AI-augmented, Multiscale Image-based Diagnostics of Chronic Kidney Disease

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Multi-institutional PET/CT image segmentation using federated deep transformer learning

Autori: Shiri I, Razeghi B, Vafaei Sadr A, Amini M, Salimi Y, Ferdowsi S, Boor P, Gündüz D, Voloshynovskiy S, Zaidi H
Pubblicato in: Comput Methods Programs Biomed, 2023, ISSN 0169-2607
Editore: Elsevier BV
DOI: 10.1016/j.cmpb.2023.107706

Extending the landscape of omics technologies by pathomics

Autori: Bülow RD, Hölscher DL, Costa IG, Boor P
Pubblicato in: NPJ Syst Biol Appl., 2023, ISSN 2056-7189
Editore: Springer Nature
DOI: 10.1038/s41540-023-00301-9

Kidney fibrosis: Emerging diagnostic and therapeutic strategies

Autori: Klinkhammer BM, Boor P
Pubblicato in: Mol Aspects Med., 2023, ISSN 0098-2997
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.mam.2023.101206

Renal Denervation Prevents Atrial Arrhythmogenic Substrate Development in CKD

Autori: Hohl M, Selejan SR, Wintrich J, Lehnert U, Speer T, Schneider C, Mauz M, Markwirth P, Wong DWL, Boor P, Kazakov A, Mollenhauer M, Linz B, Klinkhammer BM, Hübner U, Ukena C, Moellmann J, Lehrke M, Wagenpfeil S, Werner C, Linz D, Mahfoud F, Böhm M
Pubblicato in: Circ Res, 2022, ISSN 0009-7330
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.121.320104

Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria

Autori: Gianmoena K, Gasparoni N, Jashari A, Gabrys P, Grgas K, Ghallab A, Nordström K, Gasparoni G, Reinders J, Edlund K, Godoy P, Schriewer A, Hayen H, Hudert CA, Damm G, Seehofer D, Weiss TS, Boor P, Anders H-J, Motrapu M, Jansen P, Schiergens TS, Falk-Paulsen M, Rosenstiel P, Lisowski C, Salido E, Marchan R, Walter J, Hengstler JG, Cadenas C
Pubblicato in: Cell Rep, 2021, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2021.109526

Current kidney function parameters overestimate kidney tissue repair in reversible experimental kidney disease

Autori: Klinkhammer BM, Buchtler S, Djudjaj S, Bouteldja N, Palsson R, Edvardsson VO, Thorsteinsdottir M, Floege J, Mack M, Boor P
Pubblicato in: Kidney Int., 2022, ISSN 0085-2538
Editore: Blackwell Publishing Inc.
DOI: 10.18154/rwth-conv-249847

CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes

Autori: Olschok K, Han L, de Toledo MAS, Böhnke J, Graßhoff M, Costa IG, Theocharides A, Maurer A, Schüler HM, Buhl EM, Pannen K, Baumeister J, Kalmer M, Gupta S, Boor P, Gezer D, Brümmendorf TH, Zenke M, Chatain N, Koschmieder S
Pubblicato in: Stem Cell Reports, 2021, ISSN 2213-6711
Editore: Cell Press
DOI: 10.1016/j.stemcr.2021.09.019

Predicting Future Outcomes from Kidney Biopsies with MCD/FSGS Lesions: Opportunities and Limitations

Autori: Anders HJ, Boor P
Pubblicato in: J Am Soc Nephrol., 2022, ISSN 1555-9041
Editore: American Society of Nephrology
DOI: 10.1681/asn.2022040506

Stain-Independent Deep Learning-Based Analysis of Digital Kidney Histopathology

Autori: Bouteldja N, Hölscher DL, Klinkhammer BM, Buelow RD, Lotz J, Weiss N, Daniel C, Amann K, Boor P
Pubblicato in: Am J Pathol., 2023, ISSN 0002-9440
Editore: American Society for Investigative Pathology
DOI: 10.1016/j.ajpath.2022.09.011

Deep Learning-based classification of kidney transplant pathology: a retrospective, multicente, proof-of-concept study

Autori: "Kers J#, Bülow RD#, Klinkhammer BM, Breimer GE, Fontana F, Abiola AA, Hofstraat R, Corthals GL, Sengers HP, Djudjaj S, von Stillfried S, Hölscher DL, Pieters TT, van Zuilen AD, Bemelman FJ, Nurmohamed AS, Naesens M, Roelofs JJTH, Florquin S, Floege J, Nguyen TQ, Kather JN, Boor P"
Pubblicato in: Lancet Digit Health., 2022, ISSN 2589-7500
Editore: Oxford: Elsevier Ltd.
DOI: 10.1016/s2589-7500(21)00211-9

Deep Learning for the detection of microsatellite instability from histology images in colorectal cancer: a systematic literature review

Autori: Echle A, Laleh NG, Schrammen PL, West NP, Trautwein C, Brinker TJ, Gruber SB, Buelow RD, Boor P, Grabsch HI, Quirke P, Kather JN
Pubblicato in: J Immuno, 2021, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.3390/cancers13030391

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

Autori: Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, Deutsche COVID-19 OMIC
Pubblicato in: Cell, 2021, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2021.11.033

Inhibition of the Renal Apical Sodium Dependent Bile Acid Transporter Prevents Cholemic Nephropathy in Mice with Obstructive Cholestasis

Autori: Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Ma
Pubblicato in: J Hepatol, 2023, ISSN 0168-8278
Editore: Elsevier BV
DOI: 10.1016/j.jhep.2023.10.035

Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology

Autori: Ghaffari Laleh N, Muti HS, Loeffler CML, Echle A, Saldanha OL, Mahmood F, Lu MY, Trautwein C, Langer R, Dislich B, Buelow RD, Grabsch HI, Brenner H, Chang-Claude J, Alwers E, Brinker TJ, Khader F, Truhn D, Gaisa NT, Boor P, Hoffmeister M, Schulz V, Kather JN
Pubblicato in: Med Image Anal., 2022, ISSN 1361-8415
Editore: Elsevier BV
DOI: 10.1016/j.media.2022.102474

Operational greenhouse-gas emissions of deep learning in digital pathology: a modelling study

Autori: Vafaei Sadr A, Bülow R, von Stillfried S, Schmitz NEJ, Pilva P, Hölscher DL, Ha PP, Schweiker M, Boor P
Pubblicato in: Lancet Digit Health, 2023, ISSN 2589-7500
Editore: Oxford: Elsevier Ltd.
DOI: 10.1016/s2589-7500(23)00219-4

The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis

Autori: Ting Jia, Tong Xu, Bart Smeets, Eva Miriam Buhl, Marcus Johannes Moeller, Jürgen Floege, Barbara Mara Klinkhammer, Peter Boor
Pubblicato in: J Am Soc Nephrol, 2023, ISSN 1046-6673
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2022040491

Inflammation and vascular remodeling in COVID-19 hearts

Autori: Werlein C, Ackermann M, Stark H, Shah HR, Tzankov A, Haslbauer JD, von Stillfried S, Bülow RD, El-Armouche A, Kuenzel S, Robertus JL, Reichardt M, Haverich A, Höfer A, Neubert L, Plucinski E, Braubach P, Verleden S, Salditt T, Marx N, Welte T, Bauersachs J, Kreipe HH, Mentzer SJ, Boor P, Black SM, Länger F, Kuehnel M, Jonigk D
Pubblicato in: Angiogenesis, 2022, ISSN 0969-6970
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10456-022-09860-7

Mapping cardiac remodeling in chronic kidney disease

Autori: Kaesler N, Cheng M, Nagai J, O'Sullivan J, Peisker F, Bindels EMJ, Babler A, Moellmann J, Droste P, Franciosa G, Dugourd A, Saez-Rodriguez J, Neuss S, Lehrke M, Boor P, Goettsch C, Olsen JV, Speer T, Lu TS, Lim K, Floege J, Denby L, Costa I, Kramann R
Pubblicato in: Sci Adv, 2023, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.adj4846

Tackling stain variability using CycleGAN-based stain augmentation

Autori: Bouteldja N, Hölscher DL, Bülow RD, Roberts ISD, Coppo R, Boor P
Pubblicato in: J Pathol Inform., 2022, ISSN 2229-5089
Editore: Medknow publication
DOI: 10.1016/j.jpi.2022.100140

The potential of artificial intelligence-based applications in kidney pathology

Autori: Bülow RD, Marsh JN, Swamidass J, Gaut JP, Boor P
Pubblicato in: Curr Opin Nephrol Hypertens, 2022, ISSN 1062-4821
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/mnh.0000000000000784

A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology.

Autori: Petersen J, Englmaier L, Artemov AV, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov EE, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti ME, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji RS, Grabowski A, Buhl ME, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Ko
Pubblicato in: Nat Commun, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-38663-7

Subcellular spatio-temporal intravital kinetics of aflatoxin B 1 and ochratoxin A in liver and kidney

Autori: Ghallab A, Hassan R, Myllys M, Albrecht W, Friebel A, Hoehme S, Hofmann U, Seddek A-L, Braeuning A, Kuepfer L, Cramer B, Humpf H-U, Boor P, Degen GH, Hengstler JG
Pubblicato in: Arch Toxicol, 2021, ISSN 0340-5761
Editore: Springer Verlag
DOI: 10.1007/s00204-021-03073-5

Banff Digital Pathology Working Group: Image Bank, Artificial Intelligence Algorithm, and Challenge Trial Developments

Autori: Farris AB, Alexander MP, Balis UGJ, Barisoni L, Boor P, Bülow RD, Cornell LD, Demetris AJ, Farkash E, Hermsen M, Hogan J, Kain R, Kers J, Kong J, Levenson RM, Loupy A, Naesens M, Sarder P, Tomaszewski JE, van der Laak J, van Midden D, Yagi Y, Solez K
Pubblicato in: Transpl Int., 2023, ISSN 0934-0874
Editore: Blackwell Publishing Inc.
DOI: 10.18154/rwth-conv-247345

Interleukin-1α (IL-1α) is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease

Autori: Schunk S, Triem S, Schmit D, Zewinger S, Sarakpi T, Becker E, Hütter G, Wrublewsky S, Küting F, Hohl M, Alansary D, Roma LP, Lipp P, Möllmann J, Lehrke M, Laschke MW, Menger MD, Kramann R, Boor P, Jahnen-Dechent W, März W, Böhm M, Laufs U, Niemeyer BA, Fliser D, Ampofo E, Speer T
Pubblicato in: Circulation, 2021, ISSN 0009-7322
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circulationaha.121.053547

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