania Contributo UE € 523 652,79 Indirizzo AM NEUEN PALAIS 10 14469 Potsdam Mostra sulla mappa Regione Brandenburg Brandenburg Potsdam Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Regina Gerber (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN Regno Unito Contributo UE € 854 001,50 Indirizzo KING'S COLLEGE REGENT WALK AB24 3FX ABERDEEN Mostra sulla mappa Regione Scotland North Eastern Scotland Aberdeen City and Aberdeenshire Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Kerry Kidd (Ms.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV Germania Contributo UE € 226 626,40 Indirizzo HOFGARTENSTRASSE 8 80539 Munchen Mostra sulla mappa Regione Bayern Oberbayern München, Kreisfreie Stadt Tipo di attività Research Organisations Contatto amministrativo Reinhard Lipowsky (Prof.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spagna Contributo UE € 456 409,80 Indirizzo CALLE SERRANO 117 28006 Madrid Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Contatto amministrativo Eusebio Jimenez Arroyo (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Regno Unito Contributo UE € 228 388,60 Indirizzo WELLINGTON SQUARE UNIVERSITY OFFICES OX1 2JD Oxford Mostra sulla mappa Regione South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire Tipo di attività Higher or Secondary Education Establishments Contatto amministrativo Stephen Conway (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato DSM FOOD SPECIALTIES BV Paesi Bassi Contributo UE € 211 850,10 Indirizzo ALEXANDER FLEMINGLAAN 1 2613 AX Delft Mostra sulla mappa Regione West-Nederland Zuid-Holland Delft en Westland Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo Roel Bovenberg (Mr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato ASTRAZENECA UK LIMITED Regno Unito Contributo UE € 261 200,51 Indirizzo 1 FRANCIS CRICK AVENUE CAMBRIDGE BIOMEDICAL CAMPUS CB2 0AA Cambridge Mostra sulla mappa Regione East of England East Anglia Cambridgeshire CC Tipo di attività Private for-profit entities (excluding Higher or Secondary Education Establishments) Contatto amministrativo James Yates (Dr.) Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Costo totale Nessun dato