Crimean-Congo Haemorrhagic Fever Vaccine

Deliverables

Demonstrators, pilots, prototypes (2)

RVF-VLPs

RVFV-VLPs expressing CCHFV proteins.

RNA

RNA vaccine.

Publications

Peer reviewed articles (8)

Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle

Author(s): Julia Hartlaub, Benjamin Gutjahr, Christine Fast, Ali Mirazimi, Markus Keller, Martin H. Groschup
Published in: Viruses, 13/7, 2021, Page(s) 1250, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071250

Deciphering Antibody Responses to Orthonairoviruses in Ruminants

Author(s): Julia Hartlaub, Markus Keller, Martin H. Groschup
Published in: Microorganisms, 9/7, 2021, Page(s) 1493, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms9071493

Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV

Author(s): Julia Hartlaub, Felicitas von Arnim, Christine Fast, Ali Mirazimi, Markus Keller, Martin H. Groschup
Published in: Viruses, 13/3, 2021, Page(s) 372, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030372

Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV

Author(s): Julia Hartlaub, Felicitas von Arnim, Christine Fast, Maryna Somova, Ali Mirazimi, Martin H. Groschup, Markus Keller
Published in: Microorganisms, 8/12, 2020, Page(s) 1927, ISSN 2076-2607
Publisher: US National Library of Medicine National Institutes of Health
DOI: 10.3390/microorganisms8121927

Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach

Author(s): Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, Iva Christova, Arina Corli Hitzeroth, Natalie Viljoen, Felicity Jane Burt, Ali Mirazimi, Ola Blixt
Published in: PLOS Neglected Tropical Diseases, 12/7, 2018, Page(s) e0006598, ISSN 1935-2735
Publisher: NIAID
DOI: 10.1371/journal.pntd.0006598

Second International Conference on Crimean-Congo Hemorrhagic Fever

Author(s): Jessica R. Spengler, Dennis A. Bente, Mike Bray, Felicity Burt, Roger Hewson, Gülay Korukluoglu, Ali Mirazimi, Friedemann Weber, Anna Papa
Published in: Antiviral Research, 150, 2018, Page(s) 137-147, ISSN 0166-3542
Publisher: Elsevier BV
DOI: 10.1016/j.antiviral.2017.11.019

Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice

Author(s): Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, Helen Karlberg, Eva Wattrang, Sándor Bereczky, Mehrdad Mousavi-Jazi, Christian Risinger, Gunnel Lindegren, Caroline Vernersson, Janusz Paweska, Petrus Jansen van Vuren, Ola Blixt, Alejandro Brun, Friedemann Weber, Ali Mirazimi
Published in: Journal of Virology, 91/10, 2017, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/JVI.02076-16

Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle

Author(s): Julia Hartlaub, Oluwafemi B. Daodu, Balal Sadeghi, Markus Keller, James Olopade, Daniel Oluwayelu, Martin H. Groschup
Published in: Viruses, 13/7, 2021, Page(s) 1398, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071398