Crimean-Congo Haemorrhagic Fever Vaccine

Risultati finali

DIVA

DIVA vaccine.

RVF-VLPs

RVFV-VLPs expressing CCHFV proteins.

RNA

RNA vaccine.

Pubblicazioni

Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle

Autori: Julia Hartlaub, Benjamin Gutjahr, Christine Fast, Ali Mirazimi, Markus Keller, Martin H. Groschup
Pubblicato in: Viruses, Numero 13/7, 2021, Pagina/e 1250, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071250

The interplays between Crimean-Congo hemorrhagic fever virus (CCHFV) M segment-encoded accessory proteins and structural proteins promote virus assembly and infectivity

Autori: Natalia Freitas; Margot Enguehard; Solène Denolly; Camille Levy; Gregory Neveu; Solène Lerolle; Stephanie Devignot; Friedemann Weber; Eric Bergeron; Vincent Legros; François-Loïc Cosset
Pubblicato in: PLOS Pathogens, Numero 16, 2020, ISSN 1553-7366
Editore: Public Library of Science
DOI: 10.1371/journal.ppat.1008850

Systems-level temporal immune-metabolic profile in Crimean-Congo hemorrhagic fever virus infection

Autori: Anoop T. Ambikana, Nazif Elaldib, Sara Svensson- Akusjärvia, Binnur Bagcic, Ayse Nur Pektasd, Roger Hewsone,f, Gokhan Bagcig, Mehmet Araslih, Sofia Appelbergi, Adil Mardinogluj,k, Vikas Sooda,l, Ákos Végvárim, Rui Benfeitasa, Soham Guptaa, Ilhan Cetinn, Ali Mirazimii,o,p, and Ujjwal Neogia,
Pubblicato in: Proceedings of the National Academy of Sciences (PNAS), Numero September 5, 2023, 120 (37), 2023, Pagina/e e2304722120, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2304722120

Nucleoside-Modified mRNA Vaccines Protect IFNAR–/– Mice against Crimean-Congo Hemorrhagic Fever Virus Infection

Autori: Sofia Appelberg; Lijo John; Norbert Pardi; Ákos Végvári; Sándor Bereczky; Gustaf Ahlén; Vanessa Monteil; Samir Abdurahman; Flora Mikaeloff; Mitchell Beattie; Ying Tam ; Matti Sällberg; Ujjwal Neogi; Drew Weissman; Ali Mirazimi
Pubblicato in: Journal of Virology, Numero 96, 2022, Pagina/e e01568-21, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/jvi.01568-21

Deciphering Antibody Responses to Orthonairoviruses in Ruminants

Autori: Julia Hartlaub, Markus Keller, Martin H. Groschup
Pubblicato in: Microorganisms, Numero 9/7, 2021, Pagina/e 1493, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms9071493

Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge

Autori: Sandra Moreno; Eva Calvo-Pinilla; Stephanie Devignot; Friedemann Weber; Javier Ortego; Alejandro Brun
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 14, 2020, ISSN 1935-2727
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0008942

Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model

Autori: David W. Hawman; Kimberly Meade-White; Shanna Leventhal; Sofia Appelberg; Gustaf Ahlén; Negin Nikouyan; Chad Clancy; Brian Smith; Patrick Hanley; Jamie Lovaglio; Ali Mirazimi; Matti Sällberg; Heinz Feldmann
Pubblicato in: Molecular Therapy, Numero 31, 2022, Pagina/e VOLUME 31, ISSUE 2, P387-397, ISSN 1525-0016
Editore: Nature Publishing Group
DOI: 10.1016/j.ymthe.2022.09.016

Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV

Autori: Julia Hartlaub, Felicitas von Arnim, Christine Fast, Ali Mirazimi, Markus Keller, Martin H. Groschup
Pubblicato in: Viruses, Numero 13/3, 2021, Pagina/e 372, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030372

Comparison of Crimean-Congo Hemorrhagic Fever Virus and Aigai Virus in Life Cycle Modeling Systems Reveals a Difference in L Protein Activity

Autori: Matthew J. Pickin; Stéphanie Devignot; Friedemann Weber; Martin H. Groschup
Pubblicato in: Journal of Virology, Numero 96, 2022, Pagina/e e00599-22, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/jvi.00599-22

Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV

Autori: Julia Hartlaub, Felicitas von Arnim, Christine Fast, Maryna Somova, Ali Mirazimi, Martin H. Groschup, Markus Keller
Pubblicato in: Microorganisms, Numero 8/12, 2020, Pagina/e 1927, ISSN 2076-2607
Editore: US National Library of Medicine National Institutes of Health
DOI: 10.3390/microorganisms8121927

Epitope-mapping of the glycoprotein from Crimean-Congo hemorrhagic fever virus using a microarray approach

Autori: Amanda Fritzen, Christian Risinger, Gulay Korukluoglu, Iva Christova, Arina Corli Hitzeroth, Natalie Viljoen, Felicity Jane Burt, Ali Mirazimi, Ola Blixt
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 12/7, 2018, Pagina/e e0006598, ISSN 1935-2735
Editore: NIAID
DOI: 10.1371/journal.pntd.0006598

Second International Conference on Crimean-Congo Hemorrhagic Fever

Autori: Jessica R. Spengler, Dennis A. Bente, Mike Bray, Felicity Burt, Roger Hewson, Gülay Korukluoglu, Ali Mirazimi, Friedemann Weber, Anna Papa
Pubblicato in: Antiviral Research, Numero 150, 2018, Pagina/e 137-147, ISSN 0166-3542
Editore: Elsevier BV
DOI: 10.1016/j.antiviral.2017.11.019

Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice

Autori: Jorma Hinkula, Stéphanie Devignot, Sara Åkerström, Helen Karlberg, Eva Wattrang, Sándor Bereczky, Mehrdad Mousavi-Jazi, Christian Risinger, Gunnel Lindegren, Caroline Vernersson, Janusz Paweska, Petrus Jansen van Vuren, Ola Blixt, Alejandro Brun, Friedemann Weber, Ali Mirazimi
Pubblicato in: Journal of Virology, Numero 91/10, 2017, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/JVI.02076-16

Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle

Autori: Julia Hartlaub, Oluwafemi B. Daodu, Balal Sadeghi, Markus Keller, James Olopade, Daniel Oluwayelu, Martin H. Groschup
Pubblicato in: Viruses, Numero 13/7, 2021, Pagina/e 1398, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071398

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target

Autori: Ujjwal Neogi; Nazif Elaldi; Sofia Appelberg; Anoop Ambikan; Emma Kennedy; Stuart Dowall; Binnur K Bagci; Soham Gupta; Jimmy E Rodriguez; Sara Svensson-Akusjärvi; Vanessa Monteil; Akos Vegvari; Rui Benfeitas; Akhil Banerjea; Friedemann Weber; Roger Hewson; Ali Mirazimi
Pubblicato in: eLife, Numero 11, 2022, Pagina/e e76071, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.76071

ISG15 overexpression compensates the defect of Crimean-Congo hemorrhagic fever virus polymerase bearing a protease-inactive ovarian tumor domain

Autori: Stephanie Devignot; Thilo Kromer; Ali Mirazimi; Friedemann Weber
Pubblicato in: PLOS Neglected Tropical Diseases, Numero 14, 2020, Pagina/e 1-24, ISSN 1935-2727
Editore: Public Library of Science
DOI: 10.1371/journal.pntd.0008610

Risultati finali

Pubblicazioni

Condividi questa pagina

Scarica