Cel Antimicrobial agents, such as antibiotics, have dramatically reduced the number of deaths from infectious diseases over the last 70 years. However, through overuse and misuse of these agents, many micro-organisms have developed antimicrobial resistance. Oligonucleotide therapeutics have the potential to become the new class of antibacterials capable of treating a broad range of infections. By acting on novel targets, they circumvent current resistance mechanisms and with judicious use, can suppress the rise of future resistance.DNA-TRAP will build on a platform technology that uses proprietary nucleic acid-based Transcription Factor Decoys (TFDs) that act on novel genomic targets by capturing key regulatory proteins to block essential bacterial genes and defeat infection. Taking forward newly emerging insights and expertise that exists within each of the partners and through the mutual secondment of researchers, the project aims to develop a new class of nanoparticulate antibacterials capable of meeting the clinical challenge of drug-resistant infections such as Clostridium difficile and Pseudomonas aeruginosa.DNA-TRAP will establish a lasting, international partnership for transfer of knowledge between Industry and Academia in the field of nanomedicine. Exchange of knowledge and expertise between the partners is key to establishing the fundamental properties of nanostructured drug delivery systems to treat bacterial infections and through this, provide the basis for building a manufacturing platform to advance the experimental therapeutic into clinical trials.17 researchers in the field of drug development and delivery from 2 commercial (SME) and 2 non-commercial partners across 2 member states, will have the opportunity to share and acquire new complementary and multidisciplinary knowledge, through inter-sectoral and interdisciplinary exchange, allowing for the development of new solutions and the establishment of further joint research projects. Dziedzina nauki medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesmicrobiologybacteriologymedical and health scienceshealth sciencesinfectious diseasesmedical and health sciencesmedical biotechnologynanomedicinemedical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance Program(-y) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Zaproszenie do składania wniosków FP7-PEOPLE-2013-IAPP Zobacz inne projekty w ramach tego zaproszenia System finansowania MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Koordynator UNIVERSITY OF EAST ANGLIA Wkład UE € 801 239,73 Adres EARLHAM ROAD NR4 7TJ Norwich Zjednoczone Królestwo Zobacz na mapie Region East of England East Anglia Norwich and East Norfolk Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Christopher Morris (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko CONSORZIO INTERUNIVERSITARIO PERLO SVILUPPO DEI SISTEMI A GRANDE INTERFASE Włochy Wkład UE € 560 610,14 Adres VIA DELLA LASTRUCCIA 3 50019 Firenze Zobacz na mapie Region Centro (IT) Toscana Firenze Rodzaj działalności Research Organisations Kontakt administracyjny Debora Berti (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych PROCARTA BIOSYSTEMS LIMITED Zakończenie uczestnictwa Zjednoczone Królestwo Wkład UE € 388 220,14 Adres BANKSIDE 300 PEACHMAN WAY NR7 0LB NORWICH Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Kostas Hatzixanthis (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych NANOVECTOR SRL Włochy Wkład UE € 551 331,87 Adres VIA LIVORNO 60 10144 Torino Zobacz na mapie Region Nord-Ovest Piemonte Torino Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Paolo Gasco (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych TECREA LIMITED Zjednoczone Królestwo Wkład UE € 25 520,00 Adres ROYAL COLLEGE STREET 2 NW1 0NH LONDON Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Liam Good (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych KUECEPT LIMITED Zjednoczone Królestwo Wkład UE € 44 109,12 Adres STATION CLOSE 16-17 EN6 1TL POTTERS BAR HERTS Zobacz na mapie Rodzaj działalności Private for-profit entities (excluding Higher or Secondary Education Establishments) Kontakt administracyjny Cristina Freire (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych